Hippo signaling regulates pancreas development through inactivation of Yap. - Wikidata - awgldk - TriplyDB

Hippo signaling regulates pancreas development through inactivation of Yap.

Hippo signaling regulates pancreas development through inactivation of Yap.

http://www.wikidata.org/entity/Q36435165

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Mst1 and Mst2 kinases: regulations and diseases The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment Functional role of Mst1/Mst2 in embryonic stem cell differentiation Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer The Hippo pathway effector YAP is an essential regulator of ductal progenitor patterning in the mouse submandibular gland.The Hippo pathway in disease and therapy: cancer and beyond Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma Spatiotemporal proteomic analyses during pancreas cancer progression identifies serine/threonine stress kinase 4 (STK4) as a novel candidate biomarker for early stage disease.Regeneration and repair of the exocrine pancreas.Disease implications of the Hippo/YAP pathway.Hippo signaling pathway in liver and pancreas: the potential drug target for tumor therapy.TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors.Low RASSF6 expression in pancreatic ductal adenocarcinoma is associated with poor survival.Tshz1 Regulates Pancreatic β-Cell Maturation.Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass.Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling Snail1 is required for the maintenance of the pancreatic acinar phenotype.Hippo signaling regulates differentiation and maintenance in the exocrine pancreas Identification of genetic interaction networks via an evolutionary algorithm evolved Bayesian network.Dual function of Yap in the regulation of lens progenitor cells and cellular polarity.Hippo Pathway and Skeletal Muscle Mass Regulation in Mammals: A Controversial Relationship.The mammalian Hippo pathway: regulation and function of YAP1 and TAZ.Yap1 plays a protective role in suppressing free fatty acid-induced apoptosis and promoting beta-cell survival.Intrinsic and extrinsic regulatory mechanisms are required to form and maintain a lens of the correct size and shape.YAP/TAZ at the Roots of Cancer.Hippo vs. Crab: tissue-specific functions of the mammalian Hippo pathway.Proproliferative and antiapoptotic action of exogenously introduced YAP in pancreatic β cells.YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling.Gatekeepers of pancreas: TEAD and YAP.Integrin-FAK-CDC42-PP1A signaling gnaws at YAP/TAZ activity to control incisor stem cells.Cellular and molecular mechanisms coordinating pancreas development.Expression profile and prognostic value of SAV1 in patients with pancreatic ductal adenocarcinoma.Pancreatic Exocrine Tissue Architecture and Integrity are Maintained by E-cadherin During Postnatal Development

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P2860

Hippo signaling regulates pancreas development through inactivation of Yap.

http://www.wikidata.org/entity/Q36435165

description

2012 nî lūn-bûn

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2012年の論文

@ja

2012年学术文章

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2012年学术文章

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2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

Hippo signaling regulates pancreas development through inactivation of Yap.

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Hippo signaling regulates pancreas development through inactivation of Yap.

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type

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Hippo signaling regulates pancreas development through inactivation of Yap.

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Hippo signaling regulates pancreas development through inactivation of Yap.

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prefLabel

Hippo signaling regulates pancreas development through inactivation of Yap.

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Hippo signaling regulates pancreas development through inactivation of Yap.

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P1433

Molecular and Cellular Biology

P1476

Hippo signaling regulates pancreas development through inactivation of Yap.

@en

P2093

Brian P Boerner

http://www.w3.org/2001/XMLSchema#string

Caroline E Day

http://www.w3.org/2001/XMLSchema#string

Nicholas M George

http://www.w3.org/2001/XMLSchema#string

Nora E Sarvetnick

http://www.w3.org/2001/XMLSchema#string

Randy L Johnson

http://www.w3.org/2001/XMLSchema#string

P2860

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

Yap1 acts downstream of α-catenin to control epidermal proliferation

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

TEAD mediates YAP-dependent gene induction and growth control

The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

The hippo signaling pathway in development and cancer

TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm

mTOR signaling in growth control and disease

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity

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5116-5128

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scholarly article

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10.1128/MCB.01034-12

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24

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32

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2012-10-15T00:00:00Z

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232256732

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23071096

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Aizkuņģa dziedzeris

P932

3510525

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