Signaling-dependent phosphorylation of mitotic centromere-associated kinesin regulates microtubule depolymerization and its centrosomal localization

Signaling-dependent phosphorylation of mitotic centromere-associated kinesin regulates microtubule depolymerization and its centrosomal localization

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http://www.wikidata.org/entity/Q36418888
The KLP-7 Residue S546 Is a Putative Aurora Kinase Site Required for Microtubule Regulation at the Centrosome in C. elegansSmall molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents.Rac1 and Aurora A regulate MCAK to polarize microtubule growth in migrating endothelial cells.Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation.Spatiotemporal dynamics of Aurora B-PLK1-MCAK signaling axis orchestrates kinetochore bi-orientation and faithful chromosome segregation.Anti-cancer effect of novel PAK1 inhibitor via induction of PUMA-mediated cell death and p21-mediated cell cycle arrest.Structure, biochemistry, and biology of PAK kinases.Molecular insight into the regulation and function of MCAK.Functional analysis of phosphorylation of the mitotic centromere-associated kinesin by Aurora B kinase in human tumor cellsThe activity regulation of the mitotic centromere-associated kinesin by Polo-like kinase 1A Cdk1 phosphomimic mutant of MCAK impairs microtubule end recognition.Deficiency of RITA results in multiple mitotic defects by affecting microtubule dynamics.
P2860

Signaling-dependent phosphorylation of mitotic centromere-associated kinesin regulates microtubule depolymerization and its centrosomal localization

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http://www.wikidata.org/entity/Q36418888
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2012 nî lūn-bûn
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Signaling-dependent phosphoryl ...... d its centrosomal localization
@ast
Signaling-dependent phosphoryl ...... d its centrosomal localization
@en
type
label
Signaling-dependent phosphoryl ...... d its centrosomal localization
@ast
Signaling-dependent phosphoryl ...... d its centrosomal localization
@en
prefLabel
Signaling-dependent phosphoryl ...... d its centrosomal localization
@ast
Signaling-dependent phosphoryl ...... d its centrosomal localization
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932
P356
P1433
P1476
Signaling-dependent phosphoryl ...... d its centrosomal localization
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932