The tRNA methyltransferase NSun2 stabilizes p16INK⁴ mRNA by methylating the 3'-untranslated region of p16
about
NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAsmRNA methylation by NSUN2 in cell proliferationModify or die?--RNA modification defects in metazoansIdentification of NAD+ capped mRNAs in Saccharomyces cerevisiaeCurrent aging research in China.Overexpression of NSUN2 by DNA hypomethylation is associated with metastatic progression in human breast cancer.Characterizing 5-methylcytosine in the mammalian epitranscriptome.Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex.Chemical and structural effects of base modifications in messenger RNA.Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6The molecular balancing act of p16(INK4a) in cancer and aging.tRNA modifying enzymes, NSUN2 and METTL1, determine sensitivity to 5-fluorouracil in HeLa cellsMethylation by NSun2 represses the levels and function of microRNA 125b.Role of RNA methyltransferases in tissue renewal and pathologyNovel RNA modifications in the nervous system: form and functionFrom cis-regulatory elements to complex RNPs and back.NSun2 Promotes Cell Growth via Elevating Cyclin-Dependent Kinase 1 Translation.Proteinase-activated receptor 2 promotes cancer cell migration through RNA methylation-mediated repression of miR-125b.NSun2 delays replicative senescence by repressing p27 (KIP1) translation and elevating CDK1 translation.Deposition of 5-Methylcytosine on Enhancer RNAs Enables the Coactivator Function of PGC-1α.RNA methyltransferase NSUN2 promotes stress-induced HUVEC senescence.Stem cell function and stress response are controlled by protein synthesis.let-7-repressesed Shc translation delays replicative senescence.Mapping and significance of the mRNA methylome.HuR and post-transcriptional regulation in vascular aging.miRNA and methylation: a multifaceted liaison.Association of tRNA methyltransferase NSUN2/IGF-II molecular signature with ovarian cancer survival.Epigenetic modification of nucleic acids: from basic studies to medical applications.A Novel Single-Nucleotide Deletion (c.1020delA) in NSUN2 Causes Intellectual Disability in an Emirati Child.NSUN2-Mediated m5C Methylation and METTL3/METTL14-Mediated m6A Methylation Cooperatively Enhance p21 Translation.Sequence-specific and Shape-selective RNA Recognition by the Human RNA 5-Methylcytosine Methyltransferase NSun6.RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells.
P2860
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P2860
The tRNA methyltransferase NSun2 stabilizes p16INK⁴ mRNA by methylating the 3'-untranslated region of p16
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
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name
The tRNA methyltransferase NSu ...... 3'-untranslated region of p16
@ast
The tRNA methyltransferase NSu ...... 3'-untranslated region of p16
@en
type
label
The tRNA methyltransferase NSu ...... 3'-untranslated region of p16
@ast
The tRNA methyltransferase NSu ...... 3'-untranslated region of p16
@en
prefLabel
The tRNA methyltransferase NSu ...... 3'-untranslated region of p16
@ast
The tRNA methyltransferase NSu ...... 3'-untranslated region of p16
@en
P2093
P2860
P921
P356
P1476
The tRNA methyltransferase NSu ...... 3'-untranslated region of p16
@en
P2093
Junyue Xing
Minqwei Yu
Tanjun Tong
Wengong Wang
Xiaotian Zhang
Yongfeng Shang
Zhenyun Liu
P2860
P2888
P356
10.1038/NCOMMS1692
P407
P577
2012-03-06T00:00:00Z