Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase. - Wikidata - awgldk - TriplyDB

Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase.

Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase.

http://www.wikidata.org/entity/Q36371130

about

Disturbances of apoptotic cell clearance in systemic lupus erythematosus Heterogeneous nuclear ribonucleoprotein P2 is an autoantibody target in mice deficient for Mer, Axl, and Tyro3 receptor tyrosine kinases The C-mer gene is induced by Epstein-Barr virus immediate-early protein BRLF1 PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.The clearance of dying cells: table for two Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer Clearance Deficiency and Cell Death Pathways: A Model for the Pathogenesis of SLE Linking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosus Tyro3, Axl, and Mertk receptor signaling in inflammatory bowel disease and colitis-associated cancer The impact of the myeloid response to radiation therapy Intracellular nucleic acid sensors and autoimmunity The Role of TAM Family Receptors in Immune Cell Function: Implications for Cancer Therapy The Gas6/TAM System and Multiple Sclerosis Ligand Activation of TAM Family Receptors-Implications for Tumor Biology and Therapeutic Response Chemerin peptides promote phagocytosis in a ChemR23- and Syk-dependent manner Apoptotic cell responses in the splenic marginal zone: a paradigm for immunologic reactions to apoptotic antigens with implications for autoimmunity Contribution of Defective PS Recognition and Efferocytosis to Chronic Inflammation and Autoimmunity Role of Gas6 in erythropoiesis and anemia in mice The Drosophila TRPP cation channel, PKD2 and Dmel/Ced-12 act in genetically distinct pathways during apoptotic cell clearance Polymorphisms in the receptor tyrosine kinase MERTK gene are associated with multiple sclerosis susceptibility Clearance of Dying Cells by Phagocytes: Mechanisms and Implications for Disease Pathogenesis.Clearance of apoptotic cells: implications in health and disease Apoptotic human cells inhibit migration of granulocytes via release of lactoferrin.Autoimmune kidney disease and impaired engulfment of apoptotic cells in mice with macrophage peroxisome proliferator-activated receptor gamma or retinoid X receptor alpha deficiency.The role of B cells in lupus pathogenesis.Epithelial cell-directed efferocytosis in the post-partum mammary gland is necessary for tissue homeostasis and future lactation Immunobiology of the TAM receptors.Abnormal production of pro- and anti-inflammatory cytokines by lupus monocytes in response to apoptotic cells.Increased hematopoietic cells in the mertk-/- mouse peritoneal cavity: a result of augmented migration Dendritic cells in systemic lupus erythematosus Innate apoptotic immunity: the calming touch of death.Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus.Apoptotic cell-based therapies against transplant rejection: role of recipient's dendritic cells.Toll-like receptor 7 (TLR7) modulates anti-nucleosomal autoantibody isotype and renal complement deposition in mice exposed to syngeneic late apoptotic cells.p85α recruitment by the CD300f phosphatidylserine receptor mediates apoptotic cell clearance required for autoimmunity suppression TAM receptor ligands in lupus: protein S but not Gas6 levels reflect disease activity in systemic lupus erythematosus Do follicular dendritic cells regulate lupus-specific B cells?Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacity.

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P2860

Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase.

http://www.wikidata.org/entity/Q36371130

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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2002年學術文章

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2002年學術文章

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name

Delayed apoptotic cell clearan ...... -mer membrane tyrosine kinase.

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Delayed apoptotic cell clearan ...... -mer membrane tyrosine kinase.

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Delayed apoptotic cell clearan ...... -mer membrane tyrosine kinase.

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Delayed apoptotic cell clearan ...... -mer membrane tyrosine kinase.

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Journal of Experimental Medicine

P1476

Delayed apoptotic cell clearan ...... -mer membrane tyrosine kinase.

@en

P2093

Elizabeth A Reap

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Glenn Matsushima

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H Shelton Earp

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J Charles Jennette

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Philip L Cohen

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Robert A S Roubey

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Roberto Caricchio

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Todd D Camenisch

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Valsamma Abraham

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P2860

Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family

A receptor for phosphatidylserine-specific clearance of apoptotic cells

Regulation of macrophage cytokine production by phagocytosis of apoptotic and post-apoptotic cells.

Phagocytosis and clearance of apoptotic cells is mediated by MER.

Remnants of suicidal cells fostering systemic autoaggression. Apoptosis in the origin and maintenance of autoimmunity.

Identification of Gas6 as a growth factor for human Schwann cells.

Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences.

Dendritic cells cross-present latency gene products from Epstein-Barr virus-transformed B cells and expand tumor-reactive CD8(+) killer T cells

The role of B cell abnormalities in the systemic autoimmune syndromes of lpr and gld mice.

Dendritic cell presentation of antigens from apoptotic cells in a proinflammatory context: role of opsonizing anti-beta2-glycoprotein I antibodies.

P304

135-140

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10.1084/JEM.20012094

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1

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196

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236245617

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12093878

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apoptotic process

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2194017

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