Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha - Wikidata - awgldk - TriplyDB

Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha

Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha

http://www.wikidata.org/entity/Q36403890

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Wnt5a exhibits layer-specific expression in adult skin, is upregulated in psoriasis, and synergizes with type 1 interferon Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity Lifting the silver flakes: the pathogenesis and management of chronic plaque psoriasis Circulating Th17, Th22, and Th1 cells are increased in psoriasis Psoriasis genetics: breaking the barrier Psoriasis pathophysiology: current concepts of pathogenesis Bone Marrow T Cells and the Integrated Functions of Recirculating and Tissue-Resident Memory T Cells Mucosal resident memory CD4 T cells in protection and immunopathology Immunology of psoriasis Resident memory T cells in human health and disease Putting together the psoriasis puzzle: an update on developing targeted therapies Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk Interactions of the Immune System with Skin and Bone Tissue in Psoriatic Arthritis: A Comprehensive Review.Activation of dendritic antigen-presenting cells expressing common heat shock protein receptor CD91 during induction of psoriasis.IL-36 promotes myeloid cell infiltration, activation, and inflammatory activity in skin.Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris Cellular dissection of psoriasis for transcriptome analyses and the post-GWAS era A systems model for immune cell interactions unravels the mechanism of inflammation in human skin.Cytokine-producing dendritic cells in the pathogenesis of inflammatory skin diseases.An epidemiological study on trigger factors and quality of life in psoriatic patients Skin immune sentinels in health and disease.Progress in understanding the immunopathogenesis of psoriasis Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities.Development of a bioengineered skin-humanized mouse model for psoriasis: dissecting epidermal-lymphocyte interacting pathways.Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins.Misbehaving macrophages in the pathogenesis of psoriasis.Psoriasis and its management Assessment of the psoriatic transcriptome in a large sample: additional regulated genes and comparisons with in vitro models.Elucidating new drug targets in psoriasis by gene profiling: an opportunity to be seized.Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells.IL-15 and dermal fibroblasts induce proliferation of natural regulatory T cells isolated from human skin.Mechanisms of human autoimmunity.The psoriatic transcriptome closely resembles that induced by interleukin-1 in cultured keratinocytes: dominance of innate immune responses in psoriasis Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice.Psoriasis: emerging therapeutic strategies.TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice.Lymphocyte trafficking to inflamed skin--molecular mechanisms and implications for therapeutic target molecules.A signature of immune function genes associated with recurrence-free survival in breast cancer patients.Getting under the skin: the immunogenetics of psoriasis.Local immunity by tissue-resident CD8(+) memory T cells.

P2860

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P2860

Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha

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Spontaneous development of pso ...... nd tumor necrosis factor-alpha

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Brian J Nickoloff

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Frank O Nestle

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Hans Peter Hefti

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Mark Suter

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P2860

Functional role of type I and type II interferons in antiviral defense

Interferon gamma contributes to initiation of uterine vascular modification, decidual integrity, and uterine natural killer cell maturation during normal murine pregnancy

Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: a randomised trial

Natural killer cells in antiviral defense: function and regulation by innate cytokines.

Role of the individual interferon systems and specific immunity in mice in controlling systemic dissemination of attenuated pseudorabies virus infection.

Homeostatic T cell proliferation: how far can T cells be activated to self-ligands?

Migration of T cells in vivo: molecular mechanisms and clinical implications.

The immunologic basis for the treatment of psoriasis with new biologic agents.

Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis.

The pathophysiology of tumor necrosis factors.

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