The CENP-L-N Complex Forms a Critical Node in an Integrated Meshwork of Interactions at the Centromere-Kinetochore Interface
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The CENP-T/-W complex is a binding partner of the histone chaperone FACT.The unconventional kinetoplastid kinetochore: from discovery toward functional understandingCentromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition.A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.Integrity of the human centromere DNA repeats is protected by CENP-A, CENP-C, and CENP-T.Stepwise unfolding supports a subunit model for vertebrate kinetochoresCENP-A Is Dispensable for Mitotic Centromere Function after Initial Centromere/Kinetochore Assembly.Bub1 targeting to centromeres is sufficient for Sgo1 recruitment in the absence of kinetochores.Centromere Silencing Mechanisms.A Molecular View of Kinetochore Assembly and Function.Microtubule dynamics decoded by the epigenetic state of centromeric chromatin.Kinetochore assembly and function through the cell cycle.Targeted Protein Degradation by Small Molecules.Structure of centromere chromatin: from nucleosome to chromosomal architecture.Chromatin dynamics during the cell cycle at centromeres.Critical histone post-translational modifications for centromere function and propagation.CENPT bridges adjacent CENPA nucleosomes on young human α-satellite dimers.Astrin-SKAP complex reconstitution reveals its kinetochore interaction with microtubule-bound Ndc80.NuMA recruits dynein activity to microtubule minus-ends at mitosis.The Power of Xenopus Egg Extract for Reconstitution of Centromere and Kinetochore Function.Molecular basis for inner kinetochore configuration through RWD domain-peptide interactions.Decoding the centromeric nucleosome through CENP-N.Critical Foundation of the Kinetochore: The Constitutive Centromere-Associated Network (CCAN).Molecular basis for CENP-N recognition of CENP-A nucleosome on the human kinetochore.Constitutive centromere-associated network contacts confer differential stability on CENP-A nucleosomes in vitro and in the cell.A time out for CENP-A.Human centromere repositioning within euchromatin after partial chromosome deletion.Large-Scale Analysis of CRISPR/Cas9 Cell-Cycle Knockouts Reveals the Diversity of p53-Dependent Responses to Cell-Cycle Defects.CENP-C/H/I/K/M/T/W/N/L and hMis12 but not CENP-S/X participate in complex formation in the nucleoplasm of living human interphase cells outside centromeres.Dynamic regulation of dynein localization revealed by small molecule inhibitors of ubiquitination enzymesReconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80
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P2860
The CENP-L-N Complex Forms a Critical Node in an Integrated Meshwork of Interactions at the Centromere-Kinetochore Interface
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2015 nî lūn-bûn
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name
The CENP-L-N Complex Forms a C ...... ntromere-Kinetochore Interface
@ast
The CENP-L-N Complex Forms a C ...... ntromere-Kinetochore Interface
@en
type
label
The CENP-L-N Complex Forms a C ...... ntromere-Kinetochore Interface
@ast
The CENP-L-N Complex Forms a C ...... ntromere-Kinetochore Interface
@en
prefLabel
The CENP-L-N Complex Forms a C ...... ntromere-Kinetochore Interface
@ast
The CENP-L-N Complex Forms a C ...... ntromere-Kinetochore Interface
@en
P2093
P2860
P1433
P1476
The CENP-L-N Complex Forms a C ...... ntromere-Kinetochore Interface
@en
P2093
Ben E Black
Iain M Cheeseman
Lucie Y Guo
Tonia Tsinman
P2860
P304
P356
10.1016/J.MOLCEL.2015.10.027
P577
2015-11-19T00:00:00Z