An unstable beta 2-microglobulin: major histocompatibility complex class I heavy chain intermediate dissociates from calnexin and then is stabilized by binding peptide.
about
The molecular chaperone calnexin binds Glc1Man9GlcNAc2 oligosaccharide as an initial step in recognizing unfolded glycoproteinsCalreticulin recognizes misfolded HLA-A2 heavy chainsPathways for lipid antigen presentation by CD1 molecules: nowhere for intracellular pathogens to hide.Getting the inside out: the transporter associated with antigen processing (TAP) and the presentation of viral antigenTargeted delivery of an antigenic peptide to the endoplasmic reticulum: application for development of a peptide therapy for ankylosing spondylitis.The molecular chaperone calnexin facilitates folding and assembly of class I histocompatibility molecules.Tapasin and other chaperones: models of the MHC class I loading complex.LMP-associated proteolytic activities and TAP-dependent peptide transport for class 1 MHC molecules are suppressed in cell lines transformed by the highly oncogenic adenovirus 12.MHC class I molecules form ternary complexes with calnexin and TAP and undergo peptide-regulated interaction with TAP via their extracellular domains.Loss of functional beta 2-microglobulin in metastatic melanomas from five patients receiving immunotherapyTotal HLA class I loss in a sarcomatoid renal carcinoma cell line caused by the coexistence of distinct mutations in the two encoding beta2-microglobulin genes.Calnexin and calreticulin bind to enzymically active tissue-type plasminogen activator during biosynthesis and are not required for folding to the native conformationCalnexin, calreticulin, and ERp57 cooperate in disulfide bond formation in human CD1d heavy chain.Blocked transport of soluble K(b) molecules containing connecting peptide segment involved in calnexin association.Placental expression of HLA class I genes.Association of the invariant chain with major histocompatibility complex class I molecules directs trafficking to endocytic compartments.Targeted Delivery of the HLA-B∗27-Binding Peptide into the Endoplasmic Reticulum Suppresses the IL-23/IL-17 Axis of Immune Cells in Spondylarthritis.
P2860
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P2860
An unstable beta 2-microglobulin: major histocompatibility complex class I heavy chain intermediate dissociates from calnexin and then is stabilized by binding peptide.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
An unstable beta 2-microglobul ...... stabilized by binding peptide.
@ast
An unstable beta 2-microglobul ...... stabilized by binding peptide.
@en
type
label
An unstable beta 2-microglobul ...... stabilized by binding peptide.
@ast
An unstable beta 2-microglobul ...... stabilized by binding peptide.
@en
prefLabel
An unstable beta 2-microglobul ...... stabilized by binding peptide.
@ast
An unstable beta 2-microglobul ...... stabilized by binding peptide.
@en
P2860
P356
P1476
An unstable beta 2-microglobul ...... stabilized by binding peptide.
@en
P2093
P2860
P304
P356
10.1084/JEM.180.6.2163
P407
P577
1994-12-01T00:00:00Z