A sequential mechanism for exosite-mediated factor IX activation by factor XIa
about
Factor XI as a target for antithrombotic therapyFactor XI and contact activation as targets for antithrombotic therapyThe mechanism underlying activation of factor IX by factor XIa.Analysis of the factor XI variant Arg184Gly suggests a structural basis for factor IX binding to factor XIaAllosteric inhibition of human factor XIa: discovery of monosulfated benzofurans as a class of promising inhibitorsFactor XI anion-binding sites are required for productive interactions with polyphosphate.Evidence for factor IX-independent roles for factor XIa in blood coagulation.Factor XII inhibition reduces thrombus formation in a primate thrombosis model.Measurement of factor IX activity in plasma-derived and recombinant concentrates: insights from thrombin generation and activation-based assays.An update on factor XI structure and function.Generation and characterization of aptamers targeting factor XIa.
P2860
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P2860
A sequential mechanism for exosite-mediated factor IX activation by factor XIa
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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name
A sequential mechanism for exosite-mediated factor IX activation by factor XIa
@ast
A sequential mechanism for exosite-mediated factor IX activation by factor XIa
@en
type
label
A sequential mechanism for exosite-mediated factor IX activation by factor XIa
@ast
A sequential mechanism for exosite-mediated factor IX activation by factor XIa
@en
prefLabel
A sequential mechanism for exosite-mediated factor IX activation by factor XIa
@ast
A sequential mechanism for exosite-mediated factor IX activation by factor XIa
@en
P2093
P2860
P356
P1476
A sequential mechanism for exosite-mediated factor IX activation by factor XIa
@en
P2093
Amanda Messer
David Gailani
Mao-fu Sun
S Paul Bajaj
Stephen B Smith
Yipeng Geng
P2860
P304
38200-38209
P356
10.1074/JBC.M112.376343
P407
P577
2012-09-07T00:00:00Z