Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells - Wikidata - awgldk - TriplyDB

Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

http://www.wikidata.org/entity/Q36365491

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Annexin-1 modulates T-cell activation and differentiation RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation Enhanced immunogenicity of a functional enzyme by T cell epitope modification Cell fate decision: T-helper 1 and 2 subsets in immune responses.TCR Signal Strength Alters T-DC Activation and Interaction Times and Directs the Outcome of Differentiation Narrowing the Gap: Preserving Repertoire Diversity Despite Clonal Selection during the CD4 T Cell Response Insights into the initiation of type 2 immune responses Dendritic cell subsets in type 1 diabetes: friend or foe?Effective T helper cell responses against retroviruses: are all clonotypes equal?Computational and Empirical Studies Predict Mycobacterium tuberculosis-Specific T Cells as a Biomarker for Infection Outcome.Different Levels of T-Cell Receptor Triggering Induce Distinct Functions in Hepatitis B and Hepatitis C Virus-Specific Human CD4+ T-Cell Clones CD4 T cell cytokine differentiation: the B cell activation molecule, OX40 ligand, instructs CD4 T cells to express interleukin 4 and upregulates expression of the chemokine receptor, Blr-1 DC priming by M. vaccae inhibits Th2 responses in contrast to specific TLR2 priming and is associated with selective activation of the CREB pathway Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells Protease recognition sites in Bet v 1a are cryptic, explaining its slow processing relevant to its allergenicity.Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor.CD4+ T cell subset differentiation and avidity setpoint are dictated by the interplay of cytokine and antigen mediated signals WASp-dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts.Type I (insulin-dependent) diabetes is a Th1- and Th2-mediated autoimmune disease The role of STAT3 and AhR in the differentiation of CD4+ T cells into Th17 and Treg cells.Leishmania major infection of inbred mice: unmasking genetic determinants of infectious diseases.Elongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile.An alternate mechanism of glucocorticoid anti-proliferative effect: promotion of a Th2 cytokine-secreting profile.Murine dendritic cells pulsed in vitro with Toxoplasma gondii antigens induce protective immunity in vivo Priming with secreted glycoprotein G of respiratory syncytial virus (RSV) augments interleukin-5 production and tissue eosinophilia after RSV challenge Induction and regulation of the IgE response.Role of OX40 signals in coordinating CD4 T cell selection, migration, and cytokine differentiation in T helper (Th)1 and Th2 cells Key factors in the development of asthma: atopy.Structural integrity of the antigen is a determinant for the induction of T-helper type-1 immunity in mice by gene gun vaccines against E. coli beta-galactosidase.Leishmaniasis: current status of vaccine development T-cell-receptor-dependent signal intensity dominantly controls CD4(+) T cell polarization In Vivo.Immunity to Chlamydia trachomatis mouse pneumonitis induced by vaccination with live organisms correlates with early granulocyte-macrophage colony-stimulating factor and interleukin-12 production and with dendritic cell-like maturation.Filarial antigens impair the function of human dendritic cells during differentiation TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo.Developmental maturation of innate immune cell function correlates with susceptibility to central nervous system autoimmunity.Regulation of T cell priming by lymphoid stroma.Review article: molecular signals and genetic reprogramming in peripheral T-cell differentiation.Distinct CD4+-T-cell responses to live and heat-inactivated Aspergillus fumigatus conidia.

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P2860

Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

http://www.wikidata.org/entity/Q36365491

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Extent of T cell receptor liga ...... ntiation of naive CD4+ T cells

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P2860

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection.

The importance of Th2 cytokines in protective immunity to nematodes.

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice.

Response of naive antigen-specific CD4+ T cells in vitro: characteristics and antigen-presenting cell requirements

Immune response to chemically modified flagellin. I. Induction of antibody tolerance to flagellin by acetoacetylated derivatives of the protein.

Distinct functional phenotypes of cloned Ia-restricted helper T cells.

Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells.

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.

MHC control of CD4+ T cell subset activation.

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