Blockade of tumor growth due to matrix metalloproteinase-9 inhibition is mediated by sequential activation of beta1-integrin, ERK, and NF-kappaB. - Wikidata - awgldk - TriplyDB

Blockade of tumor growth due to matrix metalloproteinase-9 inhibition is mediated by sequential activation of beta1-integrin, ERK, and NF-kappaB.

Blockade of tumor growth due to matrix metalloproteinase-9 inhibition is mediated by sequential activation of beta1-integrin, ERK, and NF-kappaB.

http://www.wikidata.org/entity/Q36392027

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Gelatinase B/MMP-9 in Tumour Pathogenesis and Progression SPARC mediates Src-induced disruption of actin cytoskeleton via inactivation of small GTPases Rho-Rac-Cdc42 FXR promotes endothelial cell motility through coordinated regulation of FAK and MMP-9.Astragalus saponins downregulate vascular endothelial growth factor under cobalt chloride-stimulated hypoxia in colon cancer cells.The role of MMP-9 in the anti-angiogenic effect of secreted protein acidic and rich in cysteine.Targeting MMP-9, uPAR, and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells.Urokinase plasminogen activator receptor and/or matrix metalloproteinase-9 inhibition induces apoptosis signaling through lipid rafts in glioblastoma xenograft cells SPARC overexpression inhibits cell proliferation in neuroblastoma and is partly mediated by tumor suppressor protein PTEN and AKT.Pancreatic cancer-specific cell death induced in vivo by cytoplasmic-delivered polyinosine-polycytidylic acid.siRNA-mediated downregulation of MMP-9 and uPAR in combination with radiation induces G2/M cell-cycle arrest in Medulloblastoma.Cathepsin B facilitates autophagy-mediated apoptosis in SPARC overexpressed primitive neuroectodermal tumor cells.MMP-2 mediates mesenchymal stem cell tropism towards medulloblastoma tumors SPARC stimulates neuronal differentiation of medulloblastoma cells via the Notch1/STAT3 pathway.MMP-9 silencing regulates hTERT expression via β1 integrin-mediated FAK signaling and induces senescence in glioma xenograft cells.Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-κB network Identification of a novel pro-apopotic function of NF-kappaB in the DNA damage response.Piceatannol inhibits MMP-9-dependent invasion of tumor necrosis factor-α-stimulated DU145 cells by suppressing the Akt-mediated nuclear factor-κB pathway.Notch signaling regulates tumor-induced angiogenesis in SPARC-overexpressed neuroblastoma The secreted protein acidic and rich in cysteine (SPARC) induces endoplasmic reticulum stress leading to autophagy-mediated apoptosis in neuroblastoma.Anti-matrix metalloproteinase-9 DNAzyme decreases tumor growth in the MMTV-PyMT mouse model of breast cancer.Conus vexillum venom induces oxidative stress in Ehrlich's ascites carcinoma cells: an insight into the mechanism of induction.RNAi-mediated downregulation of radiation-induced MMP-9 leads to apoptosis via activation of ERK and Akt in IOMM-Lee cells.Inhibition of nuclear factor-kappa B enhances the tumor growth of ovarian cancer cell line derived from a low-grade papillary serous carcinoma in p53-independent pathway A novel synthetic derivative of the natural product berbamine inhibits cell viability and induces apoptosis of human osteosarcoma cells, associated with activation of JNK/AP-1 signaling.β1-Integrin via NF-κB signaling is essential for acquisition of invasiveness in a model of radiation treated in situ breast cancer.Bee venom in cancer therapy.Metastasis review: from bench to bedside.Functional expression of calcium-permeable canonical transient receptor potential 4-containing channels promotes migration of medulloblastoma cells.Brain cancer stem cells: current status on glioblastoma multiforme.Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model.Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation.Activity of Eribulin in a Primary Culture of Well-Differentiated/Dedifferentiated Adipocytic Sarcoma.

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P2860

Blockade of tumor growth due to matrix metalloproteinase-9 inhibition is mediated by sequential activation of beta1-integrin, ERK, and NF-kappaB.

http://www.wikidata.org/entity/Q36392027

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2007 nî lūn-bûn

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2007年の論文

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Blockade of tumor growth due t ...... -integrin, ERK, and NF-kappaB.

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Blockade of tumor growth due t ...... -integrin, ERK, and NF-kappaB.

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Blockade of tumor growth due t ...... -integrin, ERK, and NF-kappaB.

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Chandramu Chetty

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Jasti S Rao

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Praveen Bhoopathi

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Sajani S Lakka

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Sateesh Kunigal

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Sravan K Vanamala

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P2860

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

Integrins: versatility, modulation, and signaling in cell adhesion

MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation.

Aberrant rel/nfkb genes and activity in human cancer

Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

New functions for the matrix metalloproteinases in cancer progression

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

How matrix metalloproteinases regulate cell behavior

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