Blocking Wnt signaling by SFRP-like molecules inhibits in vivo cell proliferation and tumor growth in cells carrying active β-catenin.
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γ-Tocotrienol induces paraptosis-like cell death in human colon carcinoma SW620 cellsTargeting leukemia stem cells: which pathways drive self-renewal activity in T-cell acute lymphoblastic leukemia?In vitro study of SPIO-labeled human pancreatic cancer cell line BxPC-3.Genetic methylation and lymphoid malignancies: biomarkers of tumor progression and targeted therapy.Secreted frizzled‑related protein 2 is epigenetically silenced and functions as a tumor suppressor in oral squamous cell carcinoma.Molecular profiling of stroma identifies osteopontin as an independent predictor of poor prognosis in intrahepatic cholangiocarcinoma.Wnt antagonist, secreted frizzled-related protein 1, is involved in prenatal skeletal muscle development and is a target of miRNA-1/206 in pigs.Tocotrienol-rich fraction (TRF) suppresses the growth of human colon cancer xenografts in Balb/C nude mice by the Wnt pathwayInhibition of Wnt/β-catenin signaling by a soluble collagen-derived frizzled domain interacting with Wnt3a and the receptors frizzled 1 and 8.Wnt3a Promotes the Vasculogenic Mimicry Formation of Colon Cancer via Wnt/β-Catenin SignalingHepatocyte-stellate cell cross-talk in the liver engenders a permissive inflammatory microenvironment that drives progression in hepatocellular carcinomaTargeting Wnt pathways in disease.The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapiesWnt2 complements Wnt/β-catenin signaling in colorectal cancer.De novo HAPLN1 expression hallmarks Wnt-induced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas.EZH2 promotes colorectal cancer stem-like cell expansion by activating p21cip1-Wnt/β-catenin signaling.2,3,7,8 Tetrachlorodibenzo-p-dioxin-induced RNA abundance changes identify Ackr3, Col18a1, Cyb5a and Glud1 as candidate mediators of toxicity.Effect of niclosamide on basal-like breast cancers.Wnt signaling and colon carcinogenesis: beyond APC.Sclerostin: a possible target for the management of cancer-induced bone disease.Targeting Wnt signaling in colorectal cancer. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms.Discovery of small molecule inhibitors of the Wnt/β-catenin signaling pathway by targeting β-catenin/Tcf4 interactions.Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer.Pharmacological interventions in the Wnt pathway: inhibition of Wnt secretion versus disrupting the protein-protein interfaces of nuclear factors.A PHD12-Snail2 repressive complex epigenetically mediates neural crest epithelial-to-mesenchymal transition.Dually modified transmembrane proteoglycans in development and disease.The crystal structure of full-length Sizzled from Xenopus laevis yields insights into Wnt-antagonistic function of secreted Frizzled-related proteins.Cell-type specific potent Wnt signaling blockade by bispecific antibody.Rab37 mediates exocytosis of secreted frizzled-related protein 1 to inhibit Wnt signaling and thus suppress lung cancer stemness
P2860
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P2860
Blocking Wnt signaling by SFRP-like molecules inhibits in vivo cell proliferation and tumor growth in cells carrying active β-catenin.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Blocking Wnt signaling by SFRP ...... lls carrying active β-catenin.
@ast
Blocking Wnt signaling by SFRP ...... lls carrying active β-catenin.
@en
type
label
Blocking Wnt signaling by SFRP ...... lls carrying active β-catenin.
@ast
Blocking Wnt signaling by SFRP ...... lls carrying active β-catenin.
@en
prefLabel
Blocking Wnt signaling by SFRP ...... lls carrying active β-catenin.
@ast
Blocking Wnt signaling by SFRP ...... lls carrying active β-catenin.
@en
P2093
P2860
P356
P1433
P1476
Blocking Wnt signaling by SFRP ...... ells carrying active β-catenin
@en
P2093
C Coulouarn
E Lavergne
I Hendaoui
P2860
P2888
P304
P356
10.1038/ONC.2010.432
P407
P577
2010-09-20T00:00:00Z