Mutational analysis and an alternatively spliced product of B7 defines its CD28/CTLA4-binding site on immunoglobulin C-like domain.

Mutational analysis and an alternatively spliced product of B7 defines its CD28/CTLA4-binding site on immunoglobulin C-like domain.

Item
http://www.wikidata.org/entity/Q36364745
The B7 family of immune-regulatory ligandsIdentification of residues in the V domain of CD80 (B7-1) implicated in functional interactions with CD28 and CTLA4Costimulation of T cellsIdentification of a costimulatory molecule rapidly induced by CD40L as CD44H.Cytotoxic T lymphocytes to an unmutated tumor rejection antigen P1A: normal development but restrained effector function in vivo.B7DC/PDL2 promotes tumor immunity by a PD-1-independent mechanism.CTLA-4-B7 interaction is sufficient to costimulate T cell clonal expansion.B7-CTLA4 interaction enhances both production of antitumor cytotoxic T lymphocytes and resistance to tumor challenge.Non-glycosylated human B7-1(CD80) retains the capacity to bind its counter-receptors.Induction of immunologic tolerance for transplantation.The amino-terminal immunoglobulin-like domain of activated leukocyte cell adhesion molecule binds specifically to the membrane-proximal scavenger receptor cysteine-rich domain of CD6 with a 1:1 stoichiometry.B7.1 expression by the weakly immunogenic F98 rat glioma does not enhance immunogenicity.DNA vaccination with an insulin construct and a chimeric protein binding to both CTLA4 and CD40 ameliorates type 1 diabetes in NOD mice.
P2860

Mutational analysis and an alternatively spliced product of B7 defines its CD28/CTLA4-binding site on immunoglobulin C-like domain.

Item
http://www.wikidata.org/entity/Q36364745
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Mutational analysis and an alt ...... immunoglobulin C-like domain.
@ast
Mutational analysis and an alt ...... immunoglobulin C-like domain.
@en
type
label
Mutational analysis and an alt ...... immunoglobulin C-like domain.
@ast
Mutational analysis and an alt ...... immunoglobulin C-like domain.
@en
prefLabel
Mutational analysis and an alt ...... immunoglobulin C-like domain.
@ast
Mutational analysis and an alt ...... immunoglobulin C-like domain.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Mutational analysis and an alt ...... n immunoglobulin C-like domain
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932