The envelope glycoprotein ectodomains determine the efficiency of CD4+ T lymphocyte depletion in simian-human immunodeficiency virus-infected macaques.
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HIV-1 induced bystander apoptosisViremic HIV infected individuals with high CD4 T cells and functional envelope proteins show anti-gp41 antibodies with unique specificity and functionDevelopment of a novel rhesus macaque model with an infectious R5 simian-human immunodeficiency virus encoding HIV-1 CRF08_BC env.Mutations in HIV-1 envelope that enhance entry with the macaque CD4 receptor alter antibody recognition by disrupting quaternary interactions within the trimer.Characterization of simian-human immunodeficiency virus envelope glycoprotein epitopes recognized by neutralizing antibodies from infected monkeysImportance of membrane fusion mediated by human immunodeficiency virus envelope glycoproteins for lysis of primary CD4-positive T cells.Induction of antibodies in guinea pigs and rhesus monkeys against the human immunodeficiency virus type 1 envelope: neutralization of nonpathogenic and pathogenic primary isolate simian/human immunodeficiency virus strains.Simian-human immunodeficiency virus containing a human immunodeficiency virus type 1 subtype-E envelope gene: persistent infection, CD4(+) T-cell depletion, and mucosal membrane transmission in macaquesHuman immunodeficiency virus type 1 strains R5 and X4 induce different pathogenic effects in hu-PBL-SCID mice, depending on the state of activation/differentiation of human target cells at the time of primary infection.Determinants of neutralization resistance in the envelope glycoproteins of a simian-human immunodeficiency virus passaged in vivo.Characterization of primary isolate-like variants of simian-human immunodeficiency virusEnvelope glycoprotein determinants of neutralization resistance in a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2) derived by passage in monkeys.Membrane-fusing capacity of the human immunodeficiency virus envelope proteins determines the efficiency of CD+ T-cell depletion in macaques infected by a simian-human immunodeficiency virusAntigenically distinct conformations of CXCR4.Human Mast cell progenitors can be infected by macrophagetropic human immunodeficiency virus type 1 and retain virus with maturation in vitro.HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activationAsn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS.High frequency of virus-specific B lymphocytes in germinal centers of simian-human immunodeficiency virus-infected rhesus monkeysModifications of the human immunodeficiency virus envelope glycoprotein enhance immunogenicity for genetic immunization.Increased mucosal transmission but not enhanced pathogenicity of the CCR5-tropic, simian AIDS-inducing simian/human immunodeficiency virus SHIV(SF162P3) maps to envelope gp120.Human retroviruses after 20 years: a perspective from the past and prospects for their future control.Cytolysis by CCR5-using human immunodeficiency virus type 1 envelope glycoproteins is dependent on membrane fusion and can be inhibited by high levels of CD4 expression.Conformational alterations in the CD4 binding cavity of HIV-1 gp120 influencing gp120-CD4 interactions and fusogenicity of HIV-1 envelopes derived from brain and other tissuesHIV-1 escape from the CCR5 antagonist maraviroc associated with an altered and less-efficient mechanism of gp120-CCR5 engagement that attenuates macrophage tropismViral persistence in vivo through selection of neutralizing antibody-escape variants.HIV ENV glycoprotein-mediated bystander apoptosis depends on expression of the CCR5 co-receptor at the cell surface and ENV fusogenic activityIsolation of CD4-independent primary human immunodeficiency virus type 1 isolates that are syncytium inducing and acutely cytopathic for CD8+ lymphocytes.Targeting HIV-1 gp41-induced fusion and pathogenesis for anti-viral therapyMolecularly cloned SHIV-CN97001: a replication-competent, R5 simian/human immunodeficiency virus containing env of a primary Chinese HIV-1 clade C isolate.Disparate effects of acute and chronic infection with SIVmac239 or SHIV-89.6P on macaque plasmacytoid dendritic cells.Blockade of HIV-1 infection of New World monkey cells occurs primarily at the stage of virus entry.Adaptation of the human immunodeficiency virus type 1 envelope glycoproteins to new world monkey receptors.Viral-mediated fusion of mesenchymal stem cells with cells of the infarcted heart hinders healing via decreased vascularization and immune modulationSingle-cell RNA-seq reveals activation of unique gene groups as a consequence of stem cell-parenchymal cell fusion.Role of HIV Gp41 mediated fusion/hemifusion in bystander apoptosis.Influence of long terminal repeat and env on the virulence phenotype of equine infectious anemia virus.Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120.Infection of rhesus macaques with a pool of simian immunodeficiency virus with the envelope genes from acute HIV-1 infections.Genetic signatures of HIV-1 envelope-mediated bystander apoptosis.The selection of low envelope glycoprotein reactivity to soluble CD4 and cold during simian-human immunodeficiency virus infection of rhesus macaques.
P2860
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P2860
The envelope glycoprotein ectodomains determine the efficiency of CD4+ T lymphocyte depletion in simian-human immunodeficiency virus-infected macaques.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
The envelope glycoprotein ecto ...... iency virus-infected macaques.
@ast
The envelope glycoprotein ecto ...... iency virus-infected macaques.
@en
type
label
The envelope glycoprotein ecto ...... iency virus-infected macaques.
@ast
The envelope glycoprotein ecto ...... iency virus-infected macaques.
@en
prefLabel
The envelope glycoprotein ecto ...... iency virus-infected macaques.
@ast
The envelope glycoprotein ecto ...... iency virus-infected macaques.
@en
P2093
P2860
P356
P1476
The envelope glycoprotein ecto ...... iency virus-infected macaques.
@en
P2093
B Etemad-Moghadam
D Margolin
D Schenten
E Desjardins
G B Karlsson
J Sodroski
K Tenner-Racz
P2860
P304
P356
10.1084/JEM.188.6.1159
P407
P50
P577
1998-09-01T00:00:00Z