Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility: functional competition of collapsin-1 and vascular endothelial growth factor-165.
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The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A-1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein-like protein (EVL) via a novel carboxyl-terminal zyxin-like domainThe endocrine-gland-derived VEGF homologue Bv8 promotes angiogenesis in the testis: Localization of Bv8 receptors to endothelial cellsSemaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1Semaphorin 5A promotes angiogenesis by increasing endothelial cell proliferation, migration, and decreasing apoptosisSelective induction of neuropilin-1 by vascular endothelial growth factor (VEGF): a mechanism contributing to VEGF-induced angiogenesis.The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARGSelective suppression of in vivo tumorigenicity by semaphorin SEMA3F in lung cancer cellsSemaphorin SEMA3F and VEGF have opposing effects on cell attachment and spreadingInhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3BSemaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype.Semaphorin 3B (SEMA3B) induces apoptosis in lung and breast cancer, whereas VEGF165 antagonizes this effectGuidance molecules in lung cancerDual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2Selective requirements for NRP1 ligands during neurovascular patterningIdentification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activityThe semaphorin receptor plexin-B1 specifically interacts with active Rac in a ligand-dependent mannerSemaphorin SEMA3F localization in malignant human lung and cell lines: A suggested role in cell adhesion and cell migrationVascular endothelial growth factor A: just one of multiple mechanisms for sex-specific vascular development within the testis?Control of cellular motility by neuropilin-mediated physical interactionsSemaphorin 3A suppresses tumor growth and metastasis in mice melanoma modelNeuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells.Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF bindingA perspective on the role of class III semaphorin signaling in central nervous system traumaRestricted innervation of uterus and placenta during pregnancy: evidence for a role of the repelling signal Semaphorin 3ANeuropilin-1 is required for endothelial tip cell guidance in the developing central nervous systemSoluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survivalMolecular basis of semaphorin-mediated axon guidanceABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells.Hypoxia induces dilated cardiomyopathy in the chick embryo: mechanism, intervention, and long-term consequencesExpression profiling identifies new function of collapsin response mediator protein 4 as a metastasis-suppressor in prostate cancer.VEGF-A and Semaphorin3A: modulators of vascular sympathetic innervation.Expression of semaphorin 6D in gastric carcinoma and its significanceVascular endothelial growth factor receptor-1 and neuropilin-2 form complexes.Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesisA mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progressionCollapsin response mediator protein-1 and the invasion and metastasis of cancer cells.Decreased expression of SEMA3A is associated with poor prognosis in gastric carcinoma.Expression of VEGF, semaphorin SEMA3F, and their common receptors neuropilins NP1 and NP2 in preinvasive bronchial lesions, lung tumours, and cell lines.Diverse functions for the semaphorin receptor PlexinD1 in development and disease.Decreased semaphorin3A expression correlates with disease activity and histological features of rheumatoid arthritis.
P2860
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P2860
Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility: functional competition of collapsin-1 and vascular endothelial growth factor-165.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Neuropilin-1 mediates collapsi ...... endothelial growth factor-165.
@ast
Neuropilin-1 mediates collapsi ...... endothelial growth factor-165.
@en
type
label
Neuropilin-1 mediates collapsi ...... endothelial growth factor-165.
@ast
Neuropilin-1 mediates collapsi ...... endothelial growth factor-165.
@en
prefLabel
Neuropilin-1 mediates collapsi ...... endothelial growth factor-165.
@ast
Neuropilin-1 mediates collapsi ...... endothelial growth factor-165.
@en
P2093
P2860
P356
P1476
Neuropilin-1 mediates collapsi ...... endothelial growth factor-165.
@en
P2093
P2860
P304
P356
10.1083/JCB.146.1.233
P407
P577
1999-07-01T00:00:00Z