Identification of CD22 ligands on bone marrow sinusoidal endothelium implicated in CD22-dependent homing of recirculating B cells.
about
Siglecs in the immune systemTranscriptional programs of lymphoid tissue capillary and high endothelium reveal control mechanisms for lymphocyte homingCD22: an inhibitory enigmaAlpha2,6-sialic acid on platelet endothelial cell adhesion molecule (PECAM) regulates its homophilic interactions and downstream antiapoptotic signaling.Targeting CD22 with the monoclonal antibody epratuzumab modulates human B-cell maturation and cytokine production in response to Toll-like receptor 7 (TLR7) and B-cell receptor (BCR) signalingIn situ trans ligands of CD22 identified by glycan-protein photocross-linking-enabled proteomics.New functions for the sialic acid-binding adhesion molecule CD22, a member of the growing family of Siglecs.Interaction of platelet endothelial cell adhesion molecule (PECAM) with α2,6-sialylated glycan regulates its cell surface residency and anti-apoptotic role.CD19, CD21, and CD22: multifaceted response regulators of B lymphocyte signal transduction.Epratuzumab targeting of CD22 affects adhesion molecule expression and migration of B-cells in systemic lupus erythematosus.Isotype control of B cell signaling.Homing of antibody secreting cells.Recombinant immunotoxins for the treatment of haematological malignancies.A coordinated change in chemokine responsiveness guides plasma cell movementsUnmasking of CD22 Co-receptor on Germinal Center B-cells Occurs by Alternative Mechanisms in Mouse and Man.How influenza's neuraminidase promotes virulence and creates localized lung mucosa immunodeficiency.CD22 is required for protection against West Nile virus Infection.A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models.Homing imprinting and immunomodulation in the gut: role of dendritic cells and retinoids.CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca2+ signaling.CD22 expression mediates the regulatory functions of peritoneal B-1a cells during the remission phase of contact hypersensitivity reactionsFoxo3-/- mice demonstrate reduced numbers of pre-B and recirculating B cells but normal splenic B cell sub-population distribution.Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node.Natural ligands for CD33-related Siglecs?The bone marrow perisinusoidal niche for recirculating B cells and the positive selection of bone marrow-derived B lymphocytes.Glycosylation in immune cell trafficking.Masking of CD22 by cis ligands does not prevent redistribution of CD22 to sites of cell contact.CD22 and autoimmune disease.Tissue specific heterogeneity in effector immune cell response.Tracking plasma cell differentiation and survival.CD22 and Siglec-G regulate inhibition of B-cell signaling by sialic acid ligand binding and control B-cell tolerance.Sweet role of platelet endothelial cell adhesion molecule in understanding angiogenesis.Adhesion Molecules: Master Controllers of the Circulatory System.Viewing Siglecs through the lens of tumor immunology.Human B-lymphocytes express alpha2-6-sialylated 6-sulfo-N-acetyllactosamine serving as a preferred ligand for CD22/Siglec-2.The pan-B cell marker CD22 is expressed on gastrointestinal eosinophils and negatively regulates tissue eosinophiliaThe ligand-binding domain of CD22 is needed for inhibition of the B cell receptor signal, as demonstrated by a novel human CD22-specific inhibitor compound.Regulation of B cell functions by the sialic acid-binding receptors siglec-G and CD22.CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms.Respiratory vaccination of mice against influenza virus: dissection of T- and B-cell priming functions.
P2860
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P2860
Identification of CD22 ligands on bone marrow sinusoidal endothelium implicated in CD22-dependent homing of recirculating B cells.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Identification of CD22 ligands ...... ming of recirculating B cells.
@ast
Identification of CD22 ligands ...... ming of recirculating B cells.
@en
type
label
Identification of CD22 ligands ...... ming of recirculating B cells.
@ast
Identification of CD22 ligands ...... ming of recirculating B cells.
@en
prefLabel
Identification of CD22 ligands ...... ming of recirculating B cells.
@ast
Identification of CD22 ligands ...... ming of recirculating B cells.
@en
P2093
P2860
P356
P1476
Identification of CD22 ligands ...... ming of recirculating B cells.
@en
P2093
P2860
P304
P356
10.1084/JEM.189.9.1513
P407
P577
1999-05-01T00:00:00Z