The Roles of MDM2 and MDMX Phosphorylation in Stress Signaling to p53.
about
The cis conformation of proline leads to weaker binding of a p53 peptide to MDM2 compared to trans.Stress-induced alternative splice forms of MDM2 and MDMX modulate the p53-pathway in distinct waysGenetic Variations in the TP53 Pathway in Native Americans Strongly Suggest Adaptation to the High Altitudes of the Andes.AXL receptor signalling suppresses p53 in melanoma through stabilization of the MDMX-MDM2 complex.The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression.E3 ubiquitin ligase TRIM32 negatively regulates tumor suppressor p53 to promote tumorigenesis.Cisplatin causes cell death via TAB1 regulation of p53/MDM2/MDMX circuitry.The fate of murine double minute X (MdmX) is dictated by distinct signaling pathways through murine double minute 2 (Mdm2).Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist.Role of the N-terminal lid in regulating the interaction of phosphorylated MDMX with p53.Inhibition of Mdmx (Mdm4) in vivo induces anti-obesity effects.Peli1 modulates the subcellular localization and activity of Mdmx.MDMX under stress: the MDMX-MDM2 complex as stress signals hub
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P2860
The Roles of MDM2 and MDMX Phosphorylation in Stress Signaling to p53.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
The Roles of MDM2 and MDMX Phosphorylation in Stress Signaling to p53.
@ast
The Roles of MDM2 and MDMX Phosphorylation in Stress Signaling to p53.
@en
type
label
The Roles of MDM2 and MDMX Phosphorylation in Stress Signaling to p53.
@ast
The Roles of MDM2 and MDMX Phosphorylation in Stress Signaling to p53.
@en
prefLabel
The Roles of MDM2 and MDMX Phosphorylation in Stress Signaling to p53.
@ast
The Roles of MDM2 and MDMX Phosphorylation in Stress Signaling to p53.
@en
P2860
P356
P1433
P1476
The Roles of MDM2 and MDMX Phosphorylation in Stress Signaling to p53.
@en
P2093
Jiandong Chen
P2860
P304
P356
10.1177/1947601912454733
P577
2012-03-01T00:00:00Z