Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function. - Wikidata - awgldk - TriplyDB

Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

http://www.wikidata.org/entity/Q36402501

about

TCR-Engineered T Cells Meet New Challenges to Treat Solid Tumors: Choice of Antigen, T Cell Fitness, and Sensitization of Tumor Milieu Interleukin-21 receptor gene induction in human T cells is mediated by T-cell receptor-induced Sp1 activity.Interleukin-15 biology and its therapeutic implications in cancer The biological functions of T helper 17 cell effector cytokines in inflammation IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner Structure and signalling in the IL-17 receptor family Differential effects of IL-21 and IL-15 on perforin expression, lysosomal degranulation, and proliferation in CD8 T cells of patients with human immunodeficiency virus-1 (HIV)Induced Pluripotent Stem Cell as a New Source for Cancer Immunotherapy Improving the clinical impact of biomaterials in cancer immunotherapy.IL-21 Signaling in Immunity Starved and Asphyxiated: How Can CD8(+) T Cells within a Tumor Microenvironment Prevent Tumor Progression Cytokine production and dysregulation in HIV pathogenesis: lessons for development of therapeutics and vaccines Particle-mediated delivery of cytokines for immunotherapy Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes for metastatic melanoma: current status and future outlook Novel immunotherapies for hematologic malignancies The role of interleukin-21 in HIV infection T cell replicative senescence in human aging Identification of the genomic insertion site of Pmel-1 TCR α and β transgenes by next-generation sequencing Crystal Structure of Interleukin-21 Receptor (IL-21R) Bound to IL-21 Reveals That Sugar Chain Interacting with WSXWS Motif Is Integral Part of IL-21R Improving Adoptive T Cell Therapy: The Particular Role of T Cell Costimulation, Cytokines, and Post-Transfer Vaccination Emerging roles of T helper 17 and regulatory T cells in lung cancer progression and metastasis Improving cell-based therapies by nanomodification Synthetic Nanoparticles for Vaccines and Immunotherapy The shared and contrasting roles of IL2 and IL15 in the life and death of normal and neoplastic lymphocytes: implications for cancer therapy Immunology. A chronic need for IL-21 IL-21: roles in immunopathology and cancer therapy Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation Antigen-specific human NKT cells from tuberculosis patients produce IL-21 to help B cells for the production of immunoglobulins In vivo imaging of T cell delivery to tumors after adoptive transfer therapy.A study of T cell tolerance to the tumor-associated antigen MDM2: cytokines can restore antigen responsiveness, but not high avidity T cell function IL-21 limits peripheral lymphocyte numbers through T cell homeostatic mechanisms A phase I study of recombinant human interleukin-21 (rIL-21) in combination with sunitinib in patients with metastatic renal cell carcinoma (RCC).Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer.Interleukin-21 induces the differentiation of human umbilical cord blood CD34-lineage- cells into pseudomature lytic NK cells.T cell receptor (TCR) gene therapy to treat melanoma: lessons from clinical and preclinical studies.Engineered T cells for cancer treatment Targeting a mimotope vaccine to activating Fcgamma receptors empowers dendritic cells to prime specific CD8+ T cell responses in tumor-bearing mice.Re-adapting T cells for cancer therapy: from mouse models to clinical trials.Absence of both IL-7 and IL-15 severely impairs the development of CD8 T cell response against Toxoplasma gondii.

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Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

http://www.wikidata.org/entity/Q36402501

description

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

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Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

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type

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Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

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Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

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prefLabel

Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

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Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

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Journal of Experimental Medicine

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Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function

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P2093

Christian S Hinrichs

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Cynthia A Pise-Masison

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Jay A Berzofsky

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John N Brady

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Michael F Radonovich

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Panu E Kovanen

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Rong Zeng

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Rosanne Spolski

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SangKon Oh

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Steven E Finkelstein

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P2860

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells

Cluster analysis and display of genome-wide expression patterns

Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

Regulation of lymphoid homeostasis by interleukin-15

A critical role for IL-21 in regulating immunoglobulin production

An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes.

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo.

Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

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139-148

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10.1084/JEM.20041057

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1

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201

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Nicholas P. Restifo

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2005-01-01T00:00:00Z

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8101141

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15630141

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2212766

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