Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice - Wikidata - awgldk - TriplyDB

Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice

Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice

http://www.wikidata.org/entity/Q36402881

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Molecular basis of electrophilic and oxidative defense: promises and perils of Nrf2 Role of Nrf2 in oxidative stress and toxicity Endogenous Generation and Signaling Actions of Omega-3 Fatty Acid Electrophilic Derivatives Effect of redox modulating NRF2 activators on chronic kidney disease Impact of air pollution on allergic diseases A perspective on dietary phytochemicals and cancer chemoprevention: oxidative stress, nrf2, and epigenomics Redox control of microglial function: molecular mechanisms and functional significance Roles nrf2 plays in myeloid cells and related disorders Structure of the BTB domain of Keap1 and its interaction with the triterpenoid antagonist CDDO Glutathione redox control of asthma: from molecular mechanisms to therapeutic opportunities Jun dimerization protein 2 is a critical component of the Nrf2/MafK complex regulating the response to ROS homeostasis Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2 Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosis When NRF2 talks, who's listening?Stress-activated cap'n'collar transcription factors in aging and human disease Oridonin confers protection against arsenic-induced toxicity through activation of the Nrf2-mediated defensive response The Nrf2 activator tBHQ inhibits T cell activation of primary human CD4 T cells Redox-dependent anti-inflammatory signaling actions of unsaturated fatty acids Nrf2 plays a pivotal role in protection against burn trauma-induced intestinal injury and death Antiviral activity of Nrf2 in a murine model of respiratory syncytial virus disease Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation Regulation of Nrf2-an update The complexity of the Nrf2 pathway: beyond the antioxidant response The Nrf2 activator, tBHQ, differentially affects early events following stimulation of Jurkat cells Protective effect of nuclear factor E2-related factor 2 on inflammatory cytokine response to brominated diphenyl ether-47 in the HTR-8/SVneo human first trimester extravillous trophoblast cell line Nrf2 regulates chronic lung inflammation and B-cell responses to nontypeable Haemophilus influenzae Antioxidant-induced modification of INrf2 cysteine 151 and PKC-delta-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance Src subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to switch off Nrf2-mediated antioxidant activation of cytoprotective gene expression Oncogene PKCε controls INrf2-Nrf2 interaction in normal and cancer cells through phosphorylation of INrf2 The transcription factor NF-E2-related factor 2 (Nrf2): a protooncogene?Nrf2 signaling and cell survival Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease Inhibitor of Nrf2 (INrf2 or Keap1) protein degrades Bcl-xL via phosphoglycerate mutase 5 and controls cellular apoptosis Th2 skewing by activation of Nrf2 in CD4(+) T cells Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer Dysfunction of Nrf-2 in CF epithelia leads to excess intracellular H2O2 and inflammatory cytokine production Mechanism of chemical activation of Nrf2 Traumatic brain injury induces the activation of the Nrf2-ARE pathway in the lung in rats Dual oxidase regulates neutrophil recruitment in allergic airways Nrf2 is a protective factor against oxidative stresses induced by diesel exhaust particle in allergic asthma

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Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice

http://www.wikidata.org/entity/Q36402881

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Journal of Experimental Medicine

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Disruption of Nrf2 enhances su ...... nflammation and asthma in mice

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Anju Singh

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Jessica Roman

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Jia Guo

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Masayuki Yamamoto

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Rubin M Tuder

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Shyam Biswal

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Steve N Georas

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Thomas W Kensler

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Tirumalai Rangasamy

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Wayne A Mitzner

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P2860

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

Regulatory mechanisms controlling gene expression mediated by the antioxidant response element

Immunologic basis of antigen-induced airway hyperresponsiveness.

Nitric oxide and asthma: a review.

Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury

Roles of mast cells and basophils in innate and acquired immunity.

Tumour necrosis factor-alpha: the role of this multifunctional cytokine in asthma.

New insights into the role of cytokines in asthma

Reactive oxygen species as mediators in asthma.

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47-59

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10.1084/JEM.20050538

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1

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202

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Allison D Fryer

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7745083

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15998787

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