Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells - Wikidata - awgldk - TriplyDB

Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells

Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells

http://www.wikidata.org/entity/Q36378400

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Down syndrome and leukemia: insights into leukemogenesis and translational targets Concise Review: Methods and Cell Types Used to Generate Down Syndrome Induced Pluripotent Stem Cells Modelling human disease with pluripotent stem cells The emerging role of GATA transcription factors in development and disease A System to Study Aneuploidy In Vivo Transient Abnormal Myelopoiesis and AML in Down Syndrome: an Update Concise Review: Induced Pluripotent Stem Cells as New Model Systems in Oncology Differentiation Pathway Neonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition.Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients.GATA factor mutations in hematologic disease.The prenatal origins of cancer Integrated differential transcriptome maps of Acute Megakaryoblastic Leukemia (AMKL) in children with or without Down Syndrome (DS)Identification of a DNA methylation signature in blood cells from persons with Down Syndrome.Pluripotent stem cells reveal erythroid-specific activities of the GATA1 N-terminus.Distinct gene expression program dynamics during erythropoiesis from human induced pluripotent stem cells compared with adult and cord blood progenitors.Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells.Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21 Brief report: isogenic induced pluripotent stem cell lines from an adult with mosaic down syndrome model accelerated neuronal ageing and neurodegeneration.Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia Ribosomal and hematopoietic defects in induced pluripotent stem cells derived from Diamond Blackfan anemia patients.The modern primitives: applying new technological approaches to explore the biology of the earliest red blood cells Erythropoietin critically regulates the terminal maturation of murine and human primitive erythroblasts.High-level transgene expression in induced pluripotent stem cell-derived megakaryocytes: correction of Glanzmann thrombasthenia.Induced pluripotent stem cells as a cellular model for studying Down Syndrome.GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia.Generation of iPS cells from normal and malignant hematopoietic cells.The impact of trisomy 21 on foetal haematopoiesis.Modeling neurodevelopmental disorders using human pluripotent stem cells.Haematopoietic development and leukaemia in Down syndrome.Stem and progenitor cell dysfunction in human trisomies.The potential of induced pluripotent stem cells in models of neurological disorders: implications on future therapy.Aneuploid embryonic stem cells exhibit impaired differentiation and increased neoplastic potential.Evolution of myeloid leukemia in children with Down syndrome.CD41 and CD45 expression marks the angioformative initiation of neovascularisation in human haemangioblastoma.Perturbations of heart development and function in cardiomyocytes from human embryonic stem cells with trisomy 21.Down syndrome and the complexity of genome dosage imbalance.Molecular Characterization of Down Syndrome Embryonic Stem Cells Reveals a Role for RUNX1 in Neural Differentiation.Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies.Cytokine-free directed differentiation of human pluripotent stem cells efficiently produces hemogenic endothelium with lymphoid potential.

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Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells

http://www.wikidata.org/entity/Q36378400

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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Trisomy 21-associated defects ...... induced pluripotent stem cells

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Trisomy 21-associated defects ...... induced pluripotent stem cells

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Trisomy 21-associated defects ...... induced pluripotent stem cells

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Trisomy 21-associated defects ...... induced pluripotent stem cells

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Trisomy 21-associated defects ...... induced pluripotent stem cells

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Trisomy 21-associated defects ...... induced pluripotent stem cells

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Proceedings of the National Academy of Sciences of the United States of America

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Trisomy 21-associated defects ...... induced pluripotent stem cells

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Daniel Vandorn

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Deborah L French

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Jason A Mills

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Joanna B Opalinska

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Joanna M Tober

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John Kim Choi

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Marta Byrska-Bishop

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Nancy A Speck

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Paul Gadue

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Stella T Chou

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Bioconductor: open software development for computational biology and bioinformatics

A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors

Summaries of Affymetrix GeneChip probe level data

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

Chromosome 21 and down syndrome: from genomics to pathophysiology

A TALE nuclease architecture for efficient genome editing

To err (meiotically) is human: the genesis of human aneuploidy

Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

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17573-17578

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10.1073/PNAS.1211175109

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43

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109

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Mitchell J Weiss

Robert J. Nemiroff

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2012-10-08T00:00:00Z

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232075324

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23045704

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Human Induced Pluripotent Stem Cells

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3491490

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