Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice - Wikidata - awgldk - TriplyDB

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

http://www.wikidata.org/entity/Q36392687

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Unraveling insulin-like growth factor binding protein-3 actions in human disease Inactivation of the acid labile subunit gene in mice results in mild retardation of postnatal growth despite profound disruptions in the circulating insulin-like growth factor system Human conditions of insulin-like growth factor-I (IGF-I) deficiency Optimizing IGF-I for skeletal muscle therapeutics Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1 Respiratory manifestations in endocrine diseases Type I insulin-like growth factor as a liver reserve assessment tool in hepatocellular carcinoma Role of IGF-I signaling in muscle bone interactions Regulation of Long Bone Growth in Vertebrates; It Is Time to Catch Up Investigational agents for the treatment of growth hormone-insensitivity syndrome Hepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levels Burn-induced changes in IGF-I and IGF-binding proteins are partially glucocorticoid dependent Differential regulation of Shc adaptor proteins in skeletal muscle, spinal cord and forebrain of aged rats with sensorimotor impairment Insulin-responsive nuclear proteins facilitate Sp1 interactions with the insulin-like growth factor-I gene Mex3c regulates insulin-like growth factor 1 (IGF1) expression and promotes postnatal growth Liver-derived IGF-I regulates mean life span in mice Muscle mechano growth factor is preferentially induced by growth hormone in growth hormone-deficient lit/lit mice.Acromegaly and serum insulin-like growth factor I.Neurodevelopmental effects of insulin-like growth factor signaling.Pathological impact of SMN2 mis-splicing in adult SMA mice Growth hormone and the heart.The COMT val158met polymorphism is associated with early pubertal development, height and cortical bone mass in girls.Disruption of insulin-like growth factor-I expression in type IIalphaI collagen-expressing cells reduces bone length and width in mice.Characterization of SV-40 Tag rats as a model to study prostate cancer.Effects of taurine supplementation on bone mineral density in ovariectomized rats fed calcium deficient diet.Hormone replacement therapy and physical function in healthy older men. Time to talk hormones?Endogenous IGF-I and alphaVbeta3 integrin ligands regulate increased smooth muscle hyperplasia in stricturing Crohn's disease Deletion of IGF-I receptor (IGF-IR) in primary osteoblasts reduces GH-induced STAT5 signaling.Increase in insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding protein 1 after supplementation with selenium and coenzyme Q10. A prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens.The GH/IGF-1 axis in ageing and longevity Conditional knockout of mouse insulin-like growth factor-1 gene using the Cre/loxP system.Astragalus Extract Mixture HT042 Increases Longitudinal Bone Growth Rate by Upregulating Circulatory IGF-1 in Rats.Expression Profiles of the Insulin-like Growth Factor System Components in Liver Tissue during Embryonic and Postnatal Growth of Erhualian and Yorkshire Reciprocal Cross F1 Pigs.The IGF axis and hepatocarcinogenesis.Targeting insulin-like growth factor axis in hepatocellular carcinoma.Elevated levels of hepatocyte nuclear factor 3beta in mouse hepatocytes influence expression of genes involved in bile acid and glucose homeostasis.Role of IGF-I and the TNFα/NF-κB pathway in the induction of muscle atrogenes by acute inflammation.Abnormal changes in NKT cells, the IGF-1 axis, and liver pathology in an animal model of ALS.Proteoglycan 4: a dynamic regulator of skeletogenesis and parathyroid hormone skeletal anabolism.Growth hormone, IGF-I and insulin and their abuse in sport.

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Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

http://www.wikidata.org/entity/Q36392687

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Proceedings of the National Academy of Sciences of the United States of America

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Liver-derived insulin-like gro ...... postnatal body growth in mice

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D LeRoith

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J L Liu

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J O Jansson

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P2860

Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants

Inducible gene targeting in mice using the Cre/lox system

Insulin-like growth factors and their binding proteins: biological actions

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

Inducible gene targeting in mice

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

Role of insulin-like growth factors in embryonic and postnatal growth

Recombinant human insulin-like growth factor I stimulates growth and has distinct effects on organ size in hypophysectomized rats.

Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action.

Evidence suggesting that the direct growth-promoting effect of growth hormone on cartilage in vivo is mediated by local production of somatomedin.

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