Selection at multiple checkpoints focuses V(H)12 B cell differentiation toward a single B-1 cell specificity
about
Autoreactivity by design: innate B and T lymphocytesCD1-restricted T-cell responses and microbial infection.Positive selection focuses the VH12 B-cell repertoire towards a single B1 specificity with survival function.Selection during development of VH11+ B cells: a model for natural autoantibody-producing CD5+ B cells.The mouse CD1d-restricted repertoire is dominated by a few autoreactive T cell receptor families.Expression of plasma cell alloantigen 1 defines layered development of B-1a B-cell subsets with distinct innate-like functions.A new site-directed transgenic rheumatoid factor mouse model demonstrates extrafollicular class switch and plasmablast formationThe skewed heavy-chain repertoire in peritoneal B-1 cells is predetermined by the selection via pre-B cell receptor during B cell ontogeny in the fetal liver.Btk regulates multiple stages in the development and survival of B-1 cells.
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Selection at multiple checkpoints focuses V(H)12 B cell differentiation toward a single B-1 cell specificity
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1999 nî lūn-bûn
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1999年の論文
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1999年学术文章
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1999年学术文章
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Selection at multiple checkpoi ...... a single B-1 cell specificity
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Selection at multiple checkpoi ...... a single B-1 cell specificity
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Selection at multiple checkpoi ...... a single B-1 cell specificity
@ast
Selection at multiple checkpoi ...... a single B-1 cell specificity
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prefLabel
Selection at multiple checkpoi ...... a single B-1 cell specificity
@ast
Selection at multiple checkpoi ...... a single B-1 cell specificity
@en
P2093
P2860
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Selection at multiple checkpoi ...... a single B-1 cell specificity
@en
P2093
P2860
P304
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10.1084/JEM.190.7.903
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1999-10-01T00:00:00Z