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A gammaherpesvirus Bcl-2 ortholog blocks B cell receptor-mediated apoptosis and promotes the survival of developing B cells in vivoPatterns of receptor revision in the immunoglobulin heavy chains of a teleost fishInterferon regulatory factor 4 and 8 in B-cell development.SLAP deficiency decreases dsDNA autoantibody productionActivation of Ras overcomes B-cell tolerance to promote differentiation of autoreactive B cells and production of autoantibodiesS1P3 confers differential S1P-induced migration by autoreactive and non-autoreactive immature B cells and is required for normal B-cell development.The ataxia telangiectasia mutated and cyclin D3 proteins cooperate to help enforce TCRβ and IgH allelic exclusionBAFF receptor signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signalingThe development of mature B lymphocytes requires the combined function of CD19 and the p110δ subunit of PI3KPositive selection of natural poly-reactive B cells in the periphery occurs independent of heavy chain allelic inclusionMurine gammaherpesvirus 68 infection protects lupus-prone mice from the development of autoimmunity.Dual-reactive B cells are autoreactive and highly enriched in the plasmablast and memory B cell subsets of autoimmune mice.Receptor editing and genetic variability in human autoreactive B cells.A role for interferon regulatory factor 4 in receptor editing.Central and peripheral RAG protein re-expression: underestimate mechanisms of tolerance?Regulation of the T cell response.Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors.Autoimmunity risk alleles: hotspots in B cell regulatory signaling pathways.Antigen and cytokine receptor signals guide the development of the naïve mature B cell repertoire.Tolerance checkpoints in B-cell development: Johnny B good.TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice.The antibody response to an HLA mismatch: a model for nonself-self discrimination in relation to HLA epitope immunogenicity.The role of B lymphocyte stimulator in B cell biology: implications for the treatment of lupus.Adhesion receptors involved in HSC and early-B cell interactions with bone marrow microenvironment.Breaching peripheral tolerance promotes the production of HIV-1-neutralizing antibodies.Negative selection of self-reactive chicken B cells requires B cell receptor signaling and is independent of the bursal microenvironment.Immunological tolerance as a barrier to protective HIV humoral immunity.Central tolerance regulates B cells reactive with Goodpasture antigen alpha3(IV)NC1 collagen.Phenotyping of autoreactive B cells with labeled nucleosomes in 56R transgenic mice.Activation of the MEK-ERK Pathway Is Necessary but Not Sufficient for Breaking Central B Cell Tolerance.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Receptor editing for better or for worse.
@ast
Receptor editing for better or for worse.
@en
type
label
Receptor editing for better or for worse.
@ast
Receptor editing for better or for worse.
@en
prefLabel
Receptor editing for better or for worse.
@ast
Receptor editing for better or for worse.
@en
P921
P1476
Receptor editing for better or for worse.
@en
P2093
Raul M Torres
Roberta Pelanda
P304
P356
10.1016/J.COI.2006.01.005
P577
2006-02-03T00:00:00Z