Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms.
about
The neurokinin 1 receptor antagonist, ezlopitant, reduces appetitive responding for sucrose and ethanolAlcoholism: A Systems Approach From Molecular Physiology to Addictive BehaviorUsing glutamate homeostasis as a target for treating addictive disordersChronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapseTargeting glutamate uptake to treat alcohol use disordersUrocortins: CRF's siblings and their potential role in anxiety, depression and alcohol drinking behavior.P2X4 receptors (P2X4Rs) represent a novel target for the development of drugs to prevent and/or treat alcohol use disordersProteomic approaches and identification of novel therapeutic targets for alcoholismRecent advances in the discovery and preclinical testing of novel compounds for the prevention and/or treatment of alcohol use disorders.Rational development of addiction pharmacotherapies: successes, failures, and prospectsMedications for unhealthy alcohol use: across the spectrum.A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction.Metabotropic Glutamate Receptor 7 (mGluR7) as a Target for the Treatment of Psychostimulant DependenceHominids adapted to metabolize ethanol long before human-directed fermentationNeurokinin 1 receptor antagonism as a possible therapy for alcoholismInhibition of phosphodiesterase 4 reduces ethanol intake and preference in C57BL/6J miceThe dual orexin/hypocretin receptor antagonist, almorexant, in the ventral tegmental area attenuates ethanol self-administrationVariation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stressEffects of Acamprosate on Neuronal Receptors and Ion Channels Expressed inXenopusOocytesThe efficacy of a low dose combination of topiramate and naltrexone on ethanol reinforcement and consumption in rat models.Update on neuropharmacological treatments for alcoholism: scientific basis and clinical findings.Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validityDesign, synthesis, and biological evaluation of aminoalkylindole derivatives as cannabinoid receptor ligands with potential for treatment of alcohol abuse.Nalmefene for the treatment of alcohol use disorders: recent data and clinical potential.World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Substance Use and Related Disorders, Part 1: Alcoholism.Targets for ethanol action and antagonism in loop 2 of the extracellular domain of glycine receptors.Genome-wide gene expression analysis identifies K-ras as a regulator of alcohol intakeFurther characterization of the GlyT-1 inhibitor Org25935: anti-alcohol, neurobehavioral, and gene expression effects.Genetic influences on response to alcohol and response to pharmacotherapies for alcoholism.Neurobiological mechanisms contributing to alcohol-stress-anxiety interactions.Genetics and genomics of alcohol sensitivityThe clinical significance of drug cravingInteroceptive effects of alcohol require mGlu5 receptor activity in the nucleus accumbensOperant sensation seeking requires metabotropic glutamate receptor 5 (mGluR5).Metabotropic glutamate receptor 5 activity in the nucleus accumbens is required for the maintenance of ethanol self-administration in a rat genetic model of high alcohol intakeEffects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependenceAcamprosate and naltrexone treatment effects on ethanol and sucrose seeking and intake in ethanol-dependent and nondependent ratsTreatment of alcohol dependence with low-dose topiramate: an open-label controlled study.Brucine suppresses ethanol intake and preference in alcohol-preferring Fawn-Hooded rats.Long-lasting reduction in hippocampal neurogenesis by alcohol consumption in adolescent nonhuman primates.
P2860
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P2860
Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms.
@ast
Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms.
@en
type
label
Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms.
@ast
Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms.
@en
prefLabel
Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms.
@ast
Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms.
@en
P1476
Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms.
@en
P2093
Markus Heilig
P304
P356
10.1016/J.PHARMTHERA.2006.02.001
P577
2006-03-20T00:00:00Z