Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis.
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The molecular basis of hypertrophic scarsMesothelial cells in tissue repair and fibrosisBlockade of IL-6 Trans signaling attenuates pulmonary fibrosisFibroblast growth factor 2 is required for epithelial recovery, but not for pulmonary fibrosis, in response to bleomycinSTAT-3 contributes to pulmonary fibrosis through epithelial injury and fibroblast-myofibroblast differentiation.Interleukin-6 cytokine: a multifunctional glycoprotein for cancer.The enigmatic cytokine oncostatin m and roles in diseaseThe fibrogenic actions of lung fibroblast-derived urokinase: a potential drug target in IPF.Interleukin-6 (IL-6) trans signaling drives a STAT3-dependent pathway that leads to hyperactive transforming growth factor-β (TGF-β) signaling promoting SMAD3 activation and fibrosis via Gremlin protein.Heterogeneity in fibroblast proliferation and survival in idiopathic pulmonary fibrosis.Interleukin-6 in renal disease and therapy.Interleukin-6: a new therapeutic target in systemic sclerosis?WISP1 mediates IL-6-dependent proliferation in primary human lung fibroblasts.Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice.Idiopathic pulmonary fibrosis and a role for autoimmunity.Regulation of IL-33 by Oncostatin M in Mouse Lung Epithelial Cells.Bidirectional role of IL-6 signal in pathogenesis of lung fibrosis.Epigenetic factors as drivers of fibrosis in systemic sclerosis.Mucosal production of uric acid by airway epithelial cells contributes to particulate matter-induced allergic sensitization.Overexpression of OSM and IL-6 impacts the polarization of pro-fibrotic macrophages and the development of bleomycin-induced lung fibrosis.WNT/β-catenin signaling induces IL-1β expression by alveolar epithelial cells in pulmonary fibrosis.Niclosamide Prevents Systemic Sclerosis in a Reactive Oxygen Species-Induced Mouse Model.Oncostatin M modulates fibroblast function via signal transducers and activators of transcription proteins-3.STAT3 controls COL1A2 enhancer activation cooperatively with JunB, regulates type I collagen synthesis posttranscriptionally, and is essential for lung myofibroblast differentiation.Beneficial effects of bile acid receptor agonists in pulmonary disease models.Smad3-STAT3 crosstalk in pathophysiological contexts.IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 signaling pathway.Innate immune signaling and stem cell renewal in idiopathic pulmonary fibrosis.RNAi screening identifies a mechanosensitive ROCK-JAK2-STAT3 network central to myofibroblast activation.Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis.Delayed Administration of WP1066, an STAT3 Inhibitor, Ameliorates Radiation-Induced Lung Injury in Mice.Oncostatin M overexpression induces matrix deposition, STAT3 activation, and SMAD1 Dysregulation in lungs of fibrosis-resistant BALB/c mice.Tumor necrosis factor-costimulated T lymphocytes from patients with systemic sclerosis trigger collagen production in fibroblasts.MicroRNA-708-3p as a potential therapeutic target via the ADAM17-GATA/STAT3 axis in idiopathic pulmonary fibrosis.
P2860
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P2860
Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Genetic partitioning of interl ...... Smad3-mediated lung fibrosis.
@ast
Genetic partitioning of interl ...... Smad3-mediated lung fibrosis.
@en
type
label
Genetic partitioning of interl ...... Smad3-mediated lung fibrosis.
@ast
Genetic partitioning of interl ...... Smad3-mediated lung fibrosis.
@en
prefLabel
Genetic partitioning of interl ...... Smad3-mediated lung fibrosis.
@ast
Genetic partitioning of interl ...... Smad3-mediated lung fibrosis.
@en
P2093
P2860
P50
P356
P1476
Genetic partitioning of interl ...... Smad3-mediated lung fibrosis.
@en
P2093
Andrew G Jarnicki
Brent S McKenzie
Cecilia M Prêle
Darryl A Knight
Gary P Anderson
Geoffrey J Laurent
Hong Jian Zhu
Hui Ling Lau
Jessica Jones
P2860
P304
P356
10.1002/EMMM.201100604
P577
2012-06-08T00:00:00Z