Structure-based Discovery of Novel Small Molecule Wnt Signaling Inhibitors by Targeting the Cysteine-rich Domain of Frizzled.
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Multifunctional DDX3: dual roles in various cancer development and its related signaling pathwaysWnt Drug Discovery: Weaving Through the Screens, Patents and Clinical TrialsDocking Screens for Novel Ligands Conferring New Biology.Apigenin-induced lysosomal degradation of β-catenin in Wnt/β-catenin signaling.Modulating the wnt signaling pathway with small molecules.Small-molecule inhibition of Wnt signaling abrogates dexamethasone-induced phenotype of primary human trabecular meshwork cells.Discovery of novel frizzled-7 inhibitors by targeting the receptor's transmembrane domain.Deregulation of Frizzled Receptors in Hepatocellular Carcinoma.Frizzled-8 integrates Wnt-11 and transforming growth factor-β signaling in prostate cancer.R-spodin2 enhances canonical Wnt signaling to maintain the stemness of glioblastoma cells
P2860
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P2860
Structure-based Discovery of Novel Small Molecule Wnt Signaling Inhibitors by Targeting the Cysteine-rich Domain of Frizzled.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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name
Structure-based Discovery of N ...... teine-rich Domain of Frizzled.
@ast
Structure-based Discovery of N ...... teine-rich Domain of Frizzled.
@en
type
label
Structure-based Discovery of N ...... teine-rich Domain of Frizzled.
@ast
Structure-based Discovery of N ...... teine-rich Domain of Frizzled.
@en
prefLabel
Structure-based Discovery of N ...... teine-rich Domain of Frizzled.
@ast
Structure-based Discovery of N ...... teine-rich Domain of Frizzled.
@en
P2093
P2860
P356
P1476
Structure-based Discovery of N ...... teine-rich Domain of Frizzled.
@en
P2093
Ami Miller
Cristina Guibao
Dianqing Wu
Yiressy C Baday
P2860
P304
30596-30606
P356
10.1074/JBC.M115.673202
P407
P577
2015-10-26T00:00:00Z