STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity. - Wikidata - awgldk - TriplyDB

STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity.

STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity.

http://www.wikidata.org/entity/Q36394326

about

DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity.The host STING pathway at the interface of cancer and immunity Therapy of solid tumors using probiotic Symbioflor-2: restraints and potential.Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer.Decreased expression of STING predicts poor prognosis in patients with gastric cancer.cGAS is essential for the antitumor effect of immune checkpoint blockade.Promising Targets for Cancer Immunotherapy: TLRs, RLRs, and STING-Mediated Innate Immune Pathways Type I IFN and not TNF, is Essential for Cyclic Di-nucleotide-elicited CTL by a Cytosolic Cross-presentation Pathway.Purification of Cyclic GMP-AMP from Viruses and Measurement of Its Activity in Cell Culture.Induction of tumor regression by intratumoral STING agonists combined with anti-programmed death-L1 blocking antibody in a preclinical squamous cell carcinoma model.Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing.cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signaling.Innate immune mediators in cancer: between defense and resistance.Peptide vaccines in cancer-old concept revisited.Innate immune signaling and regulation in cancer immunotherapy.Rationale for stimulator of interferon genes-targeted cancer immunotherapy.Cytosolic nucleic acid sensors and innate immune regulation.DNA Damage and Repair Biomarkers of Immunotherapy Response.An RNA-Based Fluorescent Biosensor for High-Throughput Analysis of the cGAS-cGAMP-STING Pathway.Signalling strength determines proapoptotic functions of STING.cGAS-STING Activation in the Tumor Microenvironment and Its Role in Cancer Immunity.Immunomodulatory and antitumor effects of type I interferons and their application in cancer therapy.Innate sensing of cancer's non-immunologic hallmarks.A STING Agonist Given with OX40 Receptor and PD-L1 Modulators Primes Immunity and Reduces Tumor Growth in Tolerized Mice.cGAS/STING Pathway in Cancer: Jekyll and Hyde Story of Cancer Immune Response.Recent Successes and Future Directions in Immunotherapy of Cutaneous Melanoma.Emerging trends in the immunotherapy of pancreatic cancer.Established T Cell-Inflamed Tumors Rejected after Adaptive Resistance Was Reversed by Combination STING Activation and PD-1 Pathway Blockade.Cytosolic sensing of immuno-stimulatory DNA, the enemy within.Effects of STING stimulation on macrophages: STING agonists polarize into "classically" or "alternatively" activated macrophages?Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site.Modulating Tumor Immunology by Inhibiting Indoleamine 2,3-Dioxygenase (IDO): Recent Developments and First Clinical Experiences.DNA-Containing Exosomes Derived from Cancer Cells Treated with Topotecan Activate a STING-Dependent Pathway and Reinforce Antitumor Immunity.Effective Combination of Innate and Adaptive Immunotherapeutic Approaches in a Mouse Melanoma Model.Silencing of suppressor of cytokine signaling 1 enhances the immunological effect of mucin 1-calreticulin-primed 4T1 cell-treated dendritic cells in breast cancer treatment.Tumor Immuno-Environment in Cancer Progression and Therapy.Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production.Assessing the cGAS-cGAMP-STING Activity of Cancer Cells.Targeting Cytosolic Nucleic Acid-Sensing Pathways for Cancer Immunotherapies.TANK-Binding Kinase 1-Dependent Responses in Health and Autoimmunity.

