about
Phyla- and Subtype-Selectivity of CgNa, a Na Channel Toxin from the Venom of the Giant Caribbean Sea Anemone Condylactis GiganteaThe NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic beta-cell lineChannelopathiesIon channel gene expression in the inner earDrugs acting on SUR1 to treat CNS ischemia and traumaThe sodium leak channel, NALCN, in health and diseaseCell biology and pathology of podocytesReal-time visualization of conformational changes within single MloK1 cyclic nucleotide-modulated channels.Asteropsin A: An unusual cystine-crosslinked peptide from porifera enhances neuronal Ca2+ influxPermanent neonatal diabetes caused by dominant, recessive, or compound heterozygous SUR1 mutations with opposite functional effects.Gain-of-function mutations in potassium channel subunit KCNE2 associated with early-onset lone atrial fibrillationIon-channel modulators: more diversity than previously thoughtKv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillationLocating the route of entry and binding sites of benzocaine and phenytoin in a bacterial voltage gated sodium channelProperties of protein drug target classesSLEEPLESS is a bifunctional regulator of excitability and cholinergic synaptic transmissionPotassium channels in articular chondrocytesInhibition of NaV1.6 sodium channel currents by a novel series of 1,4-disubstituted-triazole derivatives obtained via copper-catalyzed click chemistry.Two conserved arginine residues from the SK3 potassium channel outer vestibule control selectivity of recognition by scorpion toxins.Sudden cardiac death prediction and prevention: report from a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop.Ion channels and schizophrenia: a gene set-based analytic approach to GWAS data for biological hypothesis testing.KCNQ channels show conserved ethanol block and function in ethanol behaviour.Engineering biosynthetic excitable tissues from unexcitable cells for electrophysiological and cell therapy studies.Searching for interesting channels: pairing selection and molecular evolution methods to study ion channel structure and function.Co-localization of putative calcium channels (phenylalkylamine-binding sites) on oil bodies in protoplasts from dark-grown sunflower seedling cotyledonsIon conduction in ligand-gated ion channels: Brownian dynamics studies of four recent crystal structures.Annotation of functional impact of voltage-gated sodium channel mutations.Quaternary structure of KATP channel SUR2A nucleotide binding domains resolved by synchrotron radiation X-ray scattering.Constitutive endocytic recycling and protein kinase C-mediated lysosomal degradation control K(ATP) channel surface densityDomain-based identification and analysis of glutamate receptor ion channels and their relatives in prokaryotes.Progress in the structural understanding of voltage-gated calcium channel (CaV) function and modulation.Big Potassium (BK) ion channels in biology, disease and possible targets for cancer immunotherapy.Open conformation of hERG channel turrets revealed by a specific scorpion toxin BmKKx2Testing the applicability of Nernst-Planck theory in ion channels: comparisons with Brownian dynamics simulations.Sequencing studies in human genetics: design and interpretation.Drosophila KCNQ channel displays evolutionarily conserved electrophysiology and pharmacology with mammalian KCNQ channels.Role of potassium ion channels in detrusor smooth muscle function and dysfunctionDifferential sensitivities of the vascular K(ATP) channel to various PPAR activatorsIsoform-specific prolongation of Kv7 (KCNQ) potassium channel opening mediated by new molecular determinants for drug-channel interactionsVoltage-gated Na+ channel SCN5A is a key regulator of a gene transcriptional network that controls colon cancer invasion
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
From molecule to malady.
@ast
From molecule to malady.
@en
type
label
From molecule to malady.
@ast
From molecule to malady.
@en
prefLabel
From molecule to malady.
@ast
From molecule to malady.
@en
P2860
P356
P1433
P1476
From molecule to malady.
@en
P2093
Frances M Ashcroft
P2860
P2888
P304
P356
10.1038/NATURE04707
P407
P577
2006-03-01T00:00:00Z
P6179
1049499017