Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
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A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondriaMitochondria-associated ER membranes and Alzheimer diseaseIntracellular Calcium Dysregulation: Implications for Alzheimer's DiseaseEndoplasmic Reticulum Stress and Associated ROSThere's Something Wrong with my MAM; the ER-Mitochondria Axis and Neurodegenerative DiseasesMitochondria-associated membranes as hubs for neurodegenerationNovel subcellular localization for α-synuclein: possible functional consequencesMitochondrial form and functionMitochondrial dysfunction: different routes to Alzheimer's disease therapyMitochondrial genome changes and neurodegenerative diseasesLysosome and calcium dysregulation in Alzheimer's disease: partners in crimeACAT1/SOAT1 as a therapeutic target for Alzheimer's diseasePotential Molecular Mechanisms on the Role of the Sigma-1 Receptor in the Action of Cocaine and MethamphetamineMitochondrial lipids in neurodegenerationExtended ultrastructural characterization of chordoma cells: the link to new therapeutic optionsEnteroviruses harness the cellular endocytic machinery to remodel the host cell cholesterol landscape for effective viral replication.Oxidative stress and mitochondrial dysfunction in Alzheimer's disease.Cross-talk of membrane lipids and Alzheimer-related proteins.Mitochondrial DNA damage in a mouse model of Alzheimer's disease decreases amyloid beta plaque formationOxidative stress and mitochondrial dysfunction across broad-ranging pathologies: toward mitochondria-targeted clinical strategies.Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology.Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol traffickingIs Alzheimer's disease a systemic disease?Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearanceRoles of mitochondrial ubiquitin ligase MITOL/MARCH5 in mitochondrial dynamics and diseases.Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity.Mitofusin-2 knockdown increases ER-mitochondria contact and decreases amyloid β-peptide productionOCIAD2 activates γ-secretase to enhance amyloid β production by interacting with nicastrin.The role of mitochondrial DNA mutation on neurodegenerative diseases.Shaping the dynamic mitochondrial networkIdentification of tetrahydrocarbazoles as novel multifactorial drug candidates for treatment of Alzheimer's disease.Amyloid-β precursor protein: Multiple fragments, numerous transport routes and mechanismsAcyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage.Implications of mitochondrial dynamics on neurodegeneration and on hypothalamic dysfunction.Endoplasmic Reticulum Stress and Autophagy in Homocystinuria Patients with Remethylation Defects.ATP-binding cassette transporters and sterol O-acyltransferases interact at membrane microdomains to modulate sterol uptake and esterificationHuman Mitochondrial DNA-Protein Complexes Attach to a Cholesterol-Rich Membrane StructureA γ-Secretase Independent Role for Presenilin in Calcium Homeostasis Impacts Mitochondrial Function and Morphology in Caenorhabditis elegans.Alzheimer's disease-causing proline substitutions lead to presenilin 1 aggregation and malfunction.Mitochondrion to endoplasmic reticulum apposition length in zebrafish embryo spinal progenitors is unchanged in response to perturbations associated with Alzheimer's disease
P2860
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P2860
Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
@ast
Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
@en
type
label
Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
@ast
Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
@en
prefLabel
Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
@ast
Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
@en
P2093
P2860
P50
P356
P1433
P1476
Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
@en
P2093
Ad J C de Groof
Eric A Schon
Estela Area-Gomez
Marc D Tambini
Maria Del Carmen Lara Castillo
Masato Umeda
Stephen L Sturley
Thomas D Bird
P2860
P304
P356
10.1038/EMBOJ.2012.202
P407
P577
2012-08-14T00:00:00Z