Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.
about
Radiotherapy combination opportunities leveraging immunity for the next oncology practicePrinciples of antibody-mediated TNF receptor activationER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosisCellular inhibitor of apoptosis (cIAP)-mediated ubiquitination of phosphofurin acidic cluster sorting protein 2 (PACS-2) negatively regulates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicityCyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth.The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host diseaseTargeting a novel N-terminal epitope of death receptor 5 triggers tumor cell death.NKG2A inhibits invariant NKT cell activation in hepatic injury.Three agonist antibodies in combination with high-dose IL-2 eradicate orthotopic kidney cancer in mice.Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosisDifferential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2.Predominant antitumor effects by fully human anti-TRAIL-receptor 2 (DR5) monoclonal antibodies in human glioma cells in vitro and in vivo.CD1d-based combination therapy eradicates established tumors in mice.CD1d activation and blockade: a new antitumor strategyTRAIL in cancer therapy: present and future challenges.Combination treatment with TRA-8 anti death receptor 5 antibody and CPT-11 induces tumor regression in an orthotopic model of pancreatic cancerTargeted expression of tumor necrosis factor-related apoptosis-inducing ligand TRAIL in skin protects mice against chemical carcinogenesis.Vismodegib suppresses TRAIL-mediated liver injury in a mouse model of nonalcoholic steatohepatitis.Interleukin-2 rescues helpless effector CD8+ T cells by diminishing the susceptibility to TRAIL mediated death.Neoadjuvant immunotherapy with chitosan and interleukin-12 to control breast cancer metastasisThe Biology of TRAIL and the Role of TRAIL-Based Therapeutics in Infectious DiseasesDetection of Anticancer and Apoptotic Effect of the Produced IgYs against the Three Extracellular Domain of Human DR5 Protein.Targeted ovarian cancer treatment: the TRAILs of resistance.TRAIL and its receptors as targets for cancer therapy.Fc receptor targeting in the treatment of allergy, autoimmune diseases and cancer.Induction of proapoptotic antibodies to triple-negative breast cancer by vaccination with TRAIL death receptor DR5 DNA.Apoptotic and antitumor activity of death receptor antibodies require inhibitory Fcγ receptor engagementRecent developments in cancer chemotherapy oriented towards new targets.TNF-related apoptosis-inducing ligand as a therapeutic agent in autoimmunity and cancer.Studying the role of the immune system on the antitumor activity of a Hedgehog inhibitor against murine osteosarcoma.Triptolide enhances the tumoricidal activity of TRAIL against renal cell carcinomaRecent advances in targeting regulators of apoptosis in cancer cells for therapeutic gain.TRAIL receptor-targeted therapeutics: resistance mechanisms and strategies to avoid them.Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease.Combination therapy of established cancer using a histone deacetylase inhibitor and a TRAIL receptor agonist.The SMAC mimetic, LCL-161, reduces survival in aggressive MYC-driven lymphoma while promoting susceptibility to endotoxic shock.Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanomaAntibodies targeted to TRAIL receptor-2 and ErbB-2 synergize in vivo and induce an antitumor immune responseFrom cancer immunosurveillance to cancer immunotherapy.Epigenetic regulation of the TRAIL/Apo2L apoptotic pathway by histone deacetylase inhibitors: an attractive approach to bypass melanoma immunotherapy resistance
P2860
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P2860
Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.
@ast
Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.
@en
type
label
Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.
@ast
Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.
@en
prefLabel
Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.
@ast
Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.
@en
P2093
P2860
P356
P1476
Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.
@en
P2093
Hisaya Akiba
Jane E Tanner
Kazuyoshi Takeda
Ko Okumura
Naoko Seki
Noriko Yamaguchi
Thomas J Sayers
Yoshihiro Hayakawa
Yuko Kojima
P2860
P304
P356
10.1084/JEM.20031457
P407
P577
2004-02-09T00:00:00Z