P2860

Q33804663-4B8B3177-F823-476B-B54A-A563E48CDB9B Q37042237-15E06188-CA9C-41A1-B921-D63268724C0D Q37225613-5FD9AF7F-64E6-4DFD-8031-5D37AAA63184 Q37252611-911425BD-4B71-435A-A37F-2ECE808E2717 Q37630679-25AE74ED-D344-4C9F-8479-2C6DF0D267F8 Q37658955-B3395043-42EC-45E3-86AF-3D735D769E26 Q37690959-F85CB3B6-CC58-4660-9295-115DC7B5D9D5 Q38654647-69AB178A-C1F7-4473-B0B3-0B50085E0737 Q38694896-018F316D-BD21-4D97-AC94-541973CAD0AC Q38711286-8ED355BD-FA4B-4D61-A2BE-848F87FB24C3 Q38959510-6CC93544-4958-4832-A01E-5069D2ACDB2D Q38972881-9636E847-FE31-4EE9-9B71-793ECFADFD94 Q38991015-8A3A88FE-27A5-4524-A2EE-C34F5247FC2E Q39035351-9431F288-3365-44D3-8161-73316B92C8D0 Q39041026-A726189F-2256-4B2A-B479-0813D8930F4B Q39144454-9B8C45FD-A979-4EAA-8B5C-CCF213993A78 Q39195781-7640D094-4A18-4938-BC9A-C05A77D970BE Q39384263-9B7288A3-3091-4CE1-BBB5-2E5727961B5D Q40434927-4D6A8116-72D0-430A-A41E-EE7F23393827 Q41621190-40CA516C-0328-4624-8651-26CF224A2EFF Q41997059-06002DFB-6426-4D9E-998B-96CE58EEC0A2 Q42378527-DED941EE-ACA7-4D4A-AD5F-86845634C499 Q46065433-21F431F3-175B-4159-9E16-C4197DDC8715 Q46094829-2AE18DD3-5EF9-45CF-BBC2-2BD281EE8AB7 Q47132136-07A9D93D-C6D9-4A8E-A043-1840E45AFF1D Q47134263-52442787-F326-45CC-B99E-5DCD6B684C3C Q47248817-95F67076-143E-412B-BFCF-A70AF0AC4B65 Q47391699-8A350929-CA10-4D4C-8580-C364E4AFB43C Q47564798-11FB6D18-5DB6-4816-853D-DF66257FA78B Q47879678-C97810F5-2FAD-4298-98C8-AAB040444925 Q47963534-459E688A-A763-4B12-91AF-BF5DF42E08C9 Q48306002-351093F6-BAFA-4F9E-8B2B-1EC5A6F72A95 Q48370424-192BFC1D-C3D0-4D89-98B5-82B4F504D0C9 Q48375822-D9CE7C11-05BB-4AE3-8255-E82EFFFF8AA1 Q49482744-9E674BF3-C0C4-40DE-A943-F7B566A4560A Q49592937-D7991D55-DEF4-4174-A287-CD67F3EF8AE3 Q49723825-9648C941-9DFC-4E3A-AA49-8786F4A87AA2 Q50097567-FB78B497-7898-42FE-BD0E-05E3E49E1AB8 Q52568331-30C9A3E7-6AFB-4355-A389-A8E4B8E9FD81 Q52645929-7F40DA2B-BCBB-40BE-811D-09F3AA04D8C1

P2860

STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity.

http://www.wikidata.org/entity/Q36394326

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年学术文章

@wuu

2015年学术文章

@zh-cn

2015年学术文章

@zh-hans

2015年学术文章

@zh-my

2015年学术文章

@zh-sg

2015年學術文章

@yue

2015年學術文章

@zh

2015年學術文章

@zh-hant

name

STING activation of tumor endo ...... herapeutic antitumor immunity.

@ast

STING activation of tumor endo ...... herapeutic antitumor immunity.

@en

type

label

STING activation of tumor endo ...... herapeutic antitumor immunity.

@ast

STING activation of tumor endo ...... herapeutic antitumor immunity.

@en

prefLabel

STING activation of tumor endo ...... herapeutic antitumor immunity.

@ast

STING activation of tumor endo ...... herapeutic antitumor immunity.

