Active immunization against the vascular endothelial growth factor receptor flk1 inhibits tumor angiogenesis and metastasis. - Wikidata - awgldk - TriplyDB

Active immunization against the vascular endothelial growth factor receptor flk1 inhibits tumor angiogenesis and metastasis.

Active immunization against the vascular endothelial growth factor receptor flk1 inhibits tumor angiogenesis and metastasis.

http://www.wikidata.org/entity/Q36369761

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A DNA vaccine targeting angiomotin inhibits angiogenesis and suppresses tumor growth Cancer anti-angiogenesis vaccines: Is the tumor vasculature antigenically unique?Molecular testing in lung cancer in the era of precision medicine Targeting the tumor vasculature to enhance T cell activity Acetylbritannilactone Modulates Vascular Endothelial Growth Factor Signaling and Regulates Angiogenesis in Endothelial Cells An anti-vascular endothelial growth factor receptor 2/fetal liver kinase-1 Listeria monocytogenes anti-angiogenesis cancer vaccine for the treatment of primary and metastatic Her-2/neu+ breast tumors in a mouse model.CD8 T-cell induction against vascular endothelial growth factor receptor 2 by Salmonella for vaccination purposes against a murine melanoma Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice Double-blind, placebo-controlled first in human study to investigate an oral vaccine aimed to elicit an immune reaction against the VEGF-Receptor 2 in patients with stage IV and locally advanced pancreatic cancer.Vaccines targeting the neovasculature of tumors Interleukin-12 inhibits tumor growth in a novel angiogenesis canine hemangiosarcoma xenograft model.Murine Lewis lung carcinoma-derived endothelium expresses markers of endothelial activation and requires tumor-specific extracellular matrix in vitro.Targeting angiogenesis in melanoma: prospects for the future Angiogenesis, lymphangiogenesis, and melanoma metastasis.Vaccines targeting tumor blood vessel antigens promote CD8(+) T cell-dependent tumor eradication or dormancy in HLA-A2 transgenic mice Antigenic targets for renal cell carcinoma immunotherapy.Antisense therapy for restenosis following percutaneous coronary intervention.Immunotherapy of malignant brain tumors.T cell-mediated immunotherapy of metastases: state of the art in 2005.Stabilization of HIF-2α induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth in a murine melanoma model.Cancer microenvironment and cancer vaccine.Effects of the tumor microenvironment on the efficacy of tumor immunotherapy.Phase I clinical trial of human vascular endothelial growth factor receptor 1 peptide vaccines for patients with metastatic renal cell carcinoma.Angiogenesis in chronic obstructive pulmonary disease: a translational appraisal Immunotherapy against angiogenesis-associated targets: evidence and implications for the treatment of malignant glioma.Angiogenesis in cutaneous malignant melanoma and potential therapeutic strategies.Tumor endothelial marker 1-specific DNA vaccination targets tumor vasculature.Blood vessel maturation, vascular phenotype and angiogenic potential in malignant melanoma: one step forward for overcoming anti-angiogenic drug resistance?Targeted therapy in renal cancer.Physiological and pathological angiogenesis in the adult pulmonary circulation.Angiogenesis, vasculogenic mimicry and vascular invasion in cutaneous malignant melanoma - implications for therapeutic strategies and targeted therapies.Mouse tumor vasculature expresses NKG2D ligands and can be targeted by chimeric NKG2D-modified T cells.Fine-Tuning Tumor Endothelial Cells to Selectively Kill Cancer.Combination of recombinant xenogeneic endoglin DNA and protein vaccination enhances anti-tumor effects.Inhibition of B16 melanoma growth and metastasis in C57BL mice by vaccination with a syngeneic endothelial cell line.A DNA vaccine against extracellular domains 1-3 of flk-1 and its immune preventive and therapeutic effects against H22 tumor cell in vivo.A novel kinase mutation in VEGFR-1 predisposes its αC-helix/activation loop towards allosteric activation: Atomic insights from protein simulation.Antitumor immunity induced by VE-cadherin modified DC vaccine.Inhibition of angiogenesis by a Semliki Forest virus vector expressing VEGFR-2 reduces tumour growth and metastasis in mice.Evaluation of a xenogeneic vascular endothelial growth factor-2 vaccine in two preclinical metastatic tumor models in mice.

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P2860

Active immunization against the vascular endothelial growth factor receptor flk1 inhibits tumor angiogenesis and metastasis.

http://www.wikidata.org/entity/Q36369761

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Active immunization against th ...... r angiogenesis and metastasis.

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Active immunization against th ...... r angiogenesis and metastasis.

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Active immunization against th ...... r angiogenesis and metastasis.

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Journal of Experimental Medicine

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Active immunization against th ...... r angiogenesis and metastasis.

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Andrea T Hooper

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Angel Santiago

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Daniel J Hicklin

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Haijun Sun

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Hongli Li

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Karen D King

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Mei-Nai Wang

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Peter Bohlen

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Rajiv Bassi

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Yiwen Li

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P2860

Human tumor antigens recognized by T lymphocytes

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

What is the evidence that tumors are angiogenesis dependent?

Expression and function of angiopoietin-1 in breast cancer.

Expression of vascular endothelial growth factor receptors 1, 2 and 3 in placentas from normal and complicated pregnancies.

Inhibition of vascular endothelial growth factor-induced receptor activation with anti-kinase insert domain-containing receptor single-chain antibodies from a phage display library.

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1575-1584

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10.1084/JEM.20020072

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12

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195

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236244335

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12070285

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2193561

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