about
Emerging therapeutic roles for NAD(+) metabolism in mitochondrial and age-related disordersReprogramming of energy metabolism as a driver of agingPost-Translational Modifications of Cardiac Mitochondrial Proteins in Cardiovascular Disease: Not Lost in TranslationRole of mitochondria in alcoholic liver diseaseSirtuin Functions in Female Fertility: Possible Role in Oxidative Stress and AgingRegulation of mitochondrial pyruvate uptake by alternative pyruvate carrier complexes.The role of sirtuins in cellular homeostasisMitochondrial Metabolism in Aging HeartAcetylation of NDPK-D Regulates Its Subcellular Localization and Cell SurvivalAge-related decrease in the mitochondrial sirtuin deacetylase Sirt3 expression associated with ROS accumulation in the auditory cortex of the mimetic aging rat model.Sirtuin 1 ablation in endothelial cells is associated with impaired angiogenesis and diastolic dysfunction.Prolonged fasting identifies heat shock protein 10 as a Sirtuin 3 substrate: elucidating a new mechanism linking mitochondrial protein acetylation to fatty acid oxidation enzyme folding and function.SIRT5 regulation of ammonia-induced autophagy and mitophagy.Resveratrol Rescues Kidney Mitochondrial Function Following Hemorrhagic Shock.Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects.Reciprocal Changes in Phosphoenolpyruvate Carboxykinase and Pyruvate Kinase with Age Are a Determinant of Aging in Caenorhabditis elegans.SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β.Atrazine exposure causes mitochondrial toxicity in liver and muscle cell lines.Sirt3 prevents maternal obesity-associated oxidative stress and meiotic defects in mouse oocytes.SIRT5 Deficiency Enhances Susceptibility to Kainate-Induced Seizures and Exacerbates Hippocampal Neurodegeneration not through Mitochondrial Antioxidant Enzyme SOD2.Deacetylation by SIRT1 Reprograms Inflammation and CancerObesity and Cardiac Function - The Role of Caloric Excess and its Reversal.Metabolic characterization of a Sirt5 deficient mouse model.Roles of NAD (+) , PARP-1, and Sirtuins in Cell Death, Ischemic Brain Injury, and Synchrotron Radiation X-Ray-Induced Tissue Injury.STAT3 Undergoes Acetylation-dependent Mitochondrial Translocation to Regulate Pyruvate Metabolism.Mitochondrial diaphorases as NAD⁺ donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory inhibition.Regulation of autophagy and mitophagy by nutrient availability and acetylation.Nutrition and health during mid-life: searching for solutions and meeting challenges for the aging population.Matrix revisited: mechanisms linking energy substrate metabolism to the function of the heart.Signaling pathway cross talk in Alzheimer's diseaseMechanisms by which different functional states of mitochondria define yeast longevity.Knock-out of a mitochondrial sirtuin protects neurons from degeneration in Caenorhabditis elegans.Aging and Lung Disease. Clinical Impact and Cellular and Molecular Pathways.Prolonged fasting suppresses mitochondrial NLRP3 inflammasome assembly and activation via SIRT3-mediated activation of superoxide dismutase 2.Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart.Melatonin protects against maternal obesity-associated oxidative stress and meiotic defects in oocytes via the SIRT3-SOD2-dependent pathway.Mechanisms of transcription factor acetylation and consequences in hearts.The role of caloric load and mitochondrial homeostasis in the regulation of the NLRP3 inflammasome.Interplay Between SIRT-3, Metabolism and Its Tumor Suppressor Role in Hepatocellular Carcinoma.SIRT3: Oncogene and Tumor Suppressor in Cancer.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Mitochondrial metabolism, sirtuins, and aging
@ast
Mitochondrial metabolism, sirtuins, and aging
@en
type
label
Mitochondrial metabolism, sirtuins, and aging
@ast
Mitochondrial metabolism, sirtuins, and aging
@en
prefLabel
Mitochondrial metabolism, sirtuins, and aging
@ast
Mitochondrial metabolism, sirtuins, and aging
@en
P2860
P1476
Mitochondrial metabolism, sirtuins, and aging
@en
P2093
Michael N Sack
Toren Finkel
P2860
P356
10.1101/CSHPERSPECT.A013102
P577
2012-12-01T00:00:00Z