Gαs promotes EEA1 endosome maturation and shuts down proliferative signaling through interaction with GIV (Girdin). - Wikidata - awgldk - TriplyDB

Gαs promotes EEA1 endosome maturation and shuts down proliferative signaling through interaction with GIV (Girdin).

Gαs promotes EEA1 endosome maturation and shuts down proliferative signaling through interaction with GIV (Girdin).

http://www.wikidata.org/entity/Q36433811

about

Activators of G protein signaling exhibit broad functionality and define a distinct core signaling triad Visualization of self-delivering hydrophobically modified siRNA cellular internalization.Genome-wide mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin.Endocytosis, signaling, and beyond Transcriptional profiling and dynamical regulation analysis identify potential kernel target genes of SCYL1-BP1 in HEK293T cells.Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin.Sm16, a major component of Schistosoma mansoni cercarial excretory/secretory products, prevents macrophage classical activation and delays antigen processing.Expression of Girdin in primary hepatocellular carcinoma and its effect on cell proliferation and invasion.Multimodular biosensors reveal a novel platform for activation of G proteins by growth factor receptors.GIV/Girdin transmits signals from multiple receptors by triggering trimeric G protein activation.IQGAP1 promotes CXCR4 chemokine receptor function and trafficking via EEA-1+ endosomes Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration-proliferation dichotomy Activation of G proteins by GIV-GEF is a pivot point for insulin resistance and sensitivity.CCDC88A mutations cause PEHO-like syndrome in humans and mouse Gαs regulates the post-endocytic sorting of G protein-coupled receptors ARH directs megalin to the endocytic recycling compartment to regulate its proteolysis and gene expression.GIV/Girdin activates Gαi and inhibits Gαs via the same motif Gαs protein expression is an independent predictor of recurrence in prostate cancer Heterotrimeric G protein signaling via GIV/Girdin: Breaking the rules of engagement, space, and time.G protein coupled growth factor receptor tyrosine kinase: no longer an oxymoron.Marilyn Farquhar: from the beginning. Interview by Sedwick Caitlin.Biochemical, Biophysical and Cellular Techniques to Study the Guanine Nucleotide Exchange Factor, GIV/Girdin.S1PR3 Signaling Drives Bacterial Killing and Is Required for Survival in Bacterial Sepsis.Membrane Recruitment of the Non-receptor Protein GIV/Girdin (Gα-interacting, Vesicle-associated Protein/Girdin) Is Sufficient for Activating Heterotrimeric G Protein Signaling.Proteomics reveals novel protein associations with early endosomes in an epidermal growth factor-dependent manner.

P2860

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P2860

Gαs promotes EEA1 endosome maturation and shuts down proliferative signaling through interaction with GIV (Girdin).

http://www.wikidata.org/entity/Q36433811

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

Gαs promotes EEA1 endosome mat ...... interaction with GIV (Girdin).

@ast

Gαs promotes EEA1 endosome mat ...... interaction with GIV (Girdin).

@en

type

label

Gαs promotes EEA1 endosome mat ...... interaction with GIV (Girdin).

@ast

Gαs promotes EEA1 endosome mat ...... interaction with GIV (Girdin).

@en

prefLabel

Gαs promotes EEA1 endosome mat ...... interaction with GIV (Girdin).

@ast

Gαs promotes EEA1 endosome mat ...... interaction with GIV (Girdin).

@en

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P356

MBC.E12-02-0133

P1433

Molecular Biology of the Cell

P1476

Gαs promotes EEA1 endosome mat ...... interaction with GIV (Girdin).

@en

P2093

Anthony O Beas

http://www.w3.org/2001/XMLSchema#string

Carmen Teodorof

http://www.w3.org/2001/XMLSchema#string

Lien T Nguyen

http://www.w3.org/2001/XMLSchema#string

Vanessa Taupin

http://www.w3.org/2001/XMLSchema#string

P2860

Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles

Identification of the switch in early-to-late endosome transition

Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

MVB vesicle formation: ESCRT-dependent, ESCRT-independent and everything in between

Endosome maturation

Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome.

Rab conversion as a mechanism of progression from early to late endosomes

Endocytosis and signalling: intertwining molecular networks

P304

4623-4634

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scholarly article

P356

10.1091/MBC.E12-02-0133

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23

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P478

23

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Mikel Garcia-Marcos

Marilyn Farquhar

P577

2012-10-10T00:00:00Z

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23051738

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3510023

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