Cross-talk between the Toll-like receptor 4 and Notch1 pathways augments the inflammatory response in the interstitial cells of stenotic human aortic valves.
about
In vitro models of aortic valve calcification: solidifying a systemMolecular and cellular aspects of calcific aortic valve diseaseAugmented osteogenic responses in human aortic valve cells exposed to oxLDL and TLR4 agonist: a mechanistic role of Notch1 and NF-κB interactionIL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells.Soluble biglycan induces the production of ICAM-1 and MCP-1 in human aortic valve interstitial cells through TLR2/4 and the ERK1/2 pathway.Synergy between sphingosine 1-phosphate and lipopolysaccharide signaling promotes an inflammatory, angiogenic and osteogenic response in human aortic valve interstitial cells.Adult aortic valve interstitial cells have greater responses to toll-like receptor 4 stimulation.BMP-2 and TGF-β1 mediate biglycan-induced pro-osteogenic reprogramming in aortic valve interstitial cells.Innate and Adaptive Immunity in Calcific Aortic Valve DiseaseCalcium flux and endothelial dysfunction during acute lung injury: a STIMulating target for therapy.Notch1 promotes the pro-osteogenic response of human aortic valve interstitial cells via modulation of ERK1/2 and nuclear factor-κB activation.Interleukin-1 Beta induces an inflammatory phenotype in human aortic valve interstitial cells through nuclear factor kappa Beta.Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice.Klotho suppresses the inflammatory responses and ameliorates cardiac dysfunction in aging endotoxemic miceEctopic visceral fat: a clinical and molecular perspective on the cardiometabolic risk.Double-stranded RNA upregulates the expression of inflammatory mediators in human aortic valve cells through the TLR3-TRIF-noncanonical NF-κB pathway.Induced pluripotent stem cell modelling of HLHS underlines the contribution of dysfunctional NOTCH signalling to impaired cardiogenesis.Altered MicroRNA Expression Is Responsible for the Pro-Osteogenic Phenotype of Interstitial Cells in Calcified Human Aortic Valves.Ligation of ICAM-1 on human aortic valve interstitial cells induces the osteogenic response: A critical role of the Notch1-NF-κB pathway in BMP-2 expressionValve Interstitial Cells: The Key to Understanding the Pathophysiology of Heart Valve Calcification.A rare case of "subcommissural adhesive aortic stenosis": Triangular struggle of aortic valve area, hemodynamics, and calcium burden.Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis.Crosstalk between TLR4 and Notch1 signaling in the IgA nephropathy during inflammatory response.An epigenetic regulatory loop controls pro-osteogenic activation by TGF-β1 or bone morphogenetic protein 2 in human aortic valve interstitial cells.Klotho suppresses high phosphate-induced osteogenic responses in human aortic valve interstitial cells through inhibition of Sox9.Toll-Like Receptors, Inflammation, and Calcific Aortic Valve Disease.
P2860
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P2860
Cross-talk between the Toll-like receptor 4 and Notch1 pathways augments the inflammatory response in the interstitial cells of stenotic human aortic valves.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Cross-talk between the Toll-li ...... stenotic human aortic valves.
@ast
Cross-talk between the Toll-li ...... stenotic human aortic valves.
@en
type
label
Cross-talk between the Toll-li ...... stenotic human aortic valves.
@ast
Cross-talk between the Toll-li ...... stenotic human aortic valves.
@en
prefLabel
Cross-talk between the Toll-li ...... stenotic human aortic valves.
@ast
Cross-talk between the Toll-li ...... stenotic human aortic valves.
@en
P2093
P2860
P921
P1433
P1476
Cross-talk between the Toll-li ...... f stenotic human aortic valves
@en
P2093
Chunhua Jin
David A Fullerton
Joseph C Cleveland
Xianzhong Meng
P2860
P304
P356
10.1161/CIRCULATIONAHA.111.083675
P407
P433
11 Suppl 1
P577
2012-09-01T00:00:00Z