Enhancement by O6-benzyl-N2-acetylguanosine of N'-[2-chloroethyl]-N-[2-(methylsulphonyl)ethyl]-N'-nitrosourea therapeutic index on nude mice bearing resistant human melanoma - Wikidata - awgldk - TriplyDB

Enhancement by O6-benzyl-N2-acetylguanosine of N'-[2-chloroethyl]-N-[2-(methylsulphonyl)ethyl]-N'-nitrosourea therapeutic index on nude mice bearing resistant human melanoma

Enhancement by O6-benzyl-N2-acetylguanosine of N'-[2-chloroethyl]-N-[2-(methylsulphonyl)ethyl]-N'-nitrosourea therapeutic index on nude mice bearing resistant human melanoma

http://www.wikidata.org/entity/Q36431304

about

Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and caspase-3 activation in M4Beu melanoma cells.Higher skeletal muscle protein synthesis and lower breakdown after chemotherapy in cachectic mice.

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P2860

Enhancement by O6-benzyl-N2-acetylguanosine of N'-[2-chloroethyl]-N-[2-(methylsulphonyl)ethyl]-N'-nitrosourea therapeutic index on nude mice bearing resistant human melanoma

http://www.wikidata.org/entity/Q36431304

description

1997 nî lūn-bûn

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1997年の論文

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年學術文章

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1997年學術文章

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1997年學術文章

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name

Enhancement by O6-benzyl-N2-ac ...... aring resistant human melanoma

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Enhancement by O6-benzyl-N2-ac ...... aring resistant human melanoma

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Enhancement by O6-benzyl-N2-ac ...... aring resistant human melanoma

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Enhancement by O6-benzyl-N2-ac ...... aring resistant human melanoma

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Enhancement by O6-benzyl-N2-ac ...... aring resistant human melanoma

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British Journal of Cancer

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Enhancement by O6-benzyl-N2-ac ...... aring resistant human melanoma

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Cussac-Buchdhal C

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Debiton E

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Dupuy JM

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Madelmont JC

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Maurizis JC

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Mounetou E

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Rapp M

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Veyre A

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P2860

Repair of DNA containing O6-alkylguanine

Regulation and expression of the adaptive response to alkylating agents

Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents.

Metabolism of the chloroethylnitrosoureas.

Importance of the DNA repair enzyme O6-alkyl guanine alkyltransferase (AT) in cancer chemotherapy.

Melanoma: chemotherapy.

O6-alkylguanine-DNA alkyltransferase. A target for the modulation of drug resistance.

Structure, function, and inhibition of O6-alkylguanine-DNA alkyltransferase.

Depletion of O6-alkylguanine-DNA alkyltransferase correlates with potentiation of temozolomide and CCNU toxicity in human tumour cells.

Synergistic efficacy of O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in a human colon cancer xenograft completely resistant to BCNU alone.

P2888

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1157-1162

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10.1038/BJC.1997.527

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9

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1021086584

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9365163

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2228110

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