Cytosolic phospholipase A2alpha-deficient mice are resistant to collagen-induced arthritis - Wikidata - awgldk - TriplyDB

Cytosolic phospholipase A2alpha-deficient mice are resistant to collagen-induced arthritis

Cytosolic phospholipase A2alpha-deficient mice are resistant to collagen-induced arthritis

http://www.wikidata.org/entity/Q36370405

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Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention Potential Antifungal Targets against a Candida Biofilm Based on an Enzyme in the Arachidonic Acid Cascade-A Review Phospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizations A novel anti-inflammatory role for secretory phospholipase A2 in immune complex-mediated arthritis.Cytosolic phospholipase A2 regulates TNF-induced production of joint destructive effectors in synoviocytes.Cytosolic phospholipase A2α is critical for angiotensin II-induced hypertension and associated cardiovascular pathophysiology.Cytosolic phospholipase A(2)α protects against ischemia/reperfusion injury in the heart.Host cytosolic phospholipase A₂α contributes to group B Streptococcus penetration of the blood-brain barrier.The RNA-binding protein HuR stabilizes cytosolic phospholipase A2α mRNA under interleukin-1β treatment in non-small cell lung cancer A549 Cells Cytosolic phospholipase A2 modulates TLR2 signaling in synoviocytes Study of the role of cytosolic phospholipase A2 alpha in eicosanoid generation and thymocyte maturation in the thymus Identifying a major locus that regulates spontaneous arthritis in IL-1ra-deficient mice and analysis of potential candidates Cytosolic phospholipase A₂: physiological function and role in disease.cPLA(2)α gene activation by IL-1β is dependent on an upstream kinase pathway, enzymatic activation and downstream 15-lipoxygenase activity: a positive feedback loop Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis.Rheumatic diseases: the effects of inflammation on bone.An essential role of cytosolic phospholipase A2alpha in prostaglandin E2-mediated bone resorption associated with inflammation Cytosolic phospholipase A2 alpha-deficient mice are resistant to experimental autoimmune encephalomyelitis.Roles of cPLA2alpha and arachidonic acid in cancer Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase Ca2+ activation of the cPLA2 C2 domain: ordered binding of two Ca2+ ions with positive cooperativity.Characterization of eicosanoid synthesis in a genetic ablation model of ceramide kinase Membrane and inhibitor interactions of intracellular phospholipases A2.Regulation of Wnt/beta-catenin pathway by cPLA2alpha and PPARdelta A distinctive role of the leukotriene B4 receptor BLT1 in osteoclastic activity during bone loss.Low molecular weight hyaluronan activates cytosolic phospholipase A2α and eicosanoid production in monocytes and macrophages.HO-1 induction by CO-RM2 attenuates TNF-α-induced cytosolic phospholipase A2 expression via inhibition of PKCα-dependent NADPH oxidase/ROS and NF-κB.Targeting monocytes/macrophages in the treatment of rheumatoid arthritis.Persisting eicosanoid pathways in rheumatic diseases.Molecular characterisation of group IVA (cytosolic) phospholipase A2 in murine osteoblastic MC3T3-E1 cells.Interleukin-32 positively regulates radiation-induced vascular inflammation.Activation of cytosolic phospholipase A2alpha through nitric oxide-induced S-nitrosylation. Involvement of inducible nitric-oxide synthase and cyclooxygenase-2.Membrane-docking loops of the cPLA2 C2 domain: detailed structural analysis of the protein-membrane interface via site-directed spin-labeling.Cytosolic phospholipase A2 Group IValpha but not secreted phospholipase A2 Group IIA, V, or X induces interleukin-8 and cyclooxygenase-2 gene and protein expression through peroxisome proliferator-activated receptors gamma 1 and 2 in human lung cell Cysteinyl leukotrienes as novel host factors facilitating Cryptococcus neoformans penetration into the brain.Mechanism of glutamine inhibition of cytosolic phospholipase a2 (cPLA2 ): Evidence of physical interaction between glutamine-Induced mitogen-activated protein kinase phosphatase-1 and cPLA2.Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect TLR-4 mediated group IVA phospholipase A(2) activation is phosphatidic acid phosphohydrolase 1 and protein kinase C dependent.Targeting leukotriene B4 in inflammation.Genomic dissection and prioritizing of candidate genes of QTL for regulating spontaneous arthritis on chromosome 1 in mice deficient for interleukin-1 receptor antagonist.

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Cytosolic phospholipase A2alpha-deficient mice are resistant to collagen-induced arthritis

http://www.wikidata.org/entity/Q36370405

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2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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2003年學術文章

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name

Cytosolic phospholipase A2alph ...... to collagen-induced arthritis

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Cytosolic phospholipase A2alph ...... to collagen-induced arthritis

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type

label

Cytosolic phospholipase A2alph ...... to collagen-induced arthritis

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Cytosolic phospholipase A2alph ...... to collagen-induced arthritis

@en

prefLabel

Cytosolic phospholipase A2alph ...... to collagen-induced arthritis

@ast

Cytosolic phospholipase A2alph ...... to collagen-induced arthritis

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Journal of Experimental Medicine

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Cytosolic phospholipase A2alph ...... to collagen-induced arthritis

@en

P2093

Cheryl L Nickerson-Nutter

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James D Clark

http://www.w3.org/2001/XMLSchema#string

Kazuhiko Kume

http://www.w3.org/2001/XMLSchema#string

Linhong Sun

http://www.w3.org/2001/XMLSchema#string

Martin Hegen

http://www.w3.org/2001/XMLSchema#string

Mary E Goad

http://www.w3.org/2001/XMLSchema#string

Naonori Uozumi

http://www.w3.org/2001/XMLSchema#string

Takao Shimizu

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P2860

Molecular characterization of cytosolic phospholipase A2-beta

Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals

A novel calcium-independent phospholipase A2, cPLA2-gamma, that is prenylated and contains homology to cPLA2

A novel cytosolic calcium-independent phospholipase A2 contains eight ankyrin motifs

Impaired bone resorption to prostaglandin E2 in prostaglandin E receptor EP4-knockout mice

Polyunsaturated fatty acids and rheumatoid arthritis.

Dietary polyunsaturated fatty acids and inflammatory mediator production.

Leukotriene B4 plays a critical role in the progression of collagen-induced arthritis.

Increased expression of human type IIa secretory phospholipase A2 antigen in arthritic synovium.

Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates

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1297-1302

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10.1084/JEM.20030016

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10

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197

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2003-05-12T00:00:00Z

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10763644

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12743172

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2193788

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