A novel small-molecule IAP antagonist, AZD5582, draws Mcl-1 down-regulation for induction of apoptosis through targeting of cIAP1 and XIAP in human pancreatic cancer.
about
AZD5582, an IAP antagonist that leads to apoptosis in head and neck squamous cell carcinoma cell lines and is eligible for combination with irradiation.Smac mimetic LCL161 supports neuroblastoma chemotherapy in a drug class-dependent manner and synergistically interacts with ALK inhibitor TAE684 in cells with ALK mutation F1174L.Baculoviral IAP Repeat Containing 6 (BIRC6) Is a Predictor of Prognosis in Prostate Cancer.XIAP 3'-untranslated region serves as a competitor for HMGA2 by arresting endogenous let-7a-5p in human hepatocellular carcinoma.XIAP Limits Autophagic Degradation of Sox2 and Is A Therapeutic Target in Nasopharyngeal Carcinoma Stem Cells.
P2860
A novel small-molecule IAP antagonist, AZD5582, draws Mcl-1 down-regulation for induction of apoptosis through targeting of cIAP1 and XIAP in human pancreatic cancer.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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2015年學術文章
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2015年學術文章
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name
A novel small-molecule IAP ant ...... AP in human pancreatic cancer.
@ast
A novel small-molecule IAP ant ...... AP in human pancreatic cancer.
@en
type
label
A novel small-molecule IAP ant ...... AP in human pancreatic cancer.
@ast
A novel small-molecule IAP ant ...... AP in human pancreatic cancer.
@en
prefLabel
A novel small-molecule IAP ant ...... AP in human pancreatic cancer.
@ast
A novel small-molecule IAP ant ...... AP in human pancreatic cancer.
@en
P2093
P2860
P356
P1433
P1476
A novel small-molecule IAP ant ...... AP in human pancreatic cancer.
@en
P2093
Dae-Won Hong
Daejin Kim
Dong-Hoon Jin
Eun Kyoung Choi
Eun Kyung Choi
Ih-Yeon Hwang
Jae-Sik Shin
Jai-Hee Moon
Jeong Eun Kim
Jeong Hee Kim
P2860
P304
26895-26908
P356
10.18632/ONCOTARGET.4822
P407
P577
2015-08-06T00:00:00Z