Basophils initiate IL-4 production during a memory T-dependent response. - Wikidata - awgldk - TriplyDB

Basophils initiate IL-4 production during a memory T-dependent response.

Basophils initiate IL-4 production during a memory T-dependent response.

http://www.wikidata.org/entity/Q36403845

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Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion Structural similarities of human and mammalian lipocalins, and their function in innate immunity and allergy Cationic amino acid transporter 2 regulates inflammatory homeostasis in the lung A two-step process for cytokine production revealed by IL-4 dual-reporter mice.New paradigms in type 2 immunity.A mechanism for the initiation of allergen-induced T helper type 2 responses IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and Fc gamma RIIb cross-linking.Human cord blood derived immature basophils show dual characteristics, expressing both basophil and eosinophil associated proteins.Basophil-mediated protection against gastrointestinal helminths requires IgE-induced cytokine secretion.Rapid polyclonal desensitization with antibodies to IgE and FcεRIα The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling.A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation.Identification of markers that distinguish IgE- from IgG-mediated anaphylaxis.Systemic impact of intestinal helminth infections.Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system.Basophils are the major producers of IL-4 during primary helminth infection.IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms.Neutrophils clear bacteria associated with parasitic nematodes augmenting the development of an effective Th2-type response.Pathways of murine mast cell development and trafficking: tracking the roots and routes of the mast cell.Cytokine concentrations in bronchoalveolar lavage fluid from horses with neutrophilic inflammatory airway disease.NOD2 and TLR2 ligands trigger the activation of basophils and eosinophils by interacting with dermal fibroblasts in atopic dermatitis-like skin inflammation STAT1 negatively regulates lung basophil IL-4 expression induced by respiratory syncytial virus infection Basophils: what they 'can do' versus what they 'actually do'.IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increasing the number of basophil/mast cell progenitors in the spleen IL-3 is required for increases in blood basophils in nematode infection in mice and can enhance IgE-dependent IL-4 production by basophils in vitro Emerging role of human basophil biology in health and disease.New paradigms in basophil development, regulation and function.Newly appreciated roles for basophils in allergy and protective immunity.Basophil-derived IL-4 plays versatile roles in immunity.Basophils inhibit proliferation of CD4⁺ T cells in autologous and allogeneic mixed lymphocyte reactions and limit disease activity in a murine model of graft versus host disease.The skin is an important bulwark of acquired immunity against intestinal helminths.Direct effects of IL-4 on mast cells drive their intestinal expansion and increase susceptibility to anaphylaxis in a murine model of food allergy.Regulation of the Il4 gene is independently controlled by proximal and distal 3' enhancers in mast cells and basophils.Peanuts can contribute to anaphylactic shock by activating complement.The vascular endothelial specific IL-4 receptor alpha-ABL1 kinase signaling axis regulates the severity of IgE-mediated anaphylactic reactions.The spleen is the site where mast cells are induced in the development of food allergy.Bronchoalveolar lavage fluid cytology and cytokine messenger ribonucleic Acid expression of racehorses with exercise intolerance and lower airway inflammation.Fundamental role of dendritic cells in inducing Th2 responses.

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P2860

Basophils initiate IL-4 production during a memory T-dependent response.

http://www.wikidata.org/entity/Q36403845

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Basophils initiate IL-4 production during a memory T-dependent response.

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Basophils initiate IL-4 production during a memory T-dependent response.

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Basophils initiate IL-4 production during a memory T-dependent response.

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Basophils initiate IL-4 production during a memory T-dependent response.

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Basophils initiate IL-4 production during a memory T-dependent response.

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Basophils initiate IL-4 production during a memory T-dependent response.

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P2093

Crystal Potter

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Fred D Finkelman

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Marat V Khodoun

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Suzanne Morris

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Tatyana Orekhova

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P2860

Active anaphylaxis in IgE-deficient mice

Abolition of anaphylaxis by targeted disruption of the high affinity immunoglobulin E receptor alpha chain gene

Transcription-coupled translation control of AML1/RUNX1 is mediated by cap- and internal ribosome entry site-dependent mechanisms.

Regulation of gene expression by internal ribosome entry sites or cryptic promoters: the eIF4G story

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

Effects of interleukin-3 with or without the c-kit ligand, stem cell factor, on the survival and cytoplasmic granule formation of mouse basophils and mast cells in vitro.

Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors

Regulation of murine B cells through surface immunoglobulin. I. Monoclonal anti-delta antibody that induces allotype-specific proliferation.

Eosinophilia in transgenic mice expressing interleukin 5.

CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3.

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10.1084/JEM.20040598

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7

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200

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