Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine.
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Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain AntibodiesDisruption of the Putative Vascular Leak Peptide Sequence in the Stabilized Ricin Vaccine Candidate RTA1-33/44-198Stability of isolated antibody-antigen complexes as a predictive tool for selecting toxin neutralizing antibodiesNovel Ricin Subunit Antigens With Enhanced Capacity to Elicit Toxin-Neutralizing Antibody Responses in Mice.Differential neutralizing activities of a single domain camelid antibody (VHH) specific for ricin toxin's binding subunit (RTB).Localization of non-linear neutralizing B cell epitopes on ricin toxin's enzymatic subunit (RTA)Combination of two candidate subunit vaccine antigens elicits protective immunity to ricin and anthrax toxin in miceThermostable ricin vaccine protects rhesus macaques against aerosolized ricin: Epitope-specific neutralizing antibodies correlate with protection.Strong protection against ricin challenge induced by a novel modified ricin A-chain protein in mouse model.A novel recombinant vaccine protecting mice against abrin intoxication.Comparative Adjuvant Effects of Type II Heat-Labile Enterotoxins in Combination with Two Different Candidate Ricin Toxin Vaccine Antigens.Neutralizing Monoclonal Antibodies against Disparate Epitopes on Ricin Toxin's Enzymatic Subunit Interfere with Intracellular Toxin Transport.Comparative efficacy of two leading candidate ricin toxin a subunit vaccines in mice.LT-IIb(T13I), a non-toxic type II heat-labile enterotoxin, augments the capacity of a ricin toxin subunit vaccine to evoke neutralizing antibodies and protective immunityNeutralizing monoclonal antibodies against ricin's enzymatic subunit interfere with protein disulfide isomerase-mediated reduction of ricin holotoxin in vitro.Recent advances in the development of vaccines against ricin.Toxicity of ricin A chain is reduced in mammalian cells by inhibiting its interaction with the ribosome.Progress and challenges associated with the development of ricin toxin subunit vaccines.Enhancement of humoral immunity by the type II heat-labile enterotoxin LT-IIb is dependent upon IL-6 and neutrophils.Effect of single-point mutations on the stability and immunogenicity of a recombinant ricin A chain subunit vaccine antigenPlant Ribosome-Inactivating Proteins: Progesses, Challenges and Biotechnological Applications (and a Few Digressions).High-Resolution Epitope Positioning of a Large Collection of Neutralizing and Nonneutralizing Single-Domain Antibodies on the Enzymatic and Binding Subunits of Ricin Toxin.Ricin poisoning: a case of internet-assisted parasuicide.High-Definition Mapping of Four Spatially Distinct Neutralizing Epitope Clusters on RiVax, a Candidate Ricin Toxin Subunit Vaccine.Biochemical and aerosol characterization of ricin for use in non-clinical efficacy studies.Alpha-galactosylceramide (αGalCer) Enhances Vaccine-induced Protection in a Model of Ricin Intoxication.
P2860
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P2860
Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
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2012年學術文章
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2012年學術文章
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name
Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine.
@ast
Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine.
@en
type
label
Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine.
@ast
Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine.
@en
prefLabel
Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine.
@ast
Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine.
@en
P2093
P2860
P356
P1476
Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine.
@en
P2093
Ellen S Vitetta
Joan E Smallshaw
John Schindler
P2860
P304
P356
10.1128/CVI.00381-12
P577
2012-08-22T00:00:00Z