Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase.
about
Disturbances of apoptotic cell clearance in systemic lupus erythematosusHeterogeneous nuclear ribonucleoprotein P2 is an autoantibody target in mice deficient for Mer, Axl, and Tyro3 receptor tyrosine kinasesThe C-mer gene is induced by Epstein-Barr virus immediate-early protein BRLF1PPAR-delta senses and orchestrates clearance of apoptotic cells to promote toleranceTIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.The clearance of dying cells: table for twoPhosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancerClearance Deficiency and Cell Death Pathways: A Model for the Pathogenesis of SLELinking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosusTyro3, Axl, and Mertk receptor signaling in inflammatory bowel disease and colitis-associated cancerThe impact of the myeloid response to radiation therapyIntracellular nucleic acid sensors and autoimmunityThe Role of TAM Family Receptors in Immune Cell Function: Implications for Cancer TherapyThe Gas6/TAM System and Multiple SclerosisLigand Activation of TAM Family Receptors-Implications for Tumor Biology and Therapeutic ResponseChemerin peptides promote phagocytosis in a ChemR23- and Syk-dependent mannerApoptotic cell responses in the splenic marginal zone: a paradigm for immunologic reactions to apoptotic antigens with implications for autoimmunityContribution of Defective PS Recognition and Efferocytosis to Chronic Inflammation and AutoimmunityRole of Gas6 in erythropoiesis and anemia in miceThe Drosophila TRPP cation channel, PKD2 and Dmel/Ced-12 act in genetically distinct pathways during apoptotic cell clearancePolymorphisms in the receptor tyrosine kinase MERTK gene are associated with multiple sclerosis susceptibilityClearance of Dying Cells by Phagocytes: Mechanisms and Implications for Disease Pathogenesis.Clearance of apoptotic cells: implications in health and diseaseApoptotic human cells inhibit migration of granulocytes via release of lactoferrin.Autoimmune kidney disease and impaired engulfment of apoptotic cells in mice with macrophage peroxisome proliferator-activated receptor gamma or retinoid X receptor alpha deficiency.The role of B cells in lupus pathogenesis.Epithelial cell-directed efferocytosis in the post-partum mammary gland is necessary for tissue homeostasis and future lactationImmunobiology of the TAM receptors.Abnormal production of pro- and anti-inflammatory cytokines by lupus monocytes in response to apoptotic cells.Increased hematopoietic cells in the mertk-/- mouse peritoneal cavity: a result of augmented migrationDendritic cells in systemic lupus erythematosusInnate apoptotic immunity: the calming touch of death.Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus.Apoptotic cell-based therapies against transplant rejection: role of recipient's dendritic cells.Toll-like receptor 7 (TLR7) modulates anti-nucleosomal autoantibody isotype and renal complement deposition in mice exposed to syngeneic late apoptotic cells.p85α recruitment by the CD300f phosphatidylserine receptor mediates apoptotic cell clearance required for autoimmunity suppressionTAM receptor ligands in lupus: protein S but not Gas6 levels reflect disease activity in systemic lupus erythematosusDo follicular dendritic cells regulate lupus-specific B cells?Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacity.
P2860
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P2860
Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Delayed apoptotic cell clearan ...... -mer membrane tyrosine kinase.
@ast
Delayed apoptotic cell clearan ...... -mer membrane tyrosine kinase.
@en
type
label
Delayed apoptotic cell clearan ...... -mer membrane tyrosine kinase.
@ast
Delayed apoptotic cell clearan ...... -mer membrane tyrosine kinase.
@en
prefLabel
Delayed apoptotic cell clearan ...... -mer membrane tyrosine kinase.
@ast
Delayed apoptotic cell clearan ...... -mer membrane tyrosine kinase.
@en
P2093
P2860
P356
P1476
Delayed apoptotic cell clearan ...... -mer membrane tyrosine kinase.
@en
P2093
Elizabeth A Reap
Glenn Matsushima
H Shelton Earp
J Charles Jennette
Philip L Cohen
Robert A S Roubey
Roberto Caricchio
Todd D Camenisch
Valsamma Abraham
P2860
P304
P356
10.1084/JEM.20012094
P407
P577
2002-07-01T00:00:00Z