Impaired cytotoxic T lymphocyte recognition due to genetic variations in the main immunogenic region of the human immunodeficiency virus 1 NEF protein
about
Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infectionPositive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infectionMultiepitopic B- and T-cell responses induced in humans by a human immunodeficiency virus type 1 lipopeptide vaccineNaturally occurring TAP-dependent specific T-cell tolerance for a variant of an immunodominant retroviral cytotoxic T-lymphocyte epitope.Antigenic drift in the influenza A virus (H3N2) nucleoprotein and escape from recognition by cytotoxic T lymphocytes.Efficient processing of the immunodominant, HLA-A*0201-restricted human immunodeficiency virus type 1 cytotoxic T-lymphocyte epitope despite multiple variations in the epitope flanking sequencesImpairment of Gag-specific CD8(+) T-cell function in mucosal and systemic compartments of simian immunodeficiency virus mac251- and simian-human immunodeficiency virus KU2-infected macaques.Analysis of infectious virus clones from two HIV-1 superinfection cases suggests that the primary strains have lower fitness.Dendritic cells restore CD8+ T cell reactivity to autologous HIV-1Selection of virus variants and emergence of virus escape mutants after immunization with an epitope vaccine.Memory CD8+ T cells from naturally acquired primary dengue virus infection are highly cross-reactive.Cellular HIV-1 immune responses in natural infection and after genetic immunization.The differential ability of HLA B*5701+ long-term nonprogressors and progressors to restrict human immunodeficiency virus replication is not caused by loss of recognition of autologous viral gag sequences.Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infectionMagnitude of functional CD8+ T-cell responses to the gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma.Comprehensive screening for human immunodeficiency virus type 1 subtype-specific CD8 cytotoxic T lymphocytes and definition of degenerate epitopes restricted by HLA-A0207 and -C(W)0304 allelesThe efficacy of T cell-mediated immune responses is reduced by the envelope protein of the chimeric HIV-1/SIV-KB9 virus in vivo.The functional CD8 T cell response to HIV becomes type-specific in progressive disease.Immunobiology of cytotoxic T-cell escape mutants of lymphocytic choriomeningitis virusHigh levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors.Emergence of virus escape mutants after immunization with epitope vaccine.CD8+ T-cell epitopes within the surface glycoprotein of a neurotropic coronavirus and correlation with pathogenicity.Unusually high frequency of Epstein-Barr virus genetic variants in Papua New Guinea that can escape cytotoxic T-cell recognition: implications for virus evolution.Specificity of the H-2 L(d)-restricted cytotoxic T-lymphocyte response to the mouse hepatitis virus nucleocapsid proteinGenomic quasispecies associated with the initiation of infection and disease in ponies experimentally infected with equine infectious anemia virus.Overlapping epitopes in human immunodeficiency virus type 1 gp120 presented by HLA A, B, and C molecules: effects of viral variation on cytotoxic T-lymphocyte recognitionEvolution of mouse hepatitis virus: detection and characterization of spike deletion variants during persistent infectionRapid HIV-1 Disease Progression in Individuals Infected with a Virus Adapted to Its Host Population.Immune selection in vitro reveals human immunodeficiency virus type 1 Nef sequence motifs important for its immune evasion function in vivo.Maintenance of viral suppression in HIV-1-infected HLA-B*57+ elite suppressors despite CTL escape mutationsVirus escape from CTL recognitionCytotoxic T lymphocyte epitopes of HIV-1 Nef: Generation of multiple definitive major histocompatibility complex class I ligands by proteasomes.The human immunodeficiency virus type 1 (HIV-1) Vpu protein interferes with an early step in the biosynthesis of major histocompatibility complex (MHC) class I molecules.Patterns of immunodominance in HIV-1-specific cytotoxic T lymphocyte responses in two human histocompatibility leukocyte antigens (HLA)-identical siblings with HLA-A*0201 are influenced by epitope mutation.Long-term specific immune responses induced in humans by a human immunodeficiency virus type 1 lipopeptide vaccine: characterization of CD8+-T-cell epitopes recognized.Frequency of HLA allele-specific peptide motifs in HIV-1 proteins correlates with the allele's association with relative rates of disease progression after HIV-1 infection.Targeting of conserved gag-epitopes in early HIV infection is associated with lower plasma viral load and slower CD4(+) T cell depletion.Frequent transmission of cytotoxic-T-lymphocyte escape mutants of human immunodeficiency virus type 1 in the highly HLA-A24-positive Japanese populationSimian-human immunodeficiency virus escape from cytotoxic T-lymphocyte recognition at a structurally constrained epitope.Predicting the impact of blocking human immunodeficiency virus type 1 Nef in vivo.
P2860
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P2860
Impaired cytotoxic T lymphocyte recognition due to genetic variations in the main immunogenic region of the human immunodeficiency virus 1 NEF protein
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
Impaired cytotoxic T lymphocyt ...... deficiency virus 1 NEF protein
@ast
Impaired cytotoxic T lymphocyt ...... deficiency virus 1 NEF protein
@en
type
label
Impaired cytotoxic T lymphocyt ...... deficiency virus 1 NEF protein
@ast
Impaired cytotoxic T lymphocyt ...... deficiency virus 1 NEF protein
@en
prefLabel
Impaired cytotoxic T lymphocyt ...... deficiency virus 1 NEF protein
@ast
Impaired cytotoxic T lymphocyt ...... deficiency virus 1 NEF protein
@en
P2093
P2860
P356
P1476
Impaired cytotoxic T lymphocyt ...... deficiency virus 1 NEF protein
@en
P2093
Couillin I
Culmann-Penciolelli B
Guillet JG
Saragosti S
P2860
P304
P356
10.1084/JEM.180.3.1129
P407
P577
1994-09-01T00:00:00Z