A balance between positive and negative signals in cytotoxic lymphocytes regulates the polarization of lipid rafts during the development of cell-mediated killing
about
Human NKG2D-ligands: cell biology strategies to ensure immune recognitionCell surface organization of stress-inducible proteins ULBP and MICA that stimulate human NK cells and T cells via NKG2DAssociation of the X-linked lymphoproliferative disease gene product SAP/SH2D1A with 2B4, a natural killer cell-activating molecule, is dependent on phosphoinositide 3-kinaseFc gamma RIIB1/SHIP-mediated inhibitory signaling in B cells involves lipid rafts.Exclusion of lipid rafts and decreased mobility of CD94/NKG2A receptors at the inhibitory NK cell synapse.Intercellular transfer and supramolecular organization of human leukocyte antigen C at inhibitory natural killer cell immune synapses.Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses.Evidence for host genetic regulation of altered lipid metabolism in experimental toxoplasmosis supported with gene data mining results.Signaling at the inhibitory natural killer cell immune synapse regulates lipid raft polarization but not class I MHC clusteringFloating the raft hypothesis for immune receptors: access to rafts controls receptor signaling and trafficking.PD-1 expression on peripheral CD8+ TEM/TEMRA subsets closely correlated with HCV viral load in chronic hepatitis C patientsIntracellular signaling by the killer immunoglobulin-like receptors and Ly49.ITAMs versus ITIMs: striking a balance during cell regulation.Ras-related C3 Botulinum Toxin Substrate (Rac) and Src Family Kinases (SFK) Are Proximal and Essential for Phosphatidylinositol 3-Kinase (PI3K) Activation in Natural Killer (NK) Cell-mediated Direct Cytotoxicity against Cryptococcus neoformans.Human natural killer cell receptors and signal transduction.Molecular mechanisms for apoptosis induced by signaling through the B cell antigen receptor.The secretory synapse: the secrets of a serial killer.Visualization of signaling pathways and cortical cytoskeleton in cytolytic and noncytolytic natural killer cell immune synapses.Imaging immune surveillance by T cells and NK cells.The roles of membrane microdomains (rafts) in T cell activation.Regulation of lymphocyte-mediated killing by GTP-binding proteins.Stable masking by H-2Dd cis ligand limits Ly49A relocalization to the site of NK cell/target cell contact.Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin-like receptors.Microclusters of inhibitory killer immunoglobulin-like receptor signaling at natural killer cell immunological synapsesSignaling pathways in aged T cells - a reflection of T cell differentiation, cell senescence and host environment.Natural killer cell inhibitory receptors block actin cytoskeleton-dependent recruitment of 2B4 (CD244) to lipid rafts.Vav1 phosphorylation is induced by beta2 integrin engagement on natural killer cells upstream of actin cytoskeleton and lipid raft reorganization.Colocalization of the IL-12 receptor and FcgammaRIIIa to natural killer cell lipid rafts leads to activation of ERK and enhanced production of interferon-gammaDendritic cell and natural killer cell cross-talk: a pivotal role of CX3CL1 in NK cytoskeleton organization and activationDissecting the role of hyperthermia in natural killer cell mediated anti-tumor responses.The killer's kiss: the many functions of NK cell immunological synapses.Dynamics of natural killer cell receptor revealed by quantitative analysis of photoswitchable protein.Formation and function of the lytic NK-cell immunological synapse.Endocytosis and intracellular trafficking of human natural killer cell receptorsSignificant functional heterogeneity among KIR2DL1 alleles and a pivotal role of arginine 245.Understanding natural killer cell regulation by mathematical approachesRecruitment of activating NK-cell receptors 2B4 and NKG2D to membrane microdomains in mammalian cells is dependent on their transmembrane regions.L-plastin is involved in NKG2D recruitment into lipid rafts and NKG2D-mediated NK cell migration.CD40 translocation to lipid rafts: signaling requirements and downstream biological events.Cross-linking of MHC class I molecules on human NK cells inhibits NK cell function, segregates MHC I from the NK cell synapse, and induces intracellular phosphotyrosines.
P2860
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P2860
A balance between positive and negative signals in cytotoxic lymphocytes regulates the polarization of lipid rafts during the development of cell-mediated killing
description
2000 nî lūn-bûn
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2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
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2000年學術文章
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2000年學術文章
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name
A balance between positive and ...... pment of cell-mediated killing
@ast
A balance between positive and ...... pment of cell-mediated killing
@en
type
label
A balance between positive and ...... pment of cell-mediated killing
@ast
A balance between positive and ...... pment of cell-mediated killing
@en
prefLabel
A balance between positive and ...... pment of cell-mediated killing
@ast
A balance between positive and ...... pment of cell-mediated killing
@en
P2093
P2860
P356
P1476
A balance between positive and ...... pment of cell-mediated killing
@en
P2093
D D Billadeau
D Jevremovic
P J Leibson
P2860
P304
P356
10.1084/JEM.191.2.347
P407
P577
2000-01-01T00:00:00Z