Linking vascular disorders and Alzheimer's disease: potential involvement of BACE1
about
Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.β-Secretase-1 elevation in aged monkey and Alzheimer's disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and β-amyloid accumulation.A common BACE1 polymorphism is a risk factor for sporadic Creutzfeldt-Jakob diseaseTranscranial doppler ultrasound blood flow velocity and pulsatility index as systemic indicators for Alzheimer's diseaseOxidative stress affects processing of amyloid precursor protein in vascular endothelial cellsIntranasal therapeutic strategies for management of Alzheimer's disease.Early Growth Response 1 (Egr-1) Is a Transcriptional Activator of β-Secretase 1 (BACE-1) in the BrainMicroRNA-195 prevents dendritic degeneration and neuron death in rats following chronic brain hypoperfusion.Hypoxic stress, brain vascular system, and β-amyloid: a primary cell culture study.Chronic Sleep Restriction Induces Cognitive Deficits and Cortical Beta-Amyloid Deposition in Mice via BACE1-Antisense Activation.Activation of Cdk5/p25 and tau phosphorylation following chronic brain hypoperfusion in rats involves microRNA-195 down-regulation.Increased BACE1-AS long noncoding RNA and β-amyloid levels in heart failure.
P2860
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P2860
Linking vascular disorders and Alzheimer's disease: potential involvement of BACE1
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Linking vascular disorders and Alzheimer's disease: potential involvement of BACE1
@ast
Linking vascular disorders and Alzheimer's disease: potential involvement of BACE1
@en
type
label
Linking vascular disorders and Alzheimer's disease: potential involvement of BACE1
@ast
Linking vascular disorders and Alzheimer's disease: potential involvement of BACE1
@en
prefLabel
Linking vascular disorders and Alzheimer's disease: potential involvement of BACE1
@ast
Linking vascular disorders and Alzheimer's disease: potential involvement of BACE1
@en
P2860
P1476
Linking vascular disorders and Alzheimer's disease: potential involvement of BACE1
@en
P2093
Robert Vassar
Sarah L Cole
P2860
P304
P356
10.1016/J.NEUROBIOLAGING.2007.12.012
P577
2008-03-04T00:00:00Z