Aldehyde dehydrogenase 1A1--a new mediator of resistance to temozolomide in glioblastoma.
about
Side population cells as prototype of chemoresistant, tumor-initiating cellsA conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma CareExpression Profile of Genes Related to Drug Metabolism in Human Brain TumorsEffects of temozolomide (TMZ) on the expression and interaction of heat shock proteins (HSPs) and DNA repair proteins in human malignant glioma cells.Concise review: bullseye: targeting cancer stem cells to improve the treatment of gliomas by repurposing disulfiram.Discovery of Power-Law Growth in the Self-Renewal of Heterogeneous Glioma Stem Cell PopulationsAldehyde dehydrogenase 1A1 circumscribes high invasive glioma cells and predicts poor prognosis.ALDH1A3: A Marker of Mesenchymal Phenotype in Gliomas Associated with Cell InvasionA High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity.Cancer stem cells and chemoresistance: The smartest survives the raidDisulfiram targets cancer stem-like cells and reverses resistance and cross-resistance in acquired paclitaxel-resistant triple-negative breast cancer cells.ALDH1A1 induces resistance to CHOP in diffuse large B-cell lymphoma through activation of the JAK2/STAT3 pathway.YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells.Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage.Pregnane X-receptor promotes stem cell-mediated colon cancer relapseTemozolomide induces autophagy in primary and established glioblastoma cells in an EGFR independent manner.Emerging role of NRF2 in chemoresistance by regulating drug-metabolizing enzymes and efflux transporters.β-escin selectively targets the glioblastoma-initiating cell population and reduces cell viability.Thiophene bridged aldehydes (TBAs) image ALDH activity in cells via modulation of intramolecular charge transfer.Aldehyde dehydrogenase 1 expression has prognostic significance in patients with glioma.Pharmacological targeting of apelin impairs glioblastoma growth.Drug repurposing for the treatment of glioblastoma multiforme.Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro.Proteome Profiling of Primary Pancreatic Ductal Adenocarcinomas Undergoing Additive Chemoradiation Link ALDH1A1 to Early Local Recurrence and Chemoradiation ResistanceDevelopments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma
P2860
Q26823433-CEAA0081-8262-4132-84A7-766844A6303EQ26851160-C5E5C459-8B11-4A8E-80F0-D0F437D149BBQ28551028-D8D13347-EC14-446F-B6B2-91632C8EA72BQ35078800-7469AA43-86BA-476C-8D60-E192B1050E13Q35542866-90518155-B605-4FA4-B5CD-B2B3719BAA01Q35748846-CD8EA45A-DC9A-4D3D-BDD5-A35B38A778B5Q35758016-C4C8B59D-8BFA-4020-A743-320BE9FD0F4DQ35843516-8700F0D1-82C2-4084-944A-D9780A1E9702Q36262477-372279BB-E058-47AE-9C6F-DA80D9DA6D98Q36730432-34DC1EA1-FBEE-46F2-AA68-7CDD9D5EC529Q37214346-436BE018-2B8A-4171-AA83-59DDC042DD04Q37229779-9EB17A8D-132B-4E4D-AA13-A904490320D7Q37360181-F45D7707-3DEA-477F-8C86-E0F1BB9AA9FEQ37616054-756AA013-7DBE-43E8-8C34-51EC06B9B458Q37636665-6253BE06-0915-4F25-9EA7-3B74F04B5C71Q38697698-E8EE4D1D-18E8-4948-B643-E6F9DBC6C2C4Q38869922-8CC148EF-1D2F-4570-BB1E-473E14B5F70BQ42183898-24D7F8F0-6564-4EB3-ADF1-6304D2882799Q42645794-8CCED67C-BD6F-4161-8951-2A5D89B30653Q42669341-D142FC27-A38B-45FC-852A-DA61A3D01C34Q47623927-97F03390-7F92-499E-A173-427AF1621CA4Q47948290-D2BC1840-4974-4969-B23E-019E79240B23Q55347904-595872EF-2BB8-4677-BCAA-1125069DD351Q56761472-55E24035-1E09-4CBA-BAB6-85915C40E816Q58573420-0952DCAB-8CCE-4092-B2AC-86EAF0795967
P2860
Aldehyde dehydrogenase 1A1--a new mediator of resistance to temozolomide in glioblastoma.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Aldehyde dehydrogenase 1A1--a new mediator of resistance to temozolomide in glioblastoma.
@ast
Aldehyde dehydrogenase 1A1--a new mediator of resistance to temozolomide in glioblastoma.
@en
type
label
Aldehyde dehydrogenase 1A1--a new mediator of resistance to temozolomide in glioblastoma.
@ast
Aldehyde dehydrogenase 1A1--a new mediator of resistance to temozolomide in glioblastoma.
@en
prefLabel
Aldehyde dehydrogenase 1A1--a new mediator of resistance to temozolomide in glioblastoma.
@ast
Aldehyde dehydrogenase 1A1--a new mediator of resistance to temozolomide in glioblastoma.
@en
P2093
P2860
P356
P1433
P1476
Aldehyde dehydrogenase 1A1--a new mediator of resistance to temozolomide in glioblastoma.
@en
P2093
Andrea Schäfer
Bernhard Meyer
Christoph P Beier
Florian Ringel
Friederike Schmidt-Graf
Ingrid Hoepner
Jens Gempt
Julia Koeritzer
Julian Teufel
Jürgen Schlegel
P2860
P304
P356
10.1093/NEUONC/NOS270
P577
2012-11-06T00:00:00Z