The broad antibacterial activity of the natural antibody repertoire is due to polyreactive antibodies.
about
Serology in the 21st century: the molecular-level analysis of the serum antibody repertoirePolyreactive Antibodies: Function and QuantificationHow specific is too specific? B-cell responses to viral infections reveal the importance of breadth over depthStructure-Based Reverse Vaccinology Failed in the Case of HIV Because it Disregarded Accepted Immunological TheoryThe effects of diet-induced obesity on B cell functionA novel subpopulation of B-1 cells is enriched with autoreactivity in normal and lupus-prone mice.Linking complement and anti-dsDNA antibodies in the pathogenesis of systemic lupus erythematosusA cryptic polyreactive antibody recognizes distinct clades of HIV-1 glycoprotein 120 by an identical binding mechanism"Rational vaccine design" for HIV should take into account the adaptive potential of polyreactive antibodies.Complement C1 esterase inhibitor levels linked to infections and contaminated heparin-associated adverse eventsPhysical characterization of the "immunosignaturing effect"Fishing for mammalian paradigms in the teleost immune system.Oversulfated chondroitin sulfate inhibits the complement classical pathway by potentiating C1 inhibitor.Older adults have a low capacity to opsonize pneumococci due to low IgM antibody response to pneumococcal vaccinationsNaturally acquired antibodies against Haemophilus influenzae type a in Aboriginal adults, CanadaIn Vitro and In Vivo studies of monoclonal antibodies with prominent bactericidal activity against Burkholderia pseudomallei and Burkholderia mallei.L-rhamnose is often an important part of immunodominant epitope for pneumococcal serotype 23F polysaccharide antibodies in human sera immunized with PPV23.Impact of natural IgM concentration on gene therapy with adenovirus type 5 vectors.Importance of antibodies to lipopolysaccharide in natural and vaccine-induced serum bactericidal activity against Neisseria meningitidis group B.Antibody engineering for increased potency, breadth and half-life.Natural IgM in immune equilibrium and harnessing their therapeutic potential.Evaluation of pneumonia virus of mice as a possible human pathogenDeficient synthesis of class-switched, HIV-neutralizing antibodies to the CD4 binding site and correction by electrophilic gp120 immunogen.Evasion and interactions of the humoral innate immune response in pathogen invasion, autoimmune disease, and cancerAntigen-driven induction of polyreactive IgM during intracellular bacterial infection.Expansion of polyreactive B cells cross-reactive to HLA and self in the blood of a patient with kidney graft rejectionHigh-affinity binding of remyelinating natural autoantibodies to myelin-mimicking lipid bilayers revealed by nanohole surface plasmon resonance.Stimulation of Toll-Like Receptors profoundly influences the titer of polyreactive antibodies in the circulationProperties and function of polyreactive antibodies and polyreactive antigen-binding B cells.Pictorial demonstration of the simultaneous binding of multiple unrelated antigens to individual polyreactive antibody-producing B cellsB-1 cells in the bone marrow are a significant source of natural IgM.Partial reconstitution of humoral immunity and fewer infections in patients with chronic lymphocytic leukemia treated with ibrutinib.Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEXThe link between antibodies to OxLDL and natural protection against pneumococci depends on D(H) gene conservation.Natural and induced B-1 cell immunity to infections raises questions of nature versus nurturePolyreactive antibodies plus complement enhance the phagocytosis of cells made apoptotic by UV-light or HIV.Molecular mechanisms of autoimmunity.Nature and functions of autoantibodies.Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria.Molecular interaction between natural IgG and ficolin--mechanistic insights on adaptive-innate immune crosstalk.
