Oligomerization-dependent regulation of motility and morphogenesis by the collagen XVIII NC1/endostatin domain
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Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrinsFlexible heteroarotinoid (Flex-Het) SHetA2 inhibits angiogenesis in vitro and in vivoDecoding the Matrix: Instructive Roles of Proteoglycan ReceptorsCrystal Structure of Human Collagen XVIII Trimerization Domain: A Novel Collagen Trimerization FoldHuman alpha1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by alpha1beta1 integrin.A novel cell binding site in the coiled-coil domain of laminin involved in capillary morphogenesis.Antiangiogenic and antitumor effects of Trypanosoma cruzi Calreticulin.Mutations in Lama1 disrupt retinal vascular development and inner limiting membrane formation.Cell proliferation and migration are modulated by Cdk-1-phosphorylated endothelial-monocyte activating polypeptide IIThe many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis.New insights into the role of extracellular matrix during tumor onset and progression.New functional roles for non-collagenous domains of basement membrane collagensCellular actions and signaling by endostatin.Extension of the in vivo half-life of endostatin and its improved anti-tumor activities upon fusion to a humanized antibody against tumor-associated glycoprotein 72 in a mouse model of human colorectal carcinoma.IBC's 22nd Annual Antibody Engineering and 9th Annual Antibody Therapeutics International Conferences and the 2011 Annual Meeting of The Antibody Society, December 5-8, 2011, San Diego, CA.Diverse biological functions of extracellular collagen processing enzymesAngiogenic inhibitors: a new therapeutic strategy in oncology.The NC1/endostatin domain of Caenorhabditis elegans type XVIII collagen affects cell migration and axon guidance.A novel peptide from human apolipoprotein(a) inhibits angiogenesis and tumor growth by targeting c-Src phosphorylation in VEGF-induced human umbilical endothelial cells.FAK and p38-MAP kinase-dependent activation of apoptosis and caspase-3 in retinal endothelial cells by alpha1(IV)NC1Matricryptins and matrikines: biologically active fragments of the extracellular matrix.Endostatin overexpression specifically in the lens and skin leads to cataract and ultrastructural alterations in basement membranes.VEGF receptors on PC12 cells mediate transient activation of ERK1/2 and Akt: comparison of nerve growth factor and vascular endothelial growth factor.The morphogenic properties of oligomeric endostatin are dependent on cell surface heparan sulfate.Endostatin inhibits human tongue carcinoma cell invasion and intravasation and blocks the activation of matrix metalloprotease-2, -9, and -13.Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cellsAttenuation of ultraviolet A-induced alterations in NIH3T3 dermal fibroblasts by melatonin.Endostatin binds nerve growth factor and thereby inhibits neurite outgrowth and neuronal migration in-vitro.Epithelial-mesenchymal interactions are linked to neovascularization.Intra-arterial delivery of endostatin gene to brain tumors prolongs survival and alters tumor vessel ultrastructure.Gene therapy for antiangiogenesis.Endostatin expression in the murine model of ischaemia/reperfusion-induced acute renal failure.
P2860
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P2860
Oligomerization-dependent regulation of motility and morphogenesis by the collagen XVIII NC1/endostatin domain
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Oligomerization-dependent regu ...... en XVIII NC1/endostatin domain
@ast
Oligomerization-dependent regu ...... en XVIII NC1/endostatin domain
@en
type
label
Oligomerization-dependent regu ...... en XVIII NC1/endostatin domain
@ast
Oligomerization-dependent regu ...... en XVIII NC1/endostatin domain
@en
prefLabel
Oligomerization-dependent regu ...... en XVIII NC1/endostatin domain
@ast
Oligomerization-dependent regu ...... en XVIII NC1/endostatin domain
@en
P2093
P2860
P356
P1476
Oligomerization-dependent regu ...... en XVIII NC1/endostatin domain
@en
P2093
B D Ackley
G Garcia-Cardeña
J Kamihara
K Javaherian
K R LaMontagne
R C Mulligan
P2860
P304
P356
10.1083/JCB.152.6.1233
P407
P577
2001-03-01T00:00:00Z