Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment - Wikidata - awgldk - TriplyDB

Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment

Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment

http://www.wikidata.org/entity/Q36385159

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CD44 in rheumatoid arthritis Leukocyte integrins: role in leukocyte recruitment and as therapeutic targets in inflammatory disease Hyaluronan synthesis is necessary for autoreactive T-cell trafficking, activation, and Th1 polarization Natalizumab and the role of alpha 4-integrin antagonism in the treatment of multiple sclerosis The adhesion receptor CD44 promotes atherosclerosis by mediating inflammatory cell recruitment and vascular cell activation CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis CD44-specific antibody treatment and CD44 deficiency exert distinct effects on leukocyte recruitment in experimental arthritis.Development of a peptide inhibitor of hyaluronan-mediated leukocyte trafficking.PDE8 regulates rapid Teff cell adhesion and proliferation independent of ICER.Negative regulation of epithelium-neutrophil interactions via activation of CD44.CD44 antibodies and immune thrombocytopenia in the amelioration of murine inflammatory arthritis.RHAMM, a receptor for hyaluronan-mediated motility, compensates for CD44 in inflamed CD44-knockout mice: a different interpretation of redundancy.Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity.Short day lengths augment stress-induced leukocyte trafficking and stress-induced enhancement of skin immune function.Inhibition of hyaluronan synthesis protects against central nervous system (CNS) autoimmunity and increases CXCL12 expression in the inflamed CNS.The CD44-initiated pathway of T-cell extravasation uses VLA-4 but not LFA-1 for firm adhesion.Comparative study on the therapeutic potential of neurally differentiated stem cells in a mouse model of multiple sclerosis.Overexpression of CD44 in neural precursor cells improves trans-endothelial migration and facilitates their invasion of perivascular tissues in vivo.A mutation in a CD44 variant of inflammatory cells enhances the mitogenic interaction of FGF with its receptor.Therapy with recombinant T-cell receptor ligand reduces infarct size and infiltrating inflammatory cells in brain after middle cerebral artery occlusion in mice Early treatment with anti-VLA-4 mAb can prevent the infiltration and/or development of pathogenic CD11b+CD4+ T cells in the CNS during progressive EAE.4-methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancer.CD44 mobilization in allogeneic dendritic cell-T cell immunological synapse plays a key role in T cell activation Anti-CD44 antibody treatment lowers hyperglycemia and improves insulin resistance, adipose inflammation, and hepatic steatosis in diet-induced obese mice.beta2-integrins in demyelinating disease: not adhering to the paradigm.Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS).Cell therapy for multiple sclerosis.Immunosuppressive potential of human amnion epithelial cells in the treatment of experimental autoimmune encephalomyelitis Expression of interleukin-15 in mouse and human atherosclerotic lesions.Suppressor activity and potency among regulatory T cells is discriminated by functionally active CD44 p150/95 (CD11c/CD18) expression is required for the development of experimental autoimmune encephalomyelitis.The effect of anti-CD44 monoclonal antibodies on differentiation and proliferation of human acute myeloid leukemia cells.Co-transplantation of pure blood stem cells with antigen-specific but not bulk T cells augments functional immunity Expression-based genome-wide association study links the receptor CD44 in adipose tissue with type 2 diabetes.Pineal-dependent and -independent effects of photoperiod on immune function in Siberian hamsters (Phodopus sungorus).Discordant effects of anti-VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis.Platelets contribute to the pathogenesis of experimental autoimmune encephalomyelitis.Blocking adhesion molecules as therapy for multiple sclerosis: natalizumab.Phenotype of Antigen Unexperienced TH Cells in the Inflamed Central Nervous System in Experimental Autoimmune Encephalomyelitis.Suppression of experimental autoimmune encephalomyelitis by extracellular adherence protein of Staphylococcus aureus.

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P2860

Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment

http://www.wikidata.org/entity/Q36385159

description

1999 nî lūn-bûn

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1999年の論文

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年學術文章

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1999年學術文章

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1999年學術文章

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name

Antibodies to CD44 and integri ...... econdary leukocyte recruitment

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Antibodies to CD44 and integri ...... econdary leukocyte recruitment

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type

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Antibodies to CD44 and integri ...... econdary leukocyte recruitment

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Antibodies to CD44 and integri ...... econdary leukocyte recruitment

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prefLabel

Antibodies to CD44 and integri ...... econdary leukocyte recruitment

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Antibodies to CD44 and integri ...... econdary leukocyte recruitment

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Proceedings of the National Academy of Sciences of the United States of America

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Antibodies to CD44 and integri ...... econdary leukocyte recruitment

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C Piercy

http://www.w3.org/2001/XMLSchema#string

I L Weissman

http://www.w3.org/2001/XMLSchema#string

L Steinman

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S Brocke

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T Veromaa

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P2860

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

Adhesion receptors of the immune system

Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity

Lymphocyte homing and homeostasis

Expression of the human leukocyte adhesion molecule, LAM1. Identity with the TQ1 and Leu-8 differentiation antigens.

A cell-surface molecule involved in organ-specific homing of lymphocytes.

Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system.

Proinflammatory stimuli regulate endothelial hyaluronan expression and CD44/HA-dependent primary adhesion

Myelin specific, autoaggressive T cell clones in the normal immune repertoire: their nature and their regulation.

T cells in the lesion of experimental autoimmune encephalomyelitis. Enrichment for reactivities to myelin basic protein and to heat shock proteins.

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6896-6901

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12

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10359810

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22013

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