P2860
Q26997997-4B8DE4FD-FFC6-40B4-9F7B-9A7053BA0545Q26999862-723471A8-458D-4BF1-AA22-D225AD8E827FQ27026728-2E3F88EF-A332-4A2F-887A-BCCFE292DB84Q28071559-F7638211-D49C-4263-A499-7FA0EAE10F90Q28383934-30CD2832-1740-4687-B9FC-1D7019935CDAQ30934051-7A08E61E-854A-4761-9D99-9D75367E1673Q33599086-71C719C1-8BC9-4544-823E-3CB5B3981BF7Q33793007-CDE8C064-DDB0-44B8-AA6E-C372F9D99D35Q33941047-893726A7-FDE1-4B4A-BE9A-BB6F4A024CB3Q34238816-8335D4DE-8475-42D1-97D6-03D80C8FDB02Q34248453-C14822B4-68CD-452A-95A2-411FEFE24C48Q34372672-3F4F15E0-4157-40F0-9E9D-7F44EBA28893Q34450711-A907649C-2040-48E8-8CEF-E678A28AE49FQ34484625-37F95978-7977-4A44-8319-F04A38F46DEDQ35037371-B5DE495B-9AAA-42D5-B281-7F932152A78CQ35066127-210A31E0-029E-4F90-92BC-7FC73297117BQ35082637-ADBE6DCF-356E-413D-9451-DE1701BD7BB4Q35111007-21E4F3E0-6547-434F-8BD1-6091E2BFC61FQ35273041-4CF3E497-7C49-42EF-B639-639C6EE28C68Q35575206-9BECDBF8-5286-4476-AE07-DD980B60730DQ35694606-0BE12524-E2C9-46CB-A4A6-C0E57C55DD36Q35943578-80F59B64-887E-4736-8922-0D037D4B7955Q36069818-1ABBCBFC-5EB6-4BEE-8F68-3CE0CB17A384Q36090335-59EF1248-A3ED-4A4E-BE32-B8C3FE0B1CF1Q36106473-3649EAC8-C8BB-4BD3-A837-702CE2E48594Q36110114-BC087B38-FA5C-49CB-A5C5-8DBE8B9D97B4Q36158112-E2DD1F7B-699C-45F5-AC42-43A9C1961734Q36158712-92AB60C5-A354-403C-B49D-9771FEC078A8Q36178686-360C3A7A-B5FE-4C4C-9184-03106D4E713DQ36183175-B321AA3A-EBE9-40F4-8020-5C2776F02EB7Q36185232-F87D4938-F1F7-44DD-A5D7-B4C418BA2BE8Q36253983-3265BAC4-EB73-4B98-BEAD-8E7EC2F8D687Q36300521-4C16CD81-FC35-4BC6-AC23-A10FE75DBB83Q36822711-58523D50-DF27-4B0E-87A0-EC8275874CB2Q36938974-BE29DC88-2EB9-4266-AF06-BB86CA3B461DQ37039612-55DF5285-FFC7-4721-A35A-99FF119B7946Q37103773-9673886C-AD6F-4B59-AC34-395EAF0BB388Q37243935-16A00788-5009-42E3-91DD-11325D3CAB31Q37317730-6774E30D-8C7E-43AC-920D-48D6F5CB18C0Q37475681-92AF269B-5CA1-4EA7-A721-95C70E653D87
P2860
The broad antibacterial activity of the natural antibody repertoire is due to polyreactive antibodies.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
The broad antibacterial activi ...... ue to polyreactive antibodies.
@ast
The broad antibacterial activi ...... ue to polyreactive antibodies.
@en
type
label
The broad antibacterial activi ...... ue to polyreactive antibodies.
@ast
The broad antibacterial activi ...... ue to polyreactive antibodies.
@en
prefLabel
The broad antibacterial activi ...... ue to polyreactive antibodies.
@ast
The broad antibacterial activi ...... ue to polyreactive antibodies.
@en
P2093
P2860
P1433
P1476
The broad antibacterial activi ...... ue to polyreactive antibodies.
@en
P2093
Abner Louis Notkins
John O Cisar
Larry M Wahl
Ya-Fang Hu
Yahong Zhang
Zhao-Hua Zhou
P2860
P356
10.1016/J.CHOM.2007.01.002
P577
2007-03-01T00:00:00Z