The Src family tyrosine kinase Fyn regulates natural killer T cell development.
about
The role of NKT cells in tumor immunityThe BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functionsAntitumor Responses of Invariant Natural Killer T CellsLarge granular lymphocytosis during dasatinib therapyCD36 and Fyn kinase mediate malaria-induced lung endothelial barrier dysfunction in mice infected with Plasmodium berghei'Srcasm: a novel Src activating and signaling moleculeHomotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage developmentCritical roles of RasGRP1 for invariant NKT cell developmentIL-15 regulates homeostasis and terminal maturation of NKT cellsCommitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogenyTranscriptional control of invariant NKT cell development.Disposal of iNKT cell deficiency and an increase in expression of SLAM signaling factors characterizes sarcoidosis remission: a 4-year longitudinal study.Interleukin-2-inducible T cell kinase (Itk) network edge dependence for the maturation of iNKT cell.Temporal differences in the dependency on phosphoinositide-dependent kinase 1 distinguish the development of invariant Valpha14 NKT cells and conventional T cellsDifferential requirements for the Ets transcription factor Elf-1 in the development of NKT cells and NK cellsMolecular and immunological basis of X-linked lymphoproliferative disease.Innate self recognition by an invariant, rearranged T-cell receptor and its immune consequences.Tight regulation of diacylglycerol-mediated signaling is critical for proper invariant NKT cell development.Surface T-cell antigen receptor expression and availability for long-term antigenic signaling.The split personality of NKT cells in malignancy, autoimmune and allergic disordersGenetic control of NKT cell numbers.Molecular and cellular pathogenesis of X-linked lymphoproliferative disease.Signaling for NKT cell development: the SAP-FynT connectionBiochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation.A privileged view of NKT cells and peripheral tolerance through the eye.A natural killer T (NKT) cell developmental pathway iInvolving a thymus-dependent NK1.1(-)CD4(+) CD1d-dependent precursor stage.CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cellsDefective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product.Characterization of the early stages of thymic NKT cell development.Regulation of natural cytotoxicity by the adaptor SAP and the Src-related kinase Fyn.Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes.Immune regulation by SLAM family receptors and SAP-related adaptors.Src protein tyrosine kinase family and acute inflammatory responses.SAP expression in T cells, not in B cells, is required for humoral immunity.Selection of self-reactive T cells in the thymus.Requirements for selection of conventional and innate T lymphocyte lineages.NK cell regulation by SLAM family receptors and SAP-related adapters.The transcriptional repressor NKAP is required for the development of iNKT cellsFyn deficiency promotes a preferential increase in subcutaneous adipose tissue mass and decreased visceral adipose tissue inflammation.Does the developmental status of Valpha14i NKT cells play a role in disease?
P2860
Q24648939-A6F1D267-577F-4467-9E7B-C4ECDF0E01C2Q24650707-0CF2AD17-FF2D-4C89-A19D-29AACF75C73AQ26778648-E948BFCD-2D7E-4045-9C10-AB212B3C248EQ27012699-9FEB1D27-4384-43C9-B692-960C54FB9B33Q27309911-234B4890-CBE3-42FD-A06B-4B2415EC660AQ28505622-EE1CB6AA-EA04-4657-BDC5-69097176F10EQ28584820-1D463524-4C12-44BF-8563-5E1F65922081Q28591678-29A351A7-93CD-487C-89F6-013474E2651CQ28741430-6DE14301-1052-4096-A078-A8545F2666F9Q33935873-F12B8B0A-57BC-4D3F-9A3D-0C5F581029A4Q34248566-B71B782F-AF38-4328-89DC-0891E14CA963Q34270878-0D69176E-D70B-4F74-9804-B50063A4A3A6Q34452458-EC6323AA-BE68-48FB-AAB3-CC9AE63E445FQ34459964-785D8D76-16FF-4709-83C4-618C8B830F58Q34667733-112DEC1A-B8A9-43FC-821A-D8016F817FA1Q35096711-2B0AFEE4-1B99-4827-9B31-44BE28990B51Q35131643-B98E1A75-C1C5-4BD2-81A8-7277C04AD7B5Q35175941-2C79FA89-B37A-4D32-A2A9-D53A3F33DD6DQ35583489-7A6C9BD8-FF6E-4CF2-8984-4D7F7DDBC048Q35590727-9BA08E1C-BF5A-4606-A946-8CB4F08CCEE2Q35798141-4A86AA06-90F1-47BB-B78E-DFB894704C13Q36015040-8D19B4D9-7A5B-4D0A-A593-8E2E81729E6BQ36076597-8611F689-CDBA-4679-A2FA-6FDB099AFA0AQ36174537-6CE5512A-66DE-4DAE-B41B-39D849FD0028Q36194819-8FE40084-997C-4E88-80B2-799BDB0BE4DFQ36370202-7F8DF824-147B-4E9B-A032-AC5FBECA2935Q36370736-05C26C59-873A-4119-95B1-DEADD965F171Q36402758-93DCD56A-AB1C-4532-9A37-CC5EE8C9F39EQ36402797-42E3C854-DC5D-4DAC-A949-ACA6541633F1Q36402936-E9AA61FE-3F02-4126-9313-0FAECB029F9DQ36403175-E70938EB-36F1-4106-ACC8-FDB8A7C76E30Q36403407-1C72C165-B8AA-4AD8-A471-5D2C6F27E7C6Q36438267-1A15EBE0-3CA9-4F55-B22D-1CBCCEC6B580Q36446175-C59E73DB-CDA1-4D21-A6C2-8A8A34011C1FQ36456282-496E2D78-8F36-4021-9947-A8538643F019Q36648754-40F97A5E-815C-4AA1-B6DF-8F65DEDCEAD6Q36652149-4376A89B-B41C-42FC-9923-CA0612F1F1F7Q36737300-09D8BEC2-A270-4133-8195-A69D5C9E257EQ36795964-14E83364-7966-4C48-8A71-91F93C1F083BQ36799673-BF913766-08A2-4E82-B72B-A2EF2BB0076C
P2860
The Src family tyrosine kinase Fyn regulates natural killer T cell development.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
The Src family tyrosine kinase Fyn regulates natural killer T cell development.
@ast
The Src family tyrosine kinase Fyn regulates natural killer T cell development.
@en
type
label
The Src family tyrosine kinase Fyn regulates natural killer T cell development.
@ast
The Src family tyrosine kinase Fyn regulates natural killer T cell development.
@en
prefLabel
The Src family tyrosine kinase Fyn regulates natural killer T cell development.
@ast
The Src family tyrosine kinase Fyn regulates natural killer T cell development.
@en
P2860
P356
P1476
The Src family tyrosine kinase Fyn regulates natural killer T cell development.
@en
P2093
P2860
P304
P356
10.1084/JEM.190.8.1189
P407
P577
1999-10-01T00:00:00Z