Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP.
about
4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaBCD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligandTherapeutic targets for HIV-1 infection in the host proteome.4-1BB (CD137) controls the clonal expansion and survival of CD8 T cells in vivo but does not contribute to the development of cytotoxicityTWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosisGrb2 forms an inducible protein complex with CD28 through a Src homology 3 domain-proline interactionAnalysis of 4-1BBL and laminin binding to murine 4-1BB, a member of the tumor necrosis factor receptor superfamily, and comparison with human 4-1BBMolecular cloning of agonistic and antagonistic monoclonal antibodies against human 4-1BB.Recombinant antigen-enterotoxin A2/B chimeric mucosal immunogens differentially enhance antibody responses and B7-dependent costimulation of CD4(+) T cells.CD137-mediated immunotherapy for allergic asthmaCostimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor.CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 miceTherapeutic vaccination with tumor cells that engage CD137.Hu.4-1BB-Fc fusion protein inhibits allergic inflammation and airway hyperresponsiveness in a murine model of asthmaInterleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice.Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy.CD28-independent induction of T helper cells and immunoglobulin class switches requires costimulation by the heat-stable antigen.Expression of co-stimulator 4-1BB molecule in hepatocellular carcinoma and adjacent non-tumor liver tissue, and its possible role in tumor immunityConnecting the Dots: Therapy-Induced Senescence and a Tumor-Suppressive Immune Microenvironment.Regulation of mouse 4-1BB expression: multiple promoter usages and a splice variant.Deciphering CD137 (4-1BB) signaling in T-cell costimulation for translation into successful cancer immunotherapy.Elevated cyclic AMP levels in T lymphocytes transformed by human T-cell lymphotropic virus type 1.NF-kappaB and AP-1 regulate activation-dependent CD137 (4-1BB) expression in T cells.Recent advances in graft-versus-host disease (GVHD) prevention.CD27 cooperates with the pre-T cell receptor in the regulation of murine T cell development.Immunity in the absence of CD28 and CD137 (4-1BB) molecules.In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses.Enhanced antitumor activity mediated by human 4-1BB-engineered T cells.Tumour rejection by gene transfer of 4-1BB ligand into a CD80(+) murine squamous cell carcinoma and the requirements of co-stimulatory molecules on tumour and host cells.Expression and function of 4-1BB during CD4 versus CD8 T cell responses in vivo.CD137+CD154- Expression As a Regulatory T Cell (Treg)-Specific Activation Signature for Identification and Sorting of Stable Human Tregs from In Vitro Expansion Cultures.Trogocytic CD137 transfer causes an internalization of CD137 ligand on murine APCs leading to reduced T cell costimulation.Serum levels of sCD137 (4-1BB) ligand are prognostic factors for progression in acute myeloid leukemia but not in non-Hodgkin's lymphoma.On the Road to Immunotherapy-Prospects for Treating Head and Neck Cancers With Checkpoint Inhibitor AntibodiesLevels of soluble CD137 are enhanced in sera of leukemia and lymphoma patients and are strongly associated with chronic lymphocytic leukemia
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P2860
Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Role of 4-1BB ligand in costim ...... on on M12 B lymphomas by cAMP.
@ast
Role of 4-1BB ligand in costim ...... on on M12 B lymphomas by cAMP.
@en
type
label
Role of 4-1BB ligand in costim ...... on on M12 B lymphomas by cAMP.
@ast
Role of 4-1BB ligand in costim ...... on on M12 B lymphomas by cAMP.
@en
prefLabel
Role of 4-1BB ligand in costim ...... on on M12 B lymphomas by cAMP.
@ast
Role of 4-1BB ligand in costim ...... on on M12 B lymphomas by cAMP.
@en
P2093
P2860
P356
P1476
Role of 4-1BB ligand in costim ...... on on M12 B lymphomas by cAMP.
@en
P2093
K E Pollok
M A DeBenedette
P2860
P304
P356
10.1084/JEM.181.3.985
P407
P577
1995-03-01T00:00:00Z