Positive selection is not required for thymic maturation of transgenic gamma delta T cells.
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γδ T cell surveillance via CD1 moleculesThymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gammaThymic maturation determines gammadelta T cell function, but not their antigen specificitiesT-lineage cells require the thymus but not VDJ recombination to produce IL-17A and regulate granulopoiesis in vivo.Roles of the Src tyrosine kinases Lck and Fyn in regulating gammadeltaTCR signal strengthCutting edge: Intrinsic programming of thymic γδT cells for specific peripheral tissue localization.Some hints concerning the shape of T-cell receptor structures.Stage-dependent reactivity of thymocytes to self-peptide--MHC complexes.Bad can act as a key regulator of T cell apoptosis and T cell development.Premature expression of T cell receptor (TCR)alphabeta suppresses TCRgammadelta gene rearrangement but permits development of gammadelta lineage T cells.Ontogeny of the immune system: gamma/delta and alpha/beta T cells migrate from thymus to the periphery in alternating wavesSignaling efficiency of the T cell receptor controlled by a single amino acid in the beta chain constant region.Recent insights into the signals that control alphabeta/gammadelta-lineage fate.An opposite pattern of selection of a single T cell antigen receptor in the thymus and among intraepithelial lymphocytes.T cell receptor-instructed alphabeta versus gammadelta lineage commitment revealed by single-cell analysis.Development and selection of gammadelta T cells.Intraepithelial lymphocytes: their shared and divergent immunological behaviors in the small and large intestine.Autospecific gammadelta thymocytes that escape negative selection find sanctuary in the intestineInversion of the Vδ1 to Vδ2 γδ T cell ratio in CVID is not restored by IVIg and is associated with immune activation and exhaustion.Ligand recognition during thymic development and gammadelta T cell function specification.Disorderly conduct in gammadelta versus alphabeta T cell lineage commitment.Towards a molecular understanding of the differential signals regulating alphabeta/gammadelta T lineage choice.γδ T cell receptor ligands and modes of antigen recognitionDevelopment and function of interleukin 17-producing γδ T cells.Interleukin 15 controls the generation of the restricted T cell receptor repertoire of gamma delta intestinal intraepithelial lymphocytes.Lifespan of gamma/delta T cells.T-cell fate.Role of a selecting ligand in shaping the murine γδ-TCR repertoire.
P2860
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P2860
Positive selection is not required for thymic maturation of transgenic gamma delta T cells.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Positive selection is not requ ...... ransgenic gamma delta T cells.
@ast
Positive selection is not requ ...... ransgenic gamma delta T cells.
@en
type
label
Positive selection is not requ ...... ransgenic gamma delta T cells.
@ast
Positive selection is not requ ...... ransgenic gamma delta T cells.
@en
prefLabel
Positive selection is not requ ...... ransgenic gamma delta T cells.
@ast
Positive selection is not requ ...... ransgenic gamma delta T cells.
@en
P2860
P356
P1476
Positive selection is not requ ...... ransgenic gamma delta T cells.
@en
P2093
Fowlkes BJ
Schweighoffer E
P2860
P304
P356
10.1084/JEM.183.5.2033
P407
P577
1996-05-01T00:00:00Z