@en

P1433

Q36394326-038ECBA4-37A9-4770-B04F-9356F94CB3BC

P1476

Q36394326-34ADA3D7-B5F9-46EE-B60C-1123B71BBC0A

P2093

Q36394326-1CF80110-DA72-4CA7-929F-CC029C62CB7D

Q36394326-34A66751-3A10-472C-8873-084FBB38483E

Q36394326-3C8070D8-6354-4C39-9402-EA6111D55E02

Q36394326-467FE04C-7F54-4C72-BE30-8DEE6C57625F

Q36394326-667C14F2-8B3C-43F5-B6FB-3BCEBAB9BC8A

Q36394326-6964B611-A784-468B-ACD0-9F504425F0F3

Q36394326-731B03C8-93B6-4782-99C6-589982CFA58F

Q36394326-7F67E18F-0C41-470C-8DE6-1BE4E18E84E9

Q36394326-883A9D54-50BE-49EC-935E-494DF39BC4AC

Q36394326-8AA9234C-78CA-4E1E-AE9B-302828781713

P2860

Q36394326-07BA4AD1-8F3F-4FC0-950A-A4AC4B1DDEB2

Q36394326-0A54D10F-2CD9-4937-BA36-57950EA17BC4

Q36394326-0B594E50-02AC-4955-8872-FF198B46E0AA

Q36394326-0EF4D5BF-DFA1-48A3-A6FE-8DF1BBB23FD7

Q36394326-14D6EF1D-3624-407B-BE28-8A2E152BC80F

Q36394326-18CC673B-7FF3-43D8-9BC5-27985C83DEF9

Q36394326-1C5AB1EA-BCA6-43F0-AD30-0E91F1430014

Q36394326-233CFB99-F808-44AC-933E-10C013123D14

Q36394326-298A20AE-8FF6-40FB-AE55-EB499E10E8CC

Q36394326-2E1ADCB0-B4E1-42CF-BF81-5827EF9CBA2C

P304

Q36394326-C2BDF313-CF47-4BE8-A4CA-3555CAFFF04B

P31

Q36394326-3509B404-458E-414E-95B8-6358294A5C19

P356

Q36394326-FE5033B6-203F-457E-B157-117A2E9E9953

P407

Q36394326-244A2C57-9A1B-4F41-8BF4-20BD8B4BF0C5

P433

Q36394326-22D683D5-C1DC-4B5D-9EE2-036C9D888CB0

P478

Q36394326-AB2A55A9-0A7F-4319-A662-DCB94EEC54F9

P50

Q36394326-67E66892-D515-49A0-8555-409CB5299B3A

P577

Q36394326-8AAB87CE-AFE8-44DD-8AFD-61483E3C2C5E

P698

Q36394326-D59F16CD-1DBD-4A01-B7B5-C02083E9642D

P921

Q36394326-E6FAC548-6774-44CA-9606-2F369EC8B7E1

P932

Q36394326-65A88B5D-E4E5-4780-AAB2-DA503D30AC19

P356

PNAS.1512832112

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

STING activation of tumor endo ...... herapeutic antitumor immunity.

@en

P2093

Daniel E Speiser

http://www.w3.org/2001/XMLSchema#string

Fabio Martinon

http://www.w3.org/2001/XMLSchema#string

Jeremy Di Domizio

http://www.w3.org/2001/XMLSchema#string

Lukas Flatz

http://www.w3.org/2001/XMLSchema#string

Michel Gilliet

http://www.w3.org/2001/XMLSchema#string

Nicolas Gestermann

http://www.w3.org/2001/XMLSchema#string

Olivier Demaria

http://www.w3.org/2001/XMLSchema#string

Olivier Gaide

http://www.w3.org/2001/XMLSchema#string

Olivier Michielin

http://www.w3.org/2001/XMLSchema#string

Patrick Hwu

http://www.w3.org/2001/XMLSchema#string

P2860

IFI16 is an innate immune sensor for intracellular DNA

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

Neutrophils responsive to endogenous IFN-beta regulate tumor angiogenesis and growth in a mouse tumor model

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

Ipilimumab, vemurafenib, dabrafenib, and trametinib: synergistic competitors in the clinical management of BRAF mutant malignant melanoma

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

Nivolumab plus ipilimumab in advanced melanoma.

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells

P304

15408-15413

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1512832112

http://www.w3.org/2001/XMLSchema#string

P407

P433

50

http://www.w3.org/2001/XMLSchema#string

P478

112

http://www.w3.org/2001/XMLSchema#string

P50

Aude De Gassart

P577

2015-11-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

26607445

http://www.w3.org/2001/XMLSchema#string

P921

P932

4687570

http://www.w3.org/2001/XMLSchema#string