Taxol induces the assembly of free microtubules in living cells and blocks the organizing capacity of the centrosomes and kinetochores. - Wikidata - awgldk - TriplyDB

Taxol induces the assembly of free microtubules in living cells and blocks the organizing capacity of the centrosomes and kinetochores.

Taxol induces the assembly of free microtubules in living cells and blocks the organizing capacity of the centrosomes and kinetochores.

http://www.wikidata.org/entity/Q36368107

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GSK-3beta-regulated interaction of BICD with dynein is involved in microtubule anchorage at centrosome Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells Novel features of the light chain of microtubule-associated protein MAP1B: microtubule stabilization, self interaction, actin filament binding, and regulation by the heavy chain Cytoskeletal control of gene expression: depolymerization of microtubules activates NF-kappa B Widespread cellular distribution of MAP-1A (microtubule-associated protein 1A) in the mitotic spindle and on interphase microtubules Polyglutamylated Tubulin Binding Protein C1orf96/CSAP Is Involved in Microtubule Stabilization in Mitotic Spindles Taxol crystals can masquerade as stabilized microtubules Microtubule bundling by tau proteins in vivo: analysis of functional domains Taxol-stabilized microtubules can position the cytokinetic furrow in mammalian cells.Imaging hematopoietic precursor division in real time.Live-cell analysis of mitotic spindle formation in taxol-treated cells.Host cell and malarial targets for docetaxel (Taxotere) during the erythrocytic development of Plasmodium falciparum.Fluorescent taxoids as probes of the microtubule cytoskeleton.MAPK-activated protein kinase 2 is required for mouse meiotic spindle assembly and kinetochore-microtubule attachment.The multiple facets of drug resistance: one history, different approaches.Hecate/Grip2a acts to reorganize the cytoskeleton in the symmetry-breaking event of embryonic axis induction.Contraction due to microtubule disruption is associated with increased phosphorylation of myosin regulatory light chain Identification of centrosomal proteins in a human lymphoblastic cell line How Taxol/paclitaxel kills cancer cells.Mechanisms of Myofascial Pain Increased spinal cord Na⁺-K⁺-2Cl⁻ cotransporter-1 (NKCC1) activity contributes to impairment of synaptic inhibition in paclitaxel-induced neuropathic pain Disruption of microtubule organization and centrosome function by expression of tobacco mosaic virus movement protein Nonuniform microtubular polarity established by CHO1/MKLP1 motor protein is necessary for process formation of podocytes.Drugs that target dynamic microtubules: a new molecular perspective Pluronic F127 polymeric micelles for co-delivery of paclitaxel and lapatinib against metastatic breast cancer: preparation, optimization and in vitro evaluation.Invasion of cultured human epithelial cells by Klebsiella pneumoniae isolated from the urinary tract.Protective effect of a microtubule stabilizer taxol on caerulein-induced acute pancreatitis in rat.Macromolecular crowding regulates assembly of mRNA stress granules after osmotic stress: new role for compatible osmolytes Role of the microtubular system in morphological organization of normal and oncogene-transfected epithelial cells.Combined-modality radioimmunotherapy: synergistic effect of paclitaxel and additive effect of bevacizumab Morphometry of platelet internal contraction.Influence of a microtubule stabilizing agent on platelet structural physiology.S-phase specificity of cell killing by docetaxel (Taxotere) in synchronised HeLa cells.Taxol binds to cellular microtubules Action of taxol on mitosis: modification of microtubule arrangements and function of the mitotic spindle in Haemanthus endosperm Microtubule-organizing centers abnormal in number, structure, and nucleating activity in x-irradiated mammalian cells Cytoplasmic microtubule assembly-disassembly from endogenous tubulin in a Brij-lysed cell model.Taxol inhibits the nuclear movements during fertilization and induces asters in unfertilized sea urchin eggs Inhibition of neurite initiation and growth by taxol Analysis of the role of microfilaments and microtubules in acquisition of bipolarity and elongation of fibroblasts in hydrated collagen gels

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P2860

Taxol induces the assembly of free microtubules in living cells and blocks the organizing capacity of the centrosomes and kinetochores.

http://www.wikidata.org/entity/Q36368107

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1981 nî lūn-bûn

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1981年學術文章

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Proceedings of the National Academy of Sciences of the United States of America

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Taxol induces the assembly of ...... centrosomes and kinetochores.

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P2093

De Brabander M

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De Mey J

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Geuens G

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Nuydens R

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P2860

Implications of treadmilling for the stability and polarity of actin and tubulin polymers in vivo

The effects of methyl (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl) carbamate, (R 17934; NSC 238159), a new synthetic antitumoral drug interfering with microtubules, on mammalian cells cultured in vitro

Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia.

Cytoplasmic microtubules in tissue culture cells appear to grow from an organizing structure towards the plasma membrane.

The role of three cytoplasmic fibers in BHK-21 cell motility. I. Microtubules and the effects of colchicine.

Tubulin and calmodulin. Effects of microtubule and microfilament inhibitors on localization in the mitotic apparatus.

Head-to-tail polymerization of microtubules in vitro. Electron microscope analysis of seeded assembly.

The pericentriolar material in Chinese hamster ovary cells nucleates microtubule formation.

Taxol stabilizes microtubules in mouse fibroblast cells

Quantitative initiation of microtubule assembly by chromosomes from Chinese hamster ovary cells.

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6117858

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348802

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