Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth. - Wikidata - awgldk - TriplyDB

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.

http://www.wikidata.org/entity/Q36429062

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Clinical significance of T cell metabolic reprogramming in cancer Targeting NK Cells for Anticancer Immunotherapy: Clinical and Preclinical Approaches Combination Approaches with Immune-Checkpoint Blockade in Cancer Therapy PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations Elevated Cellular PD1/PD-L1 Expression Confers Acquired Resistance to Cisplatin in Small Cell Lung Cancer Cells PD-L1, PD-L2 and PD-1 expression in metastatic melanoma: Correlation with tumor-infiltrating immune cells and clinical outcome.CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells.Comparative transcriptomic and proteomic analyses provide insights into the key genes involved in high-altitude adaptation in the Tibetan pig HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT).The PD-1/PD-L1 inhibitory pathway is altered in pre-eclampsia and regulates T cell responses in pre-eclamptic rats.Enhanced Tumor Control with Combination mTOR and PD-L1 Inhibition in Syngeneic Oral Cavity Cancers Molecular Imaging of Immunotherapy Targets in Cancer.Co-expression of PD-L1 and p-AKT is associated with poor prognosis in diffuse large B-cell lymphoma via PD-1/PD-L1 axis activating intracellular AKT/mTOR pathway in tumor cells A New VISTA on combination therapy for negative checkpoint regulator blockade.An unexpected N-terminal loop in PD-1 dominates binding by nivolumab.Rational combination of oncolytic vaccinia virus and PD-L1 blockade works synergistically to enhance therapeutic efficacy.Microenvironment inflammatory infiltrate drives growth speed and outcome of hepatocellular carcinoma: a prospective clinical study.PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity.Immunotherapy for advanced melanoma: future directions.PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity.Anti-PD-L1 treatment enhances antitumor effect of everolimus in a mouse model of renal cell carcinoma.Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma.Cytokines and metabolic factors regulate tumoricidal T-cell function during cancer immunotherapy.Promoter methylation of the immune checkpoint receptor PD-1 (PDCD1) is an independent prognostic biomarker for biochemical recurrence-free survival in prostate cancer patients following radical prostatectomy T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy.Efficacy of Juzentaihoto for Tumor Immunotherapy in B16 Melanoma Metastasis Model.PD-L1 predicts poor prognosis for nasopharyngeal carcinoma irrespective of PD-1 and EBV-DNA load.mTORC1 and mTORC2 in cancer and the tumor microenvironment.Crystal clear: visualizing the intervention mechanism of the PD-1/PD-L1 interaction by two cancer therapeutic monoclonal antibodies.Interplay between Immune Checkpoint Proteins and Cellular Metabolism.Obstacles Posed by the Tumor Microenvironment to T cell Activity: A Case for Synergistic Therapies.The Role of Dendritic Cell Maturation in the Induction of Insulin-Dependent Diabetes Mellitus.Immunometabolic Regulations Mediated by Coinhibitory Receptors and Their Impact on T Cell Immune Responses.Are Mast Cells MASTers in Cancer?Metabolic Instruction of Immunity.Skin Cancers in Organ Transplant Recipients.Metabolic reprogramming in the tumour microenvironment: a hallmark shared by cancer cells and T lymphocytes.PD1 signal transduction pathways in T cells.PD-1 Checkpoint Blockade in Combination with an mTOR Inhibitor Restrains Hepatocellular Carcinoma Growth Induced by Hepatoma Cell-Intrinsic PD-1.In situ and in silico kinetic analyses of programmed cell death-1 (PD-1) receptor, programmed cell death ligands, and B7-1 protein interaction network.

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Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.

http://www.wikidata.org/entity/Q36429062

description

2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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2015年學術文章

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2015年學術文章

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name

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.

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Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.

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Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.

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Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.

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prefLabel

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.

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Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.

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J.CELL.2015.08.052

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Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.

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Antonio Cozzio

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Arlene H Sharpe

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Christine G Lian

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Christoph Schlapbach

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Christopher P Elco

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George F Murphy

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Hansgeorg Mueller

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Keith T Flaherty

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Martin C Mihm

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Nayoung Lee

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P2860

Modulation of T-cell activation by malignant melanoma initiating cells

Identification of cells initiating human melanomas

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

Immune Checkpoint Blockade in Cancer Therapy

Combined targeting of MEK and PI3K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivo.

Nivolumab plus ipilimumab in advanced melanoma.

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

The blockade of immune checkpoints in cancer immunotherapy

Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth

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1242-1256

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10.1016/J.CELL.2015.08.052

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6

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162

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Emmanuella Guenova

Markus H. Frank

Christian Posch

Tobias Schatton

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2015-09-01T00:00:00Z

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26359984

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4700